Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0153429 (Meckel's diverticulum)
 1,196 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Effects of the ionophoric anticoccidial agent monensin on glucose and amino acid absorption were investigated in young broiler chickens. Chicks housed in cages with wire floors were fed a practical diet containing 0 or 121 ppm monensin for 2 to 3 weeks prior to measurement of nutrient absorption. Chicks were anesthetized with halothane, and the intestine was accessed through an incision in the abdominal wall. A 10-cm segment of the intestine immediately anterior to Meckel's diverticulum was rinsed free of digesta and used for measurement of absorption in situ. One milliliter of saline solution containing 2 mM of glucose or a mixture of amino acids was injected into the lumen of the ligated segment, and recovery of glucose and amino acids in the lumen was determined after 4- and 5-min intervals, respectively. In one glucose study, the solution contained 0, 1, 10, or 80 micrograms/ml of monensin. In one amino acid study, the solution contained 0, 5, or 80 micrograms/ml of monensin; in subsequent studies, monensin was not included in the solution. Results show that neither dietary monensin nor monensin in the saline solution affected glucose absorption. Dietary monensin tended to depress lysine absorption but increased the absorption of tryptophan and arginine, the latter amino acid being markedly affected by monensin. Dietary monensin alone had no effect on absorption of cystine, isoleucine, methionine, or threonine. Inclusion of monensin in the saline solution depressed methionine absorption but only when birds also had been fed the diet containing monensin. Monensin in the saline solution depressed isoleucine absorption irrespective of dietary treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Intestinal absorption of glucose and amino acids in chickens administered monensin. 357 18

The objective of this study was to determine the effect of the duration of prefeeding on prececal amino acid (AA) digestibility of wheat distillers dried grains with solubles (DDGS) in broilers. The experimental diets with DDGS at levels of 0, 10, and 20% were offered ad libitum for 7, 5, and 3 d, starting on 14, 16, and 18 d of age. Titanium dioxide was used as an indigestible marker. Six pens of 10 birds were allocated to each treatment. Digesta was sampled on a pen basis from the distal two-thirds of the intestine section between Meckel's diverticulum and 2 cm anterior to the ileo-ceca-colonic junction. Ingested and digested amounts of AA were determined for each pen. Digestibility of AA in the diets was not significantly affected by the duration of prefeeding but was significantly reduced by inclusion of DDGS. Digestibility of AA in DDGS was determined by using a linear regression approach. The digestibility of AA in DDGS ranged from 76% (Arg, 5 d of feeding) to 33% (Asp, 3 d of feeding). There was no significant effect of prefeeding time on AA digestibility of DDGS. Lysine digestibility of DDGS was 72%. The mean digestibility of the AA Arg, Cys, Ile, Leu, Lys, Met, Phe, Thr, and Val of DDGS across the 3 prefeeding times was 66%. This study gave evidence that 3 d of prefeeding a diet is sufficient in studying prececal AA digestibility in broilers when low-digestible feeds are used.
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PMID:Effect of the duration of prefeeding on amino acid digestibility of wheat distillers dried grains with solubles in broiler chicken. 2030 99