Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0153429 (Meckel's diverticulum)
 1,196 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Neoplasia is the least common complication of Meckel's diverticulum. A case of partial obstruction of the small intestine due to adenocarcinoma arising in a Meckel's diverticulum is presented. The noteworthy feature of this case is the presence of neoplastic Paneth cells in the tumor.
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PMID:Neoplastic Paneth cells. Occurrence in an Adenocarcinoma of a Meckel's diverticulum. 5 Jul 29

Acute intestinal obstruction in a women, aged 56, was caused by a highly malignant adenocarcinoma arising in a Meckel's diverticulum. Despite radical surgery, the tumour recurred after four months, and the patient died nine months after her first operation. This confirms the general bad prognosis associated with carcimomas of Meckel's diverticulum.
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PMID:Carcinoma of Meckel's diverticulum. 49 65

A 54-yr-old man who complained of abdominal pain was found to have an adenocarcinoma arising in Meckel's diverticulum, as preoperatively diagnosed with 99mTc-pertechnetate scintigraphy. Angiography of the superior mesenteric artery revealed multiple branched arteries and tumor stain, but the vitelline artery was not clearly identified. Surgery revealed that the tumor had invaded the urinary bladder and the ileum, including the diverticulum, and the bladder had to be partially resected. Histopathological examination of the lesion revealed a diverticulum containing normal small bowel mucosa, ectopic normal gastric tissue, and adenocarcinoma. In a review of 30 cases of adenocarcinoma in Meckel's diverticulum in the English and Japanese literature, our case was the first to be diagnosed preoperatively.
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PMID:Adenocarcinoma in Meckel's diverticulum: report of a case and review of 30 cases in the English and Japanese literature. 161 50

Stapler resection of Meckel's diverticulum was performed on 16 patients with known or presumed gynecologic malignancy at the time of extended abdominal surgery. All diverticulectomies were done quickly and without morbidity. Heterotropic gastric epithelium was found in one diverticulum, and one other patient with stage III ovarian adenocarcinoma had metastases to the serosa of her Meckel's diverticulum.
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PMID:Stapler resection of Meckel's diverticulum during gynecologic cancer surgery. 238 36

A case of adenocarcinoma of Meckel's diverticulum is reported. Small bowel neoplasias are the least frequent in the gastrointestinal tract and localization to the diverticulum is extremely rare. Among histological types, adenocarcinoma accounts for the minority of cases. Early diagnosis is difficult because of lack of specificity of signs and symptoms, except in advanced stages. Small bowel resection with lymphadenectomy is the recommended therapeutic approach. Although, in reported case it could not be performed, because of the diffuse intraabdominal metastasis at diagnosis. This and similar cases would open the discussion about a possible indication for prophylactic resection of Meckel's diverticulum. No definitive conclusion can be drawn at present since no follow-up study is available on the natural history of diverticula which have been observed during abdominal surgery and have not been resected.
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PMID:[Adenocarcinoma of Meckel's diverticulum]. 262 96

A case of adenocarcinoma arising in Meckel's diverticulum in a 55 year old man is reported, and a brief review of the literature is presented. The patient developed low abdominal pain and showed elevation of serum carcinoembryonic antigen (CEA) level. The tumour was located in the apical portion of the diverticulum and extended into the mesenterium. Histologically, the tumour was a well-differentiated adenocarcinoma arising in the Meckel's diverticulum. Immunohistochemical study showed that malignant cells were positive for CEA. The noteworthy feature of this case is the pre-operative elevation of serum CEA level and the immunohistochemical demonstration of CEA in the cancer cells.
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PMID:Adenocarcinoma in Meckel's diverticulum: case report and literature review. 268 22

A 23-year-old male presented with occult gastrointestinal bleeding and iron deficiency anemia. A Tc-99m pertechnetate abdominal scan was positive and surgery revealed an adenocarcinoma of the cecum. No Meckel's diverticulum was identified. This is the first reported association of an abnormal Tc-99m pertechnetate scan in adenocarcinoma. Carcinoma of the right colon should be considered in any patient with a positive pertechnetate scan for Meckel's diverticulum and suggestive clinical features.
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PMID:Detection of cecal adenocarcinoma by Tc-99m pertechnetate scintigram. 609 72

The clinicopathologic features of a case of adenocarcinoma arising in Meckel's diverticulum are described and compared with the 21 cases reported in the literature. The prognosis is generally poor. However, the patient in the present case was alive and well 1.5 years after diagnosis, despite the fact that the lesion had perforated at initial presentation.
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PMID:Adenocarcinoma of Meckel's diverticulum. 684 30

11 cases of intussusception in adults, including 9 treated by operation, are discussed. The cause of the intussusception was a malignant lesion in 7 and a benign lesion in 2 cases. In 2 patients, reposition was achieved with the aid of a barium enema. Aetiology and clinical and radiological features are discussed. In view of the high incidence of pre-existent lesions and the risk of perforation at reposition with the aid of a barium enema, surgical therapy is indicated. The pre-existent lesions found at operation and pathological anatomical examination were: malignant lymphoma (4 cases), caecal adenocarcinoma (2 cases), leiomyofibroma of the ileum (1 case), caecal endometriosis (1 case), carcinoid appendix (1 case) and Meckel's diverticulum (2 cases).
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PMID:Intussusception in adults. 698 49

A woman aged 49 complained of longstanding umbilical discharge. In the floor of the navel a granulomatoid lesion was observed, which histopathologically proved to be a well-differentiated adenocarcinoma. This was thought to be a primary tumour as extensive