Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0153640 (Cerebellum)
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Human Gene/Protein
KIAA0960 14.1
SYNE1 protein 14.1
zinc finger protein 4 13.1
CAPS2 protein 13.1
ITPR1 protein 12.5
Thg-1pit 12.5
KIAA0226 12.1
SCA10 11.5
FERD3L 11.5
EEFSEC 11.3
SCA17 11.2
TSC22D4 11.1
PHAP I 11.1
ATXN7 11.1
SCA12 11.1
ANO10 11.0
anoctamin 2 11.0
SCA5 11.0
SPTBN2 10.9
SCA7 10.9
MAST4 10.8
PHF14 10.7
SCA1 10.6
SCA3 10.5
SCA11 10.5
carbonic anhydrase-related protein 10.5
SCA2 10.5
KCNC3 10.5
LAF4 10.5
SARA 10.5
excitatory amino acid transporter 4 10.4
WDR81 10.4
TOE1 10.3
PTPRR 10.3
B3GALNT2 10.2
protocadherin 10 10.2
ATXN10 10.1
Spinocerebellar ataxia type 7 10.1
CDG Ia 10.0
ATXN3 10.0
SCA8 10.0
spinocerebellar ataxia type 2 10.0
SCA6 10.0
ataxin 2 9.9
AFG3L2 9.9
ATXN1 9.9
Munc13-3 9.8
AARS2 9.8
PEP-19 9.7
GAA1 9.7
KCND3 9.6
CA-RP XI 9.6
CAPS1 9.6
phocein 9.6
DGKB 9.5
puratrophin-1 9.5
ATXN2 9.5
DRPLA 9.5
PPP2R2C 9.5
PDSS2 9.5
SG2NA 9.5
senataxin 9.4
CRAG 9.4
LCA2 9.4
ataxin-1 9.4
ANP32B 9.4
TBP protein 9.3
CADPS2 9.3
ITPR1 9.3
TSA-1 9.2
KCNJ12 9.2
PTP-SL 9.2
CAPS2 9.1
FARS 9.1
CA8 9.1
FGF14 9.0
CA11 9.0
NOP56 9.0
neurochondrin 9.0
SPG7 8.9
more...
Disease
Cerebral ataxia 14.1
Cerebellar Glioblastoma Multiforme 14.1
Cerebellum 14.1
SCA23 12.1
Progressive cerebellar ataxia 12.1
SCA18 12.1
Rebound nystagmus 12.0
SCA25 11.8
SCAR8 11.8
SCA19 11.8
Brainstem compression 11.8
SCA20 11.8
SCA14 11.8
SCA21 11.5
SCA5 11.3
SCA13 11.2
SCA6 11.2
SCA17 11.2
SCA16 11.1
SCA12 11.1
SCA11 11.0
SCA7 10.8
SCA27 10.7
Spinocerebellar ataxia 10.6
SCA1 10.5
SCA2 10.5
Vertical nystagmus 10.3
Neuhauser syndrome 10.2
SCA15 10.2
Machado-Joseph disease 10.1
Fetal asphyxia 10.0
Age-associated memory impairment 10.0
Gaze-evoked nystagmus 9.9
SCA8 9.8
writing disorder 9.8
SCA4 9.7
Progressive myoclonic epilepsy 9.7
alcoholic cerebellar degeneration 9.3
cerebellar syndrome 9.3
AOA2 9.2
Medulla 9.2
Downbeat nystagmus 9.1
Angiomatosis 9.1
Cerebellar atrophy 9.0
Essential tremor 8.9
Friedreich's ataxia 8.9
SPG7 8.8
FRDA 8.8
hereditary ataxia 8.8
Speech impairment 8.8
progressive chorea 8.7
Paraneoplastic cerebellar degeneration 8.6
FXTAS 8.6
SACS 8.5
Opsoclonus-myoclonus syndrome 8.4
Crush syndrome 8.2
AGS3 8.1
Fukuyama congenital muscular dystrophy 8.0
olivopontocerebellar atrophy 7.8
Salla disease 7.7
agrammatism 7.6
Viral myocarditis 7.5
Joubert syndrome 7.5
Kufs' disease 7.4
SCP 7.3
REM sleep behavior disorder 7.3
blunted affect 7.3
hypotropia 7.2
MSA 7.2
FRAXE 7.2
exophoria 7.2
SBMA 7.1
sialidosis 7.0
Multiple system atrophy 7.0
embryonal tumor 7.0
compulsive personality disorder 7.0
mutism 6.8
Dandy-Walker malformation 6.8
CM1 6.7
Dystonia 6.7
more...
