Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Studies were conducted to compare the antibody production of the Delayed Amelanotic (DAM) line of chickens with that of the line from which it originated, the Brown line (BR), and a distantly related environmental control, the Light Brown Leghorn (LBL). Total agglutinating antibody titers following immunization with sheep red blood cells (SRBC) or Brucella abortus (BA), were determined at 4, 6, 8, 10, 12, 16, and 20 weeks. The SRBC titers of DAM line birds were significantly higher than those of LBL birds but not BR birds at young ages (4 to 8 weeks) and at 20 weeks. The BA titers of DAM and BR lines were significantly higher than those of the LBL line at 4 and 6 weeks. We conclude that the DAM line exhibits hyperreactivity in B-cell function, which may be related to the line-associated pigmentation destruction. These studies also confirm that age is an important factor in making comparisons of antibody production between different genetic stocks.
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PMID:Effect of selection for delayed amelanosis on immune response in chickens. 1. Antibody production. 642 16

Brown-headed gulls (Larus brunnicephalus), winter visitors of Thailand, were tracked by satellite telemetry during 2008-2011 for investigating their roles in the highly pathogenic avian influenza (HPAI) H5N1 virus spread. Eight gulls negative for influenza virus infection were marked with solar-powered satellite platform transmitters at Bang Poo study site in Samut Prakarn province, Thailand; their movements were monitored by the Argos satellite tracking system, and locations were mapped. Five gulls completed their migratory cycles, which spanned 7 countries (China, Bangladesh, India, Myanmar, Thailand, Cambodia, and Vietnam) affected by the HPAI H5N1 virus. Gulls migrated from their breeding grounds in China to stay overwinter in Thailand and Cambodia; while Bangladesh, India, Myanmar, and Vietnam were the places of stopovers during migration. Gulls traveled an average distance of about 2400 km between Thailand and China and spent 1-2 weeks on migration. Although AI surveillance among gulls was conducted at the study site, no AI virus was isolated and no H5N1 viral genome or specific antibody was detected in the 75 gulls tested, but 6.6% of blood samples were positive for pan-influenza A antibody. No AI outbreaks were reported in areas along flyways of gulls in Thailand during the study period. Distance and duration of migration, tolerability of the captive gulls to survive the HPAI H5N1 virus challenge and days at viral shedding after the virus challenging suggested that the Brown-headed gull could be a potential species for AI spread, especially among Southeast Asian countries, the epicenter of H5N1 AI outbreak.
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PMID:Satellite tracking on the flyways of brown-headed gulls and their potential role in the spread of highly pathogenic avian influenza H5N1 virus. 2320 23