Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0154059 (Esophagus)
2,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
zinc finger protein 207 13.4
N-myristoyltransferase 2 11.8
squamous cell carcinoma antigen 2 11.4
MAGE-D4 10.4
cysteine dioxygenase type 1 10.1
BRAVO 9.8
C20orf54 9.8
claudin 18 9.5
LDOC1 9.2
annexin A10 9.2
ECRG2 9.1
KE4 9.1
CDO1 8.9
fragile histidine triad gene 8.9
HGD 8.4
TMIE 8.4
HPP1 8.4
Protein kinase D1 8.4
POU3F3 8.3
IMP1 8.2
adenomatosis polyposis coli 8.0
POD1 8.0
PABP2 7.9
CEA mRNA 7.8
phospholipase C epsilon 1 7.8
excision repair cross-complementing 1 7.7
DRC1 7.7
POLB 7.7
Eosinophil-derived neurotoxin 7.6
KRT16 7.6
TEF 7.6
EMP1 7.5
lok 7.5
CBR3 7.5
stem cell growth factor 7.5
DSC2 7.5
POEM 7.5
COL4A6 7.4
GIF 7.4
Astrin 7.4
Gamma-glutamyltransferase 7.4
Eosinophil peroxidase 7.3
cyclin G2 7.3
FAT4 7.3
CDH11 7.3
proton pump 7.1
OPRT 7.1
SEC3 7.1
EMS1 6.9
ribosomal protein L3 6.9
JAM-C 6.9
DYS 6.9
GRP1 6.9
MOR1 6.8
P73 6.8
T-synthase 6.8
SEC1 6.8
UBR1 6.7
Acidic fibroblast growth factor 6.7
CTGF protein 6.7
PTPRD 6.7
secreted frizzled-related protein 1 6.7
squamous cell carcinoma antigen 6.6
ZNF217 6.6
DCI 6.6
ABCC5 6.6
Lipocalin 2 6.6
neural Wiskott-Aldrich syndrome protein 6.6
CD3-epsilon 6.6
DOCK8 6.5
IL12A 6.5
FOXF1 6.5
C30 6.4
CENPF 6.4
aldehyde dehydrogenase 1A1 6.4
SPRY4 6.4
Doublecortin-like kinase 1 6.3
IT1 6.3
RPA1 6.3
CHEK1 6.3
metastasis-associated protein 6.3
pT1 6.3
PT1 6.2
SFRP4 6.2
PREP 6.2
keratin 16 6.1
POR 6.0
FABP5 6.0
GLI2 6.0
MME 6.0
pT3 6.0
human leukocyte antigen class I 6.0
neuronal apoptosis inhibitory protein 5.9
CDC25B 5.9
programmed cell death 4 5.9
COL11A1 5.9
CEACAM6 5.9
Bravo 5.8
Crk-associated substrate 5.8
SCC antigen 5.8
prostaglandin E synthase 5.7
melanoma-associated antigen 5.7
HSP47 5.7
SFRP2 5.7
BAG-1 5.7
NDRG1 5.7
proteinase-activated receptor-2 5.6
ADH1B 5.6
nucleoside phosphorylase 5.6
sex determining region Y 5.6
P210 5.6
RB2 5.6
Cortactin 5.5
ASIC3 5.5
eosinophil major basic protein 5.5
A30 5.5
cystatin A 5.4
necdin 5.4
mucin 2 5.4
EPHX1 5.4
TIMP-4 5.4
GLI3 5.4
MUC6 5.4
ELS 5.3
TNM 5.3
Se2 5.3
CK7 5.3
CD87 5.3
P62 5.3
HIF-1 alpha 5.2
Phosphatase and tensin homolog 5.2
neuromedin B 5.2
villin 5.2
high mobility group box 5.2
DGCR8 5.1
CEACAM1 5.1
IL12B 5.1
COL4A5 5.1
thyroxine-binding prealbumin 5.1
SM3 5.1
RTP 5.0
Methylenetetrahydrofolate reductase 5.0
eosinophil-derived neurotoxin 5.0
pyruvate kinase M2 5.0
DES 5.0
MVD 5.0
nm23-H1 5.0
BCH 4.9
FACT 4.9
MYH9 4.9
REC 4.9
SMARCA4 4.9
GPX2 4.9
P16 4.9
MAPK/ERK kinase 4.8
RASSF1A 4.8
PR1 4.8
TFF2 4.8
protein kinase D 4.8
phosphoglycerate dehydrogenase 4.8
more...