Symptom
poor balance and coordination 11.5
Limb ataxia 11.0
Apraxic 9.7
Ataxic 9.6
Pyramidal signs 9.5
cerebellar ataxia 9.4
Postural tremor 9.0
ataxia 8.9
abiotrophy 8.8
intention tremor 8.3
Cervical dystonia 7.5
ataxic gait 7.3
dysarthria 7.2
stump pain 7.2
astasia 7.2
loss of balance 6.9
frequent urination 6.7
clumsiness 6.6
Neurologic symptoms 6.6
impaired motor coordination 6.5
Extrapyramidal symptoms 6.5
giddiness 6.5
tremor 6.5
giddiness 6.5
incoordination 6.1
chorea 6.1
dystonia 6.1
Psychiatric symptoms 5.8
abnormal gait 5.6
myoclonus 5.4
muscle cramps 5.3
vertigo 5.1
ophthalmoplegia 5.0
urinary frequency 5.0
bradykinesia 4.9
partial seizure 4.7
spasticity 4.6
alexithymia 4.4
neurological disability 4.3
hypotonia 4.2
blepharospasm 4.1
apathy 4.1
eds 4.1
dizziness 3.9
asthenia 3.8
Sedation 3.7
anosmia 3.6
neuralgia 3.4
memory loss 3.3
Depressive symptoms 3.2
hemiplegia 3.2
chronic cough 3.1
twitching 3.1
paresthesia 2.9
pallor 2.8
tachypnea 2.8
hypercapnia 2.8
insomnia 2.8
paraparesis 2.7
snoring 2.6
sleepiness 2.5
tinnitus 2.4
seizures 2.2
functional recovery 2.0
paresis 1.6
agitation 1.6
anorexia 1.4
fatigue 1.3
weakness 1.2
starvation 1.1
headache 0.9
constipation 0.8
vomiting 0.8
Ill 0.7
discomfort 0.7
thinning 0.7
cough 0.6
discomfort 0.6
anesthesia 0.5
collapse 0.3
more...
Drug
Omniscan 7.0
Modafinil 5.5
AGG 5.5
Frontal 5.4
DFP 5.3
TMS 5.3
Valsartan 5.2
Orphan 5.1
Ethanol 4.3
Adenosine triphosphate 4.3
Reserpine 4.2
DPA 3.8
CTA 3.7
DM1 3.5
Ranitidine 3.5
Fructose 3.2
p75 3.2
Check 3.2
Paraffin 3.0
CDP 2.9
Nitric Oxide 2.8
AZT 2.7
Histamine 2.7
AZT 2.6
Indomethacin 2.5
Kenyan 2.4
PCP 2.3
ROC 2.2
ABC 2.0
Posture 1.7
EE2 1.2
DNase I 1.1
citric acid 0.9
CSF 0.8
NADH 0.7
IL-2 0.3
Gel 0.3
MAP 0.2
vitamin E 0.0
ROS -0.1
caffeine -0.3
lysine -1.7
Enzyme
triokinase 9.0
m-AAA protease 8.6
ketohexokinase 8.4
UDP-galactose:ceramide galactosyltransferase 8.2
arylsulfate sulfotransferase 7.8
CDP-diacylglycerol synthase 7.5
SCP 7.3
VOR 6.8
alanyl-tRNA synthetase 6.4
sphingomyelin synthase 6.2
6-phosphofructo-2-kinase 5.8
inositol phosphatase 5.7
sulfite oxidase 5.3
sulfite oxidase 5.2
monoacylglycerol lipase 4.7
mu-calpain 4.7
sphingosine kinase 4.6
GABA transaminase 4.5
TSA 3.9
DAT 3.6
