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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a recent large series of tendon sheath syndrome, Brown reported only five cases of the pure acquired type that were not intermittent and in which the patients did not undergo spontaneous recovery. The origin of acquired Brown's syndrome is varied and includes trauma of the orbit, direct trochlear trauma, orbital or muscle surgery, frontal sinusitis or sinus surgery, and inflammation of the superior oblique tendon and sheath, namely a stenosing tenosynovitis. The differential diagnosis and possible causes of the acquired Brown's syndrome were reviewed, and two cases of presumptive tenosynovitis of the superior oblique tendon and sheath are presented in detail. In both cases, the condition of each patient was notably improved by a series of direct injections of methylprednisolone acetate into the trochlear region. This form of treatment for acquired Brown's syndrome of inflammatory origin has never, to my knowledge, been reported in the literature.
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PMID:Acquired Brown's syndrome of inflammatory origin. Response to locally injected steroids. 66 32

Tenosynovitis in rheumatic disorders may affect ocular muscles producing symptoms unfamiliar to rheumatologists. We present a case of superior oblique tenosynovitis (Brown's syndrome) as an early rheumatic manifestation in a patient with systemic lupus erythematosus.
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PMID:Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation. 226 41

A 27 year old woman with systemic lupus erythematosus (SLE) developed vertical diplopia with an apparent bilateral inferior oblique muscle palsy, resulting in a limitation of elevation of the globe in adduction. It resolved with systemic steroid treatment. A transient tenosynovitis affecting the superior oblique tendons was the probable underlying pathological mechanism. This is the first described case of Brown's syndrome associated with SLE.
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PMID:Acquired Brown's syndrome in a patient with systemic lupus erythematosus. 832 90

A 25 year-old woman, known to be suffering from destructive rheumatoid arthritis, was admitted to the hospital due to influenza-like symptoms lasting three weeks. Adult Still's disease was diagnosed. During her disease she developed painful ophthalmoplegia due to tenosynovitis of the superior oblique muscle and tendon sheath (Brown's syndrome). Total resolution was obtained within three weeks of corticosteroid therapy.
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PMID:[Brown syndrome in an adult patient with morbus Still]. 962 84

Acquired Brown's syndrome is a disorder of ocular mobility characterized by the inability to elevate the affected eye in full adduction owing to inflammatory tenosynovitis of the superior oblique tendon. We describe a child who developed Brown's syndrome as a complication of poststreptococcal reactive arthritis.
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PMID:Acquired Brown's syndrome in a child with poststreptococcal reactive arthritis. 1176 28

The isolation of reoviruses from broiler breeder and layer replacement stock affected with tenosynovitis is recorded. Experimental inoculation of the reovirus isolates in Brown Leghorn chickens produced mild clinical and pathological changes. Virus isolations from the affected joints ceased 15 days after inoculation but continued until day 35 from the caecal tonsil. All inoculated birds developed precipitating antibodies which persisted for at least 46 days.
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PMID:Observations on viral tenosynovitis (viral arthritis) in Scotland. 1877 Apr 3

Brown syndrome fits the group of restrictive strabismus and is caused by a movement limitation of the superior oblique tendon through the trochlea. It is characterized by parallelism in the primary gaze position, limitation or absence of elevation in adduction, frequent depression of the eye in adduction with anisotropy in V-pattern and positive passive duction in the elevation in adduction. It is called inflammatory Brown syndrome, a secondary disorder, which main causes are local inflammation in the orbit and inflammatory diseases such as rheumatoid arthritis and tenosynovitis. A case of a 44 year-old patient, male, complaining of binocular vertical diplopia due to recurring dextroversion is reported. It was diagnosed as inflammatory Brown syndrome of uncertain etiology, confirmed by magnetic nuclear resonance, and with spontaneous resolution.
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PMID:[Inflammatory Brown syndrome: case report]. 2094 46