Disease
Malignant esophageal stricture 13.4
Esophagus 13.4
Esophagus 13.4
NEPPK 12.4
Pangastritis 12.4
Esophageal 12.2
stage I esophageal cancer 12.1
Nutcracker esophagus 11.8
Esophageal GIST 11.8
Esophageal leiomyoma 11.3
Drug-induced esophagitis 11.1
Esophageal anastomotic leak 11.1
Esophageal atresia/tracheoesophageal fistula 11.1
Erosive esophagitis 10.5
recurrent esophageal cancer 10.5
Hypopharynx 10.5
Generalized morphea 10.4
Anterior spinal artery syndrome 10.4
metastatic esophageal cancer 10.4
pyloric dysfunction 10.1
connective tissue cancer 9.9
Esophageal rupture 9.9
Schatzki's ring 9.8
postvagotomy syndrome 9.7
Dysphagia lusoria 9.7
esophageal cancer 9.6
esophageal cancer 9.5
Eosinophilic esophagitis 9.5
Reflux esophagitis 9.5
esophageal stricture 9.3
achalasia 9.2
Recurrent laryngeal nerve palsy 9.2
Human papilloma virus infection 9.2
Barrett's esophagus 9.2
esophageal spasm 9.2
Self-induced vomiting 9.2
esophageal dysmotility 9.1
paraesophageal hernia 9.1
Boerhaave's syndrome 9.0
Multiple cancer 8.9
Leiomyomatosis 8.9
Esophageal perforation 8.9
esophageal web 8.9
Alkaline reflux gastritis 8.9
Recurrent cancer 8.8
Esophageal adenocarcinoma 8.8
megaesophagus 8.7
pharyngolaryngitis 8.7
herpes esophagitis 8.7
Heller 8.7
Plummer-Vinson syndrome 8.7
Esophageal tuberculosis 8.6
recurrent laryngeal cancer 8.6
Zenker's diverticulum 8.6
esophageal atresia 8.6
gastroesophageal reflux disease 8.4
esophagitis 8.4
hiatal hernia 8.4
carcinoma of the esophagus 8.4
Esophageal squamous cell carcinoma 8.4
Laryngopharyngeal reflux 8.2
reflux esophagitis 8.2
Vagina 8.2
Brunner's gland hyperplasia 8.0
dysphagia 8.0
aerophagia 7.9
duodenal polyp 7.8
Vagina 7.8
Vulva 7.8
Chemoradiation 7.8
SMA II 7.7
gastrointestinal reflux 7.7
Gastric perforation 7.7
Basaloid squamous cell carcinoma 7.6
premalignant condition 7.6
Lymphatic metastasis 7.4
chronic pharyngitis 7.3
Trachea 7.3
Trachea 7.3
acute thyroiditis 7.3
Johanson-Blizzard syndrome 7.3
Trachea 7.2
Mallory-Weiss syndrome 7.2
oral herpes 7.1
esophageal candidiasis 7.0
tracheomalacia 7.0
esophageal ulceration 6.9
Duodenogastric reflux 6.9
Benign fibrous histiocytoma 6.9
tylosis 6.8
glomangioma 6.8
Fordyce 6.6
VIN 3 6.6
Recurrent disease 6.6
squamous cell carcinoma 6.5
Carcinosarcoma 6.5
Anus 6.4
chest pain syndrome 6.3
Oculopharyngeal muscular dystrophy 6.3
Chronic gastritis 6.3
Jacobsen syndrome 6.3
Lymph node metastases 6.3
Jejunum 6.3
Postoperative infection 6.3
mediastinitis 6.3
Extramammary Paget's disease 6.2
Mucous membrane pemphigoid 6.2
hypopharyngeal cancer 6.2
carditis 6.1
harmful drinking 6.1
Squamous Cell Carcinoma 6.1
Stomach 6.0
Stomach 6.0
Stomach 6.0
gastroparesis 5.9
reactive airway disease 5.9
Stomach 5.9
Bianchi 5.9
bullous dermatoses 5.9
Kugelberg-Welander 5.9
Dubowitz 5.9
Adenocarcinoma 5.8
Globus 5.8
Small cell carcinoma 5.8
Small intestine 5.7
chylothorax 5.7
dysplasia 5.6
dumping syndrome 5.6
leiomyoma 5.6
generalized disease 5.6
adenocarcinoma 5.6
Granular cell tumor 5.6
linitis plastica 5.6
fear of cancer 5.6
gastrointestinal cancer 5.6
pyothorax 5.5
SM1 5.4
Leiomyosarcoma 5.4
primary disorders 5.4
Werdnig-Hoffmann disease 5.3
Chylous ascites 5.3
duodenitis 5.3
angiolipoma 5.3
aspiration pneumonia 5.2
sarcocystosis 5.2
SIRS 5.2
Uterus 5.2
Helicobacter pylori gastritis 5.2
poikiloderma 5.2
toxic nodular goiter 5.2
Cancer cachexia 5.2
Granular cell tumor 5.1
Leiomyoma 5.1
Leiomyoma 5.1
Urbach 5.0
carcinosarcoma 5.0
metastatic osteosarcoma 5.0
glossitis 5.0
TRS 5.0
Helicobacter pylori infection 4.9
more...
