Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0154059 (Esophagus)
 2,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Relative incidences of esophagus, lung and breast cancers differ in the various populations in Kyrgyzstan. Esophagus cancer is the most commonly observed among the Turkic groups, especially in Kazakhs, while lung and breast cancer are frequently encountered among the European representatives of the population - Russians in particular. Fluctuation in rates for these cancer forms in the Kyrgyzstan mountain regions is highly dependable on the height above sea level. One potential major factor, which may account for the low cancer frequency in general and influence esophagus, lung and breast cancer forms in particular - is mountain hypoxia. Since, among the native citizens (Kyrgyzes), which are adapted to mountain hypoxia conditions (population adaptation), the indicated cancer forms are not so often than the same forms appearance among the other ethnical groups (long adaptation), especially newcoming ones. Thus, the incidence rates of esophageal cancer in the Kazakh population is about 32,3 (per 100,000), the same sickness in Kyrgyz is about 11,3, the figure for lung cancer among the Russian population is 34,8, while among Kyrgyzes it is 11,2, breast cancer incidence in Russian citizens is 34,8 but only15,1 among Kyrgyz residents. It could be established that the studied forms of cancer are less common in high mountain regions than in the regions with low mountains. To a certain extent, mountain hypoxia may function like a brake for the development of cancer tumors. HGowever, the situation is complex, because of, the presence of the other factors entailed by the demographic, social-economic and other variation.
Asian Pac J Cancer Prev 2002
PMID:Epidemiology of Esophagus, Lung and Breast Cancer in Mountainous Regions of Kyrgyz Republic. 1271 12

There are no population-based data available on cancer pattern in Kashmir and our study is the first kind which represents the trend in cancer pattern in the valley. The source of our data were cancer patients registered in the Department of Radiation Oncology, Sheri-Kashmir Institute of Medical Sciences, Srinagar, and Department of Radiation Oncology, SMHS, Srinagar during the period Jan 2002 to Dec 2006. These are leading medical centres in the valley and draw most all of cancer patients from all over Kashmir for treatment. During the period a total of 6,943 cases were registered of which 4,345 were males and 2,598 were females. The age standardized incidence rates were 34.9 per 100,000 for males and 24.8 per 100,000 for females. Oesophagus was the leading site of cancer in both sexes (male ASR 11.2; female ASR 8.3) followed by lung (ASR 6.5), brain (ASR 2.2) and head and neck (ASR 2.2) in males and breast (ASR 5.2), skin (ASR 1.6) and rectum (ASR 0.95) in females. The incidence of cervical cancer in females and prostate cancer in males was lower in Kashmir as compared to other Indian registries. Overall cancer incidence was significantly lower and cancer patterns were markedly different in Kashmir. The observed cancer pattern indicates that awareness campaigns, life style and dietary habit changes, tobacco-control measures and early detection of breast cancer are very important for cancer control in this population.
Asian Pac J Cancer Prev 2011
PMID:Epidemiological distribution and incidence of different cancers in Kashmir valley--2002-2006. 2212 81