Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0153690 (
bone metastases
)
6,382
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two cases with osteolytic
bone metastases
from cervical cancer and esophageal cancer treated by local therapy were reported. The first case is a 53-year-old female with
bone metastases
of left ischium developed 1 year after hysterectomy. She was treated by intratumor injection of sizofiran (
SPG
) 20 mg/w and radiation therapy. After 4 weeks, ischias pain decreased and bone lesion showed remarkable calcification (PR) 8th months later. The second case is a 58-year-old male with
bone metastases
of the left tibia and fibula developed 1 year after surgery. He was treated by intratumor injection of
SPG
20 mg/w x 4 and OK-432 1.0 KE/w x 8 after radiation therapy. After 4 weeks, pain and swelling of left leg decreased and bone lesions showed remarkable calcification (PR) three months later. We suggest that intratumor injection of
SPG
and OK-432 with radiation therapy was effective for osteolytic
bone metastases
.
...
PMID:[Two cases of cancer with bone metastases treated with local therapy]. 837 57
