Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0153470 (
Spleen
)
4,015
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In this communication, we have demonstrated that hydrolysis of the nucleotide sugar can cause errors in the detection of an ectoglycosyltransferase.
Spleen
cell suspensions can incorporate radioactivity when incubated with labeled
UDP-galactose
, but all the activity is due to decomposition of the nucleotide sugar and uptake of the free sugar. The fibroblast cell lines can incroporate carbohydrate directly from
UDP-galactose
. Several criteria are presented with can be used to demonstrate that a nucleotide sugar is the direct carbohydrate donor.
...
PMID:Ectogalactosyltransferase studies in fibroblasts and concanavalin A-stimulated lymphocytes. 103 Jul 11