protein phosphatase 2A 3.6
paraoxonase 3.4
aldolase 3.4
aconitase 3.4
NOS 3.3
TdT 3.2
glutaminase 3.2
CaMKII 3.2
paraoxonase 3.1
histone acetyltransferase 2.7
5'-nucleotidase 2.5
sulfatase 2.5
caspase-8 2.4
tyrosine hydroxylase 2.3
PDE 2.3
caspase-9 2.3
PCP 2.3
glucose-6-phosphate dehydrogenase 2.2
NADPH-diaphorase 2.2
proteinase K 2.1
proteasome 2.1
glutamate dehydrogenase 2.0
glyceraldehyde-3-phosphate dehydrogenase 2.0
glutamate dehydrogenase 2.0
glyceraldehyde-3-phosphate dehydrogenase 2.0
glutamate dehydrogenase 2.0
citrate synthase 2.0
phospholipase C 2.0
glyceraldehyde-3-phosphate dehydrogenase 1.9
glutathione reductase 1.9
glutamine synthetase 1.8
pyruvate kinase 1.8
CPR 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.7
dihydrofolate reductase 1.6
diaphorase 1.6
glyceraldehyde-3-phosphate dehydrogenase 1.5
aldehyde dehydrogenase 1.5
GSK 1.4
caspase-3 1.3
glutathione peroxidase 1.3
MAP 1.3
NO synthase 1.2
protein kinase C 1.1
cdc2 1.1
calcineurin 1.1
cytochrome oxidase 1.0
phosphodiesterase 0.9
urokinase-type plasminogen activator 0.7
ATPase 0.7
catalase 0.7
superoxide dismutase 0.6
cholinesterase 0.5
acid phosphatase 0.5
P-glycoprotein 0.4
protein kinase 0.4
PARP 0.4
acetylcholinesterase 0.3
phospholipase A2 0.3
creatine kinase -0.1
more...
Compound
DFH 9.6
Harmaline 9.0
BNS 8.4
DBN 8.3
Gadodiamide 8.1
IDPN 7.8
Phytanic acid 7.8
DHM 7.3
MOCA 7.3
Cuprizone 7.2
Allopregnanolone 7.1
Diisopropyl 7.0
Allopregnanolone 6.9
Tiagabine 6.8
DHI 6.8
Sulfamethazine 6.6
fructose-1-phosphate 6.6
CAA 6.1
Taurocholate 6.0
DCB 5.7
MCP 5.5
Riluzole 5.5
CDT 5.4
Pyruvate kinase 5.4
HCP 5.3
Flumazenil 5.2
Nitro-L-arginine 5.2
HCP 5.1
N-acetylaspartate 5.0
Astaxanthin 5.0
MEGA 4.9
Hoe 4.9
LTD 4.9
Ach 4.8
TBP 4.7
DHPG 4.7
Chlorpyrifos 4.6
ENU 4.5
TBP 4.5
Methylphenidate 4.4
norleucine 4.4
GABA 4.3
Choline 4.3
Minocycline 4.2
DEP 4.2
GABA 4.2
SSM 4.2
Cer 4.1
Neuronal 4.1
Trehalose 4.1
norleucine 4.1
SPD 4.0
DPA 4.0
DPA 4.0
5-methylisoxazole 4.0
Baclofen 3.9
DPA 3.9
Heparan sulfate 3.9
Thiamine 3.9
DPA 3.8
CoQ 3.8
DPA 3.8
Ubiquitin 3.8
NMDA 3.7
DAB 3.7
DPA 3.7
AMPA 3.7
gamma-aminobutyric acid 3.6
ANA 3.6
ANA 3.6
Ins(1,4,5)P3 3.6
DAT 3.6
APV 3.6
DPA 3.6
5-HIAA 3.6
AICAR 3.6
DPA 3.6
DPA 3.6
DPA 3.6
DPA 3.6
more...