Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0153690 (bone metastases)
6,382 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 388 alkaline phosphatase 240 Mol 191 MRI 182 prostate-specific antigen 156 She 141 RANKL 141 parathyroid hormone-related protein 134 FDG 123 RANK 105 PSA 97 MDP 89 collagen 86 type I collagen 84 parathyroid hormone 82 osteosarcoma 82 osteoprotegerin 79 cytokine 72 estrogen receptor 62 nodal 62 prostate specific antigen 61 osteocalcin 61 calcitonin 60 androgen receptor 58 tyrosine kinase 56 HER2 54 vascular endothelial growth factor 52 epidermal growth factor receptor 51 CEA 48 aromatase 48 PC3 47 PC-3 47 acid phosphatase 46 prostate-specific membrane antigen 44 thyroglobulin 41 prostatic acid phosphatase 40 carcinoembryonic antigen 38 somatostatin 37 EGFR 36 tartrate-resistant acid phosphatase 35 p53 35 cathepsin K 34 osteogenic 31 PTH 30 cage 30 osteopontin 29 progesterone receptor 28 OPG 27 interleukin-6 26 cytokeratin 26 MMP-9 26 MET 25 TNM 24 interferon 24 mTOR 24 matrix metalloproteinase 24 IL-6 24 phosphatase 23 receptor activator of NF-kappaB ligand 23 Men 23 bone) 23 vimentin 22 ALP 22 E-cadherin 22 hemoglobin 22 lactate dehydrogenase 22 LHRH 22 PSMA 21 bone sialoprotein 21 endothelin-1 21 chromogranin A 21 CXCR4 21 VEGF 20 parathormone 20 p38 20 CA15 20 rhabdomyosarcoma 19 type I procollagen 19 Dickkopf-1 19 CD44 19 more...

Disease bone metastases 6382 cancer 2546 metastases 2424 tumor 1980 breast cancer 1475 prostate cancer 1376 carcinoma 700 hypercalcemia 445 bone disease 390 lung cancer 310 multiple myeloma 275 osteoporosis 263 primary tumor 247 adenocarcinoma 242 spinal cord compression 229 metastatic breast cancer 206 renal cell carcinoma 187 tumor growth 179 liver metastases 171 pathological fracture 157 lung metastases 153 tumor progression 136 melanoma 109 brain metastases 108 PSA 97 hepatocellular carcinoma 97 osteosarcoma 94 non-small cell lung cancer 92 gastric cancer 85 thyroid cancer 84 Prostate Cancer 84 squamous cell carcinoma 75 PDB 73 lung carcinoma 70 neuroblastoma 67 hypercalcemia of malignancy 62 sarcoma 61 prostatic adenocarcinoma 56 anemia 51 bone cancer 47 renal cancer 44 tumorigenesis 43 thrombocytopenia 43 colorectal cancer 40 small cell lung cancer 40 MCF 39 myelosuppression 39 hyperparathyroidism 38 primary hyperparathyroidism 37 metastatic renal cell carcinoma 37 lymphoma 37 carcinoid 36 disseminated intravascular coagulation 35 carcinomatosis 35 aggressiveness 34 carcinoma of the breast 33 Ewing's sarcoma 33 WT1 31 carcinogenesis 31 bladder cancer 30 pheochromocytoma 30 carcinoma of the breast 29 recurrent breast cancer 27 medullary thyroid carcinoma 27 rheumatoid arthritis 27 bone marrow metastases 26 renal failure 25 ductal carcinoma 24 solid tumor 24 adenoma 24 lymphadenopathy 23 residual disease 22 bronchogenic carcinoma 22 paraganglioma 22 colon cancer 22 neutropenia 21 leukemia 21 SCID 21 leukopenia 20 chronic pain 20 more...

Symptom pain 1125 bone pain 422 back pain 54 nausea 54 analgesia 45 cancer pain 42 fatigue 40 headache 37 vomiting 36 dyspnea 34 weakness 28 diarrhea 28 low back pain 26 nausea and vomiting 22 anorexia 20 cough 19 anesthesia 17 cachexia 16 collapse 16 abdominal pain 15 discomfort 13 discomfort 13 chest pain 12 constipation 11 numbness 10 myalgia 8 shortness of breath 8 hip pain 8 dizziness 8 breakthrough pain 8 chills 7 shoulder pain 7 hepatomegaly 7 paresis 7 Ill 7 erythema 7 neck pain 7 hemoptysis 6 tremor 6 epigastric pain 6 sleepiness 6 hypothermia 5 hot flashes 5 lethargy 5 polyuria 5 flank pain 5 knee pain 5 arthralgia 5 asthenia 5 acute pain 5 polydipsia 4 paresthesia 4 Flare 4 dysuria 4 abdominal discomfort 3 leg edema 3 paraparesis 3 leg pain 3 arm pain 3 spasm 3 pelvic pain 3 splenomegaly 3 exertional dyspnea 3 respiratory distress 3 ophthalmoplegia 3 flushing 3 dysarthria 3 abdominal fullness 3 hot flushes 2 thinning 2 halitosis 2 heartburn 2 productive cough 2 syncope 2 tingling 2 Cushingoid 2 consciousness disturbance 2 prostatism 2 sciatica 2 wrist pain 2 more...

