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Target Concepts:
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Query: UMLS:C0153429 (
Meckel's diverticulum
)
1,196
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The small intestine is a frequent site for metastases of cutaneous or ocular melanoma. When the latter are absent, the diagnosis of primary intestinal
melanoma
can be proposed. Primary
malignant melanoma
of the small intestine arises from melanoblastic cells of the neural crests, which migrate to the distal ileum through the omphalomesenteric canal. Incomplete regression of the later leads to persistence of
Meckel's diverticulum
. We report herein a case of
malignant melanoma
of the small intestine without evidence of a cutaneous and/or ocular origin. Based on its location in the distal ileum, we propose that this tumor be classified as a primary
malignant melanoma
of the small intestine.
...
PMID:[Primary malignant melanoma of the small intestine]. 139 58
Meckel's diverticulum
is a vestigial remnant of the omphalomesenteric duct, which is rarely affected by neoplasia. The authors report the first case of
malignant melanoma
in
Meckel's diverticulum
in a middle-aged man without skin or ocular lesions. Five other Meckel's diverticuli were evaluated histologically and by immunoperoxidase technics for neural crest elements, which could have given rise to this lesion.
...
PMID:Malignant melanoma in Meckel's diverticulum. 373 73