Symptom
Tongue fasciculations 11.1
Throat symptoms 10.2
Globus sensation 9.9
painful swallowing 8.9
heartburn 8.9
ENT symptoms 7.9
Regurgitation 7.9
belching 7.9
acid regurgitation 7.6
aphagia 6.8
regurgitation 6.6
bradypnea 5.7
aphonia 5.4
chest pain 5.4
retching 5.3
bloating 5.3
Gastrointestinal symptoms 5.2
hoarseness 5.2
Poor sleep 4.9
Respiratory symptoms 4.5
chronic cough 4.4
sore throat 4.3
epigastric pain 4.2
stridor 4.2
Fluctuation 4.2
atypical chest pain 4.1
Wind 4.0
colic 3.8
abdominal discomfort 3.6
cough 3.6
vomiting 3.3
tingling 3.1
discomfort 2.9
cachexia 2.9
paresis 2.9
acidity 2.8
discomfort 2.8
acute abdomen 2.8
wheezing 2.8
nausea 2.7
shortness of breath 2.6
overweight 2.6
incoordination 2.6
cyanosis 2.5
nausea and vomiting 2.5
anorexia 2.5
rhinorrhea 2.2
dyspnea 2.2
constipation 2.1
abdominal pain 2.1
asthenia 2.0
ENT 2.0
respiratory distress 1.9
erythema 1.7
ophthalmoplegia 1.7
spasm 1.5
pain 1.5
anesthesia 1.5
analgesia 1.2
fatigue 1.2
diarrhea 1.2
insomnia 1.0
hunger 0.9
lethargy 0.9
back pain 0.8
hemoptysis 0.8
flushing 0.8
sleepiness 0.8
arthralgia 0.6
dizziness 0.2
weakness -0.2
stigma -0.3
exhaustion -0.3
collapse -0.4
ataxia -0.6
hypothermia -0.7
headache -2.4
seizures -2.9
Drug
Sivelestat sodium hydrate 9.8
Sivelestat 8.8
Histalog 8.5
Polaprezinc 8.4
EVM 8.3
Histalog 8.3
Lugol 8.1
Lugol's solution 8.0
CEG 7.9
CEG 7.7
BOTOX 7.0
Tenoxicam 6.4
Lipidex 5.8
Flavopiridol 5.7
Mitomycin-C 5.7
Sodium alginate 5.5
Omeprazole 5.4
Propidium 5.4
Areca 5.3
Nimesulide 5.2
Cisapride 5.0
Botox 4.7
Gastro 4.6
CSI 4.5
Digenea 4.1
Digitalis 4.1
Triad 4.1
Triad 4.0
Paraffin 3.9
Erlotinib 3.8
Irinotecan 3.7
Photofrin 3.6
Cetuximab 3.5
Gefitinib 3.2
Vitamin B12 3.1
CoCl2 3.1
CoCl2 3.1
Methylene blue 3.1
CTA 2.9
Prednisolone 2.9
Simvastatin 2.7
Docetaxel 2.6
Herceptin 2.2
Ouabain 2.1
Indomethacin 1.8
HCH 1.6
PCP 1.5
Glucagon 1.5
Fluorescein 1.5
niacin 1.5
ROC 1.5
p75 1.5
Spectrum 1.5
ENT 1.3
ABC 1.3
Albumin 1.2
Glutathione 1.0
Histamine 1.0
ascorbate 0.9
CAM 0.9
vitamin E 0.3
citric acid 0.1
Leaf -0.0
Asthma -0.3
Gel -0.5
caffeine -1.0
Monit -1.7
lysine -2.4
Dermatol -4.6
Enzyme
homoserine kinase 6.4
matriptase 4.9
dihydropyrimidine dehydrogenase 4.7
dihydropyrimidine dehydrogenase 4.7
matriptase 4.4
thymidine phosphorylase 4.4
TRS 4.4
thromboxane synthase 4.3
CDH 4.2
AGT 3.8
MCS 3.8
microsomal epoxide hydrolase 3.8
sucrase-isomaltase 3.6
DCF 3.5
sucrase 3.2
chymase 3.0
neutrophil elastase 3.0
LPL 3.0
tryptase 3.0
aldehyde dehydrogenase 2.9
aldehyde dehydrogenase 2.9
aldehyde dehydrogenase 2.9
aldehyde dehydrogenase 2.6
AOR 2.6
thymidylate synthase 2.6
aldehyde dehydrogenase 2.3
PDK1 2.3
matrix metalloproteinase 2 2.2
