Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0153470 (Spleen)
 4,015 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thymus 345
lymphoid 325
Sep 265
fused 252
cytokine 202
lipopolysaccharide 193
IFN-gamma 190
interferon 167
IL-2 156
IL-4 138
CD4 136
IL-10 117
DBA 107
interleukin-2 106
Thy-1 106
CD8 104
LPS 100
IFN 98
interferon-gamma 84
SRBC 82
B10 72
lymphokine 68
Mol 65
IL-6 65
major histocompatibility complex 62
serum albumin 61
MHC 58
TNF 56
IgE 56
interleukin 2 56
erythroid 53
PHA 53
hemoglobin 52
IgA 47
IL-5 46
glycoprotein 46
IL-1 45
tumor necrosis factor 44
SP2 42
interleukin-4 40
PFC 37
NS-1 33
albumin 33
TNF-alpha 32
lectin 31
granulocyte 29
polypeptide 29
natural killer cell 28
Cytokine 28
collagen 26
IL-3 25
GM-CSF 25
insulin 25
SDS 24
gut 24
MHC class II 22
IL-17 22
TCR 21
MLR 21
CD45 20
inducible nitric oxide synthase 20
peroxidase 19
thyroglobulin 19
alkaline phosphatase 19
interleukin-6 19
erythropoietin 19
CD25 18
superoxide dismutase 17
T cell receptor 17
mouse) 17
myelin basic protein 17
CSF 17
macrophage colony-stimulating factor 16
CD86 15
MHC class I 15
ferritin 15
TGF-beta 15
interferon gamma 14
tumor necrosis factor alpha 14
catalase 14
PPD 14
surface antigen 14
IgG3 14
CD11b 14
HLA 14
granulocyte-macrophage 14
esterase 14
X-linked 14
IL-2 receptor 13
heavy chain 13
Gen 13
CD80 12
lysozyme 12
neuraminidase 12
interleukin-10 12
CD40 12
She 12
NK1 12
NS1 12
GSH 12
glucan 11
NOD 11
MLC 11
p53 11
casein 11
Fas 11
microsomal 11
IL-13 10
IL2 10
AMP 10
CD28 10
mast cell 10
PBS 9
granulocyte-macrophage colony-stimulating factor 9
glutathione peroxidase 9
chemokine 9
CD5 9
severe combined immunodeficiency 9
T-cell growth factor 9
APC 9
T cell growth factor 9
chorionic gonadotropin 9
CD11c 9
granulocyte colony-stimulating factor 9
LFA-1 9
membrane protein 9
serum protein 9
myelin oligodendrocyte glycoprotein 9
nitric oxide synthase 9
TH1 9
cage 9
IL-1 beta 8
caspase-3 8
cell surface antigen 8
RPMI 8
transferrin 8
NIP 8
growth hormone 8
HAT 8
perforin 8
lactate dehydrogenase 8
membrane-bound 8
colon carcinoma 8
IL-18 8
env 8
SOD 8
aspartate aminotransferase 8
Fc gamma 8
methemoglobin 8
fibrinogen 8
Bcl-2 8
PEG 8
LAK 7
IL-1 alpha 7
Fc receptor 7
collagenase 7
G10 7
acid phosphatase 7
lymphotoxin 7
type II collagen 7
more...
