Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The data are presented concerning the induction of bovine leukemia with purified and concentrated C-type oncornaviruses isolated from cattle of Latvian Brown breed with persistent lympholeukemia. The calves induced with C-type oncornaviruses were found to have early signs of persistent lympholeukemia. Pathohistological changes suggesting persistent lympholeukemia were observed to precede early clinical and hematological signs of the disease. C-type oncornaviruses were reisolated from blood plasma of calves with experimentally induced lympholeukemia.
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PMID:Induction of bovine leukemia C-type oncornaviruses. 82 25

Calves of two breeds--Brown Latvian and Black and White, were immunized against bovine leukemia virus with an immunogen produced from short-term cultured blood lymphocytes of BLV-positive Brown Latvian cows. The immunogen contained the viral proteins gp51 and p24 as well as some cellular proteins. As determined by bioassay in sheep, it did not contain infective bovine leukemia virus. The calves were challenged by BLV-producing lymphocytes 2 weeks after the immunization procedure. Effective protection against BLV infection was induced by the tested immunogen in all Brown Latvian calves for 6 months and in 70% of the Black and White calves.
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PMID:Protection against bovine leukemia virus infection in two breeds of cattle. 838 92