pepsin 1.9
reverse transcriptase 1.6
enolase 1.5
PCP 1.5
NADPH-diaphorase 1.5
MMP 1.3
transcriptase 1.2
transglutaminase 1.2
invertase 1.1
DNA methyltransferase 1.1
PARP 0.7
caspase-8 0.7
urease 0.6
NOS 0.6
urease 0.5
NO synthase 0.5
guanylate cyclase 0.3
ERK 0.3
gamma-glutamyl transpeptidase 0.3
elastase 0.2
alcohol dehydrogenase 0.2
glutathione reductase 0.2
caspase-3 -0.1
phospholipase A2 -0.4
APC -0.6
DNA polymerase -0.7
RNA polymerase -0.7
ACE -0.8
catalase -0.8
creatine kinase -0.8
mitogen-activated protein kinase -0.8
trypsin -1.0
peroxidase -1.0
glutathione peroxidase -1.0
acetylcholinesterase -1.4
ATPase -1.6
thrombin -1.6
protein kinase -1.9
focal adhesion kinase -2.0
alkaline phosphatase -2.1
protein kinase C -2.2
superoxide dismutase -2.4
Compound
Benazepril 7.3
D 3 6.9
DCI 6.6
APO 6.2
Paeonol 6.0
OMPA 5.9
barium 5.7
Triamcinolone 5.5
Ephedrine 5.3
TNM 5.3
Montelukast 5.2
Paeoniflorin 5.2
Omeprazole 5.1
TEG 5.0
Cisapride 5.0
MME 5.0
PPI 5.0
DES 4.9
TBE 4.8
Sumatriptan 4.8
Terbutaline 4.8
SCC 4.7
CBDCA 4.5
CBDCA 4.5
Buspirone 4.5
Alginate 4.4
BHC 4.4
Tetrahydrocannabinol 4.3
Baclofen 4.2
Deoxyribonucleic acid 4.1
Ach 4.1
CDH 4.1
ACNU 4.1
DEN 4.0
Apigenin 3.8
DCA 3.8
DCA 3.8
DOP 3.8
malonic acid 3.7
SITS 3.6
MAL 3.6
Celecoxib 3.5
5-FU 3.4
Eosin 3.4
Hypo 3.4
A 71 3.3
HCI 3.2
HEPES 3.1
Eosin 3.1
Risperidone 3.1
Luminal 3.1
Statin 3.1
Hematoxylin 3.1
DIC 3.0
MCH 3.0
Docetaxel 3.0
Formal 3.0
Prednisolone 2.9
COX 2.8
VP-16 2.8
folinic acid 2.7
MMA 2.7
Flux 2.6
Methylene blue 2.5
Estrogen 2.5
PGD2 2.5
DOCA 2.5
Piper 2.4
ITP 2.4
TXA2 2.3
Fibrin 2.3
MMA 2.2
Ouabain 2.1
DDP 2.1
Thromboxane 2.1
Vimentin 2.1
MTS 2.0
Fibrinogen 2.0
MMC 2.0
Nifedipine 1.9
Methicillin 1.8
ASA 1.8
A 1 1.8
8-OHdG 1.7
Serine 1.7
Heme 1.6
Glucagon 1.5
A 3 1.5
Prostaglandin 1.5
Prostaglandin 1.5
dUTP 1.5
Salix 1.4
THE 1.4
Salt 1.3
Optimal 1.3
PCP 1.3
dicarboxylic acid 1.2
Panam 1.2
Nitrate 1.1
MTT 1.0
N-acetylcysteine 1.0
Histamine 0.9
Ascorbic acid 0.9
ADP-ribose 0.9
ADR 0.8
diacetate 0.8
iodine 0.6
6-12 0.6
acridine 0.6
prostaglandin E1 0.6
H2S 0.4
Adriamycin 0.4
alcohol dehydrogenase 0.3
ClO 0.3
PGE 0.3
CAT 0.3
CAT 0.3
HCl 0.2
vitamin D 0.2
aluminum 0.2
CAT 0.2
formaldehyde 0.1
Cholesterol 0.1
CAM 0.1
phosphoric acid 0.1
Estrogen 0.1
anthracene 0.1
urea 0.0
DBA -0.1
CO2 -0.3
DNA -0.3
cobalt -0.4
bromide -0.4
PGE2 -0.4
water -0.5
potassium -0.6
arginine -0.6
chlorine -0.6
Pac -0.6
acetic acid -0.7
His -0.9
nitric oxide -0.9
creatinine -0.9
sodium -0.9
pyrimidine -0.9
TNF -0.9
TOF -0.9
pyrimidine -0.9
Ile -0.9
GSH -0.9
GSH -1.0
cGMP -1.0
caffeine -1.0
selenium -1.1
oxygen -1.1
retinoic acid -1.2
hydroxide -1.2
nitrogen -1.3
DSM -1.3
glutamine -1.3
more...