Disease
Spleen 4015
tumor 476
cancer 311
multiple myeloma 248
plaque 146
leukemia 115
DBA 107
tumor growth 93
lymphoma 86
depression 53
PHA 53
anemia 51
sarcoma 50
malaria 49
Mycobacterium 49
malnutrition 49
Thymus 47
Thymus 47
Thymus 47
virus infection 44
infectious diseases 42
fibrosarcoma 40
cold 40
graft-versus-host disease 39
diabetes 39
encephalomyelitis 37
systemic lupus erythematosus 36
Infection 36
immunodeficiency 34
carcinoma 34
adenocarcinoma 32
melanoma 30
thrombocytopenia 29
influenza 28
arthritis 28
tuberculosis 28
plasmacytoma 27
leishmaniasis 27
hepatocellular carcinoma 27
Brucella abortus 27
sepsis 27
Syndrome 26
portal hypertension 25
metastases 25
vaccinia 24
SDS 24
hepatitis 24
sepsis 24
autoimmune disease 23
cirrhosis 23
Mycoplasma 23
AIDS 22
pertussis 22
mastocytoma 22
lupus 20
Hodgkin's disease 19
Stomach 19
lupus 19
Stomach 19
Stomach 19
Stomach 19
Brown 19
Schistosoma mansoni 18
cytomegalovirus 18
SCID 17
Newcastle disease 17
lung carcinoma 17
herpes simplex 17
Marek's disease 17
immunotoxicity 16
schistosomiasis 16
Bordetella 16
HIV 15
tumorigenesis 15
cholera 15
EL4 14
stroke 14
rheumatoid arthritis 14
worms 14
gastric cancer 14
multiple sclerosis 13
mammary tumor 13
chronic myeloid leukemia 13
autoimmune thyroiditis 13
lymphadenopathy 13
myelofibrosis 13
lung cancer 12
Cryptococcus neoformans 12
GSH 12
Friend leukemia 12
thymoma 12
renal disease 12
lymphocytic choriomeningitis 11
erythroleukemia 11
Leukemia 11
uterus 11
Echinococcus 11
L. infantum 11
MLC 11
lung metastases 11
NOD 11
obesity 11
idiopathic thrombocytopenic purpura 11
hepatitis B 11
varices 10
lymphocytosis 10
B-cell lymphoma 10
Yersinia 10
myocarditis 10
esophageal varices 10
ischemia 9
acute myeloid leukemia 9
tetanus 9
kala-azar 9
hypersplenism 9
breast cancer 9
APC 9
hemosiderosis 9
proteinuria 9
lymphopenia 8
bacterial infection 8
epididymis 8
neuroblastoma 8
liver disease 8
asthma 8
wasting 8
hypertension 8
immunopathology 8
salmonellosis 8
coxsackievirus 8
chronic hepatitis 8
glomerulonephritis 8
chronic lymphocytic leukemia 7
Chagas 7
acute lymphoblastic leukemia 7
Colon 7
hairy cell leukemia 7
Colon 7
sickle cell disease 7
carcinogenesis 7
tumor progression 7
viremia 7
primary tumor 7
lymphosarcoma 7
diphtheria 7
myasthenia gravis 7
Blocking 7
Colon 7
TEM 7
SEM 7
suicide 6
myeloid leukemia 6
Pancreas 6
mole 6
CTX 6
mole 6
TAM 6
pneumonia 6
Epstein 6
Legionella 6
more...
Symptom
splenomegaly 111
diarrhea 22
abdominal pain 17
pain 17
hepatomegaly 14
fatigue 12
hepatosplenomegaly 9
anorexia 9
lethargy 8
weakness 8
anesthesia 7
asthenia 6
nausea 6
exhaustion 6
HSA 5
vomiting 5
functional recovery 4
pallor 4
cachexia 3
respiratory distress 3
chromosome marker 3
headache 3
acute stress 3
dyspnea 3
analgesia 3
abnormal breathing 2
acute abdomen 2
starvation 2
ataxia 2
agitation 2
tremor 2
bone pain 2
cyanosis 2
Ear swelling 2
Wind 2
incoordination 2
seizures 2
prostration 2
pelvic pain 1
chills 1
Ill 1
cancer pain 1
hypothermia 1
discomfort 1
insomnia 1
Crawling 1
abdominal discomfort 1
epigastric pain 1
hunger 1
eye discharge 1
nausea and vomiting 1
night sweats 1
spasm 1
apathy 1
numbness 1
loss of balance 1
Welt 1
Skin thickening 1
cerebellar ataxia 1