Drug Zoledronic acid 154 Zoledronic acid 138 Denosumab 91 EHDP 41 PTH 30 CTX 23 Docetaxel 22 Ibandronate 21 Clodronate 21 CTX 19 APD 19 CTX 19 Adriamycin 18 IL-2 16 Leaf 14 MAP 13 Aredia 13 Cardiovasc 13 SrCl2 12 DMSA 12 CSF 10 IL-11 9 Gefitinib 9 ROC 9 CPT-11 8 ADM 8 Dermatol 8 lysine 7 Imatinib 7 Monit 6 Gallium nitrate 5 ENT 5 Sorafenib 5 HCG 4 Salmon calcitonin 4 ETA 4 Bonefos 3 Leucovorin 3 Gleevec 3 NVP 3 Bayer 3 uPA 3 Vinorelbine 3 Herceptin 3 Dasatinib 3 Arimidex 3 Estrogens 3 EPI 3 Thyroglobulin 3 Everolimus 3 EE2 3 ROS 3 Quadramet 3 Estracyt 3 Estracyt 3 Erlotinib 3 Etoposide 2 Diamminedichloroplatinum 2 CPM 2 ascorbate 2 Paraffin 2 Epidoxorubicin 2 ICI 2 G-CSF 2 Zoladex 2 Albumin 2 Gel 2 Norplant 2 Sandostatin LAR 2 Taxol 2 CTC 2 ProstaScint 2 Nephron 2 Pertuzumab 2 DM1 2 CTC 2 Gelatin 2 Orion 2 SrCl2 2 Lipiodol 2 more...

Enzyme alkaline phosphatase 240 ERK 160 prostate-specific antigen 146 MDP 89 prostate-specific membrane antigen 55 acid phosphatase 46 mitogen-activated protein kinase 35 cathepsin K 34 focal adhesion kinase 31 luciferase 29 lactate dehydrogenase 25 urokinase-type plasminogen activator 13 protein kinase 11 reverse transcriptase 10 MMP 9 caspase-3 9 collagenase 9 MEK 8 ATPase 7 dihydropyrimidine dehydrogenase 6 phosphatidylinositol 3-kinase 6 cathepsin B 6 gamma-glutamyl transpeptidase 6 proteasome 5 MIP 5 lysyl oxidase 5 MMP-3 5 aldehyde dehydrogenase 4 PAL 4 trypsin 4 aldehyde dehydrogenase 4 PAL 4 PARP 4 aldehyde dehydrogenase 4 cdc2 4 aldehyde dehydrogenase 4 firefly luciferase 4 matrix metalloproteinase 9 4 aldehyde dehydrogenase 4 calcineurin 3 neuraminidase 3 aspartate aminotransferase 3 thrombin 3 catalase 3 alanine aminotransferase 3 diamine oxidase 3 monoamine oxidase 3 type III procollagen 3 protein kinase C 3 ACS 2 FAST 2 PMT 2 glyceraldehyde-3-phosphate dehydrogenase 2 PTR 2 tryptase 2 thyroid peroxidase 2 matriptase 2 sialidase 2 IKK 2 BMT 2 topoisomerase 2 CPM 2 CaMKII 2 CD10 2 plasmin 2 APC 2 creatine kinase 2 ALDH 2 cathepsin D 2 DNA methyltransferase 2 RNase 1 lactic acid dehydrogenase 1 proteinase A 1 prostaglandin synthetase 1 HDR 1 neutrophil elastase 1 MAT 1 succinate dehydrogenase 1 PRA 1 sarcosine dehydrogenase 1 more...

Compound Clin 813 Dec 454 calcium 335 MDA 192 strontium 100 DNA 76 nitrogen 76 creatinine 75 iodine 63 phosphate 61 acetate 61 vitamin D 58 sodium 41 fluorine 37 EHDP 37 methionine 37 tyrosine 36 Pamidronate 35 His 33 water 31 5-FU 30 phosphorus 30 Androgen 30 glucose 26 Adriamycin 26 TNM 24 CTX 23 galactose 22 ALP 22 Docetaxel 21 Thyroid 20 NH2 16 oxygen 16 Asp 15 DTPA 15 cAMP 14 A 71 14 AMP 13 arginine 13 ATP 13 PEG 12 PAP 12 PAP 12 PAP 12 PAP 12 MAP 12 TNF 12 TSH 11 Tamoxifen 11 Tamoxifen 11 nitrate 11 Calcitonin 11 DIC 11 Progesterone 11 MPA 10 FTA 10 MPA 10 MPA 10 ACTH 10 lysine 10 Optimal 10 PEG 9 cysteine 9 BMD 9 CAP 9 CAM 9 TPA 8 leucine 8 CPT-11 8 ADR 8 TPA 8 aspartic acid 8 Gly 8 aspartic acid 8 aspartic acid 8 EDTA 8 urea 8 aspartic acid 8 EDTA 8 Pac 7 more...

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