Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0153690 (bone metastases)
6,382 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 388 alkaline phosphatase 240 Mol 191 MRI 182 prostate-specific antigen 156 She 141 RANKL 141 parathyroid hormone-related protein 134 FDG 123 RANK 105 PSA 97 MDP 89 collagen 86 type I collagen 84 parathyroid hormone 82 osteosarcoma 82 osteoprotegerin 79 cytokine 72 nodal 62 estrogen receptor 62 osteocalcin 61 prostate specific antigen 61 calcitonin 60 androgen receptor 58 tyrosine kinase 56 HER2 54 vascular endothelial growth factor 52 epidermal growth factor receptor 51 CEA 48 aromatase 48 PC-3 47 PC3 47 acid phosphatase 46 prostate-specific membrane antigen 44 thyroglobulin 41 prostatic acid phosphatase 40 carcinoembryonic antigen 38 somatostatin 37 EGFR 36 tartrate-resistant acid phosphatase 35 more...

Disease bone metastases 6382 cancer 2546 metastases 2424 tumor 1980 breast cancer 1475 prostate cancer 1376 carcinoma 700 hypercalcemia 445 bone disease 390 lung cancer 310 multiple myeloma 275 osteoporosis 263 primary tumor 247 adenocarcinoma 242 spinal cord compression 229 metastatic breast cancer 206 renal cell carcinoma 187 tumor growth 179 liver metastases 171 pathological fracture 157 lung metastases 153 tumor progression 136 melanoma 109 brain metastases 108 PSA 97 hepatocellular carcinoma 97 osteosarcoma 94 non-small cell lung cancer 92 gastric cancer 85 thyroid cancer 84 Prostate Cancer 84 squamous cell carcinoma 75 PDB 73 lung carcinoma 70 neuroblastoma 67 hypercalcemia of malignancy 62 sarcoma 61 prostatic adenocarcinoma 56 anemia 51 bone cancer 47 more...

Symptom pain 1125 bone pain 422 back pain 54 nausea 54 analgesia 45 cancer pain 42 fatigue 40 headache 37 vomiting 36 dyspnea 34 diarrhea 28 weakness 28 low back pain 26 nausea and vomiting 22 anorexia 20 cough 19 anesthesia 17 cachexia 16 collapse 16 abdominal pain 15 discomfort 13 discomfort 13 chest pain 12 constipation 11 numbness 10 shortness of breath 8 breakthrough pain 8 dizziness 8 myalgia 8 hip pain 8 shoulder pain 7 erythema 7 paresis 7 chills 7 hepatomegaly 7 neck pain 7 Ill 7 hemoptysis 6 tremor 6 sleepiness 6 more...

Drug Zoledronic acid 154 Zoledronic acid 138 Denosumab 91 EHDP 41 PTH 30 CTX 23 Docetaxel 22 Clodronate 21 Ibandronate 21 APD 19 CTX 19 CTX 19 Adriamycin 18 IL-2 16 Leaf 14 MAP 13 Cardiovasc 13 Aredia 13 DMSA 12 SrCl2 12 CSF 10 ROC 9 IL-11 9 Gefitinib 9 Dermatol 8 ADM 8 CPT-11 8 lysine 7 Imatinib 7 Monit 6 Sorafenib 5 Gallium nitrate 5 ENT 5 ETA 4 HCG 4 Salmon calcitonin 4 EE2 3 Thyroglobulin 3 Leucovorin 3 Estracyt 3 more...

Enzyme alkaline phosphatase 240 ERK 160 prostate-specific antigen 146 MDP 89 prostate-specific membrane antigen 55 acid phosphatase 46 mitogen-activated protein kinase 35 cathepsin K 34 focal adhesion kinase 31 luciferase 29 lactate dehydrogenase 25 urokinase-type plasminogen activator 13 protein kinase 11 reverse transcriptase 10 caspase-3 9 collagenase 9 MMP 9 MEK 8 ATPase 7 cathepsin B 6 dihydropyrimidine dehydrogenase 6 gamma-glutamyl transpeptidase 6 phosphatidylinositol 3-kinase 6 proteasome 5 lysyl oxidase 5 MMP-3 5 MIP 5 matrix metalloproteinase 9 4 PAL 4 aldehyde dehydrogenase 4 aldehyde dehydrogenase 4 aldehyde dehydrogenase 4 aldehyde dehydrogenase 4 trypsin 4 PARP 4 cdc2 4 aldehyde dehydrogenase 4 PAL 4 firefly luciferase 4 monoamine oxidase 3 more...

Compound Clin 813 Dec 454 calcium 335 MDA 192 strontium 100 nitrogen 76 DNA 76 creatinine 75 iodine 63 phosphate 61 acetate 61 vitamin D 58 sodium 41 EHDP 37 fluorine 37 methionine 37 tyrosine 36 Pamidronate 35 His 33 water 31 5-FU 30 Androgen 30 phosphorus 30 glucose 26 Adriamycin 26 TNM 24 CTX 23 ALP 22 galactose 22 Docetaxel 21 Thyroid 20 oxygen 16 NH2 16 DTPA 15 Asp 15 A 71 14 cAMP 14 AMP 13 arginine 13 ATP 13 more...

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