consciousness disturbance 1
cough 1
erythema 1
Decreased activity 1
decreased appetite 1
hyperoxia 1
syncope 1
low back pain 1
lassitude 1
acute abdominal pain 1
myalgia 1
dizziness 1
discomfort 1
tachypnea 1
hypoproteinemia 1
enuresis 1
Drug
IFN-gamma 186
IL-2 163
CSF 36
Meth 21
lysine 14
CTX 14
vitamin E 8
Indomethacin 7
Dermatol 6
CTX 6
CTX 6
Hypaque 5
Hypaque 5
BCG vaccine 5
Adriamycin 5
MRC 5
Portal 5
G-CSF 5
ascorbate 5
Ethanol 4
Nephron 4
IFN-beta 4
ABC 4
ROS 4
Histamine 3
Mutagen 3
Asthma 3
NAG 3
THF 3
Bifidobacterium 3
Glutathione 3
Gel 3
PTH 2
CaCl2 2
lactose 2
Spectrum 2
LCM 2
Thyroglobulin 2
Silica 2
G418 2
LCM 2
PCB 2
ZnO 2
Cimetidine 2
Asn 2
CaCl2 2
Spectrum 2
Pentostam 2
CaCl2 2
Cimetidine 2
p75 2
Glide 2
9-THC 2
Allergen 2
Nephron 2
Doxycycline 1
Orlistat 1
ALA 1
ACT 1
Luteinizing 1
RbCl 1
Oxaliplatin 1
Imatinib 1
AmBisome 1
Growth hormone 1
Glycyrrhiza 1
Bestatin 1
Casodex 1
Papain 1
Paraffin 1
ISP 1
Sodium valproate 1
AZT 1
Lomotil 1
Velban 1
HCH 1
Novantrone 1
ETS 1
nitroglycerin 1
MgSO4 1
ROC 1
Serum albumin 1
Camp 1
Pronase 1
TAK 1
Tuberculin 1
NBT 1
pyridoxal phosphate 1
Xanthan gum 1
Lipiodol 1
Ammonium chloride 1
Thymopentin 1
Rutin 1
Lead acetate 1
Digenea 1
Mitomycin-C 1
balanced salt solution 1
BLyS 1
Syrup 1
CDX 1
ampicillin 1
Fluorescein 1
KCL 1
Vitamin A 1
Dakar 1
Leaf 1
Arsenic trioxide 1
RAL 1
Everolimus 1
Vitamin K 1
Cardiovasc 1
Cetrorelix 1
DNase I 1
Caspofungin 1
Monensin 1
Tacrolimus 1
CET 1
MAP 1
FAD 1
AZT 1
Ouabain 1
Rituximab 1
Artesunate 1
Span 20 1
Podophyllum 1
RbCl 1
AKM 1
IL-11 1
CAM 1
Glycerol 1
ADR 1
Desferal 1
Podophyllotoxin 1
Clonidine 1
Simvastatin 1
Rhubarb 1
Norplant 1
Fraction 1
Gelatin 1
Desferal 1
Buspar 1
OMP 1
MTC 1
CDX 1
Cerezyme 1
Glucantime 1
Span 60 1
Coconut oil 1
EPA 1
HCG 1
Horizon 1
Heme 1
AraC 1
IPD 1
Ringer's solution 1
Ceredase 1
Diurnal 1
Aloe 1
Growth hormone 1
PDL 1
more...
Enzyme
peroxidase 29
superoxide dismutase 25
trypsin 20
alkaline phosphatase 19
focal adhesion kinase 16
catalase 15
neuraminidase 13
lysozyme 13
reverse transcriptase 13
alanine aminotransferase 13
ERK 12
aspartate aminotransferase 11
Thy1 9
glutathione peroxidase 9
APC 9
lactate dehydrogenase 9
beta-galactosidase 9
ATPase 7
collagenase 7
acid phosphatase 7
RNase 7
RNase 7
protein kinase 6
protein kinase C 6
NO synthase 6
papain 6
adenylate cyclase 6
kallikrein 6
chymotrypsin 6
thrombin 5
ceruloplasmin 5
adenosine deaminase 5
DNase 5
caspase-3 5
adenosine deaminase 5
ribonuclease 4
heme oxygenase 4
ribonuclease 4
mitogen-activated protein kinase 4
prostaglandin synthetase 4
cholinesterase 4
bromelain 4
plasmin 3
purine nucleoside phosphorylase 3
beta-glucuronidase 3
PARP 3
acetylcholinesterase 3
AST 3
proteinase K 3
phospholipase C 3
hypoxanthine-guanine phosphoribosyltransferase 2
glyceraldehyde-3-phosphate dehydrogenase 2
RNA polymerase 2
phosphoenolpyruvate carboxykinase 2
cruzipain 2
MIP 2
phosphoenolpyruvate carboxykinase 2
TdT 2
renin 2
NADPH oxidase 2
hexosaminidase 2
transglutaminase 2
arginase 2
dopamine beta-hydroxylase 2
tissue kallikrein 2
elastase 2
neutrophil elastase 2
deoxyribonuclease 2
5'-nucleotidase 2
glyceraldehyde-3-phosphate dehydrogenase 2
glucocerebrosidase 2
TSA 2
phosphoenolpyruvate carboxykinase 2
glucose oxidase 2
cytochrome oxidase 2
NADPH oxidase 2
beta-lactamase 2
beta-glucosidase 2
beta-glucosidase 2
deoxyribonuclease 2
pepsin 2
NOS 2
luciferase 2
MAT 2
phosphodiesterase 2
glutathione S-transferase 2
transcriptase 2
thymidine kinase 2
tyrosine hydroxylase 2
glyceraldehyde-3-phosphate dehydrogenase 2
TDH 2
phospholipase A2 2
glutathione reductase 2
chloramphenicol acetyltransferase 2
PDE 2
cathepsin K 2
MAT 2
cGMP phosphodiesterase 1
p80 1
glyceraldehyde-3-phosphate dehydrogenase 1
ricin 1
tyrosinase 1
sialidase 1
histidine decarboxylase 1
nucleotidase 1
matrix metalloproteinase 9 1
xanthine oxidase 1
leishmanolysin 1
deoxycytidine kinase 1
ADP-ribosyltransferase 1
lysin 1
ribonucleotide reductase 1
retinal oxidase 1
firefly luciferase 1
ribonucleotide reductase 1
estrogen sulfotransferase 1
thyroid peroxidase 1
MSAS 1
HSD 1
3-hydroxy-3-methylglutaryl-CoA reductase 1
chitinase 1
sorbitol dehydrogenase 1
sucrase 1
IKK 1
GSK 1
aspartate transcarbamylase 1
ornithine decarboxylase 1
nucleotide pyrophosphatase 1
TSR 1
AMP-activated protein kinase 1
urease 1
monoamine oxidase 1
aldehyde reductase 1
gamma-glutamyl transpeptidase 1
dipeptidyl peptidase IV 1
DNA methyltransferase 1
DNA polymerase 1
CCS 1
phosphatidylinositol phospholipase C 1
enolase 1
cathepsin G 1
ADP-ribosyltransferase 1
deoxyadenosine kinase 1
complex I 1
factor D 1
ferrochelatase 1
proton-translocating ATPase 1
ACE 1
proteasome 1
alpha-glucosidase 1
phosphoglycerate kinase 1
thromboplastin 1
galactose oxidase 1
creatine kinase 1
MDR 1
ALA synthase 1
asparaginase 1
alpha-mannosidase 1
tissue plasminogen activator 1
glucose-6-phosphatase 1
more...
Compound
Dec 286
DNA 247
Clin 160
DBA 107
DBA 107
DBA 107
water 89
iron 76
sodium 58
TNF 56
nitric oxide 47
glucose 40
DNP 38
BCG 38
calcium 36
tyrosine 36
sulfate 35
GM1 35
acetate 34
TCM 31
TCM 31
oxygen 29
PEG 27
SDS 25
ethanol 23
phosphate 23
arginine 23
copper 20
lysine 20
Tyrosine 19
zinc 19
nitrogen 17
PPD 17
2-mercaptoethanol 15
urea 15
PPD 14
CTX 14
chromium 14
GSH 14
cAMP 14
GSH 14
PEG 13
PGE2 12
methionine 12
ammonium 12
AMP 12
leucine 12
cadmium 12
salt 11
DEAE 11
galactose 11
thioglycollate 10
nitrate 10
alanine 9
MDA 9
Optimal 9
cysteine 9
EDTA 9
Cyclosporine 8
EDTA 8
glutamic acid 8
aluminum 8
aniline 8
acetic acid 7
Hemoglobin 7
Phe 7
formaldehyde 7
His 7
benzene 7
bromide 7
creatinine 7
cGMP 7
silver 6
hydroxide 6
selenium 6
formaldehyde 6
ATP 6
MCA 6
MMC 6
BCNU 6
AFC 6
phenol 6
ACI 6
xylose 6
pyrene 6
Indomethacin 6
Triton X-100 6
Testosterone 6
Testosterone 6
glutamate 6
potassium 5
Thymidine 5
PMA 5
DDD 5
MCA 5
mercury 5
PMA 5
threonine 5
A 3 5
serine 5
PNA 5
NH2 5
methanol 5
Interleukin-2 5
GalNAc 5
Hypaque 5
iodine 5
ADP 5
cobalt 5
uridine 5
Poly I 5
Adriamycin 5
acrylamide 4
Salt 4
BUdR 4
5-HT 4
ASA 4
palmitic acid 4
CO2 4
Asp 4
Gly 4
acetone 4
vitamin D 4
MTT 4
HgCl2 4
ADP 4
MCH 4
Adrenal 4
phosphorus 4
CTP 4
ABL 4
ADP 4
ACTH 4
TEM 4
A 1 4
dUTP 4
NPP 3
aflatoxin B1 3
Cholesterol 3
manganese 3
THF 3
hydrogen 3
UTP 3
COS 3
APS 3
Mg2+ 3
PAP 3
Cortisol 3
BLM 3
glycerol 3
Estrogen 3
superoxide radical 3
chloroform 3
barium 3
Corticosterone 3
BCR 3
PGE 3
NO3 3
CdCl2 3
SPF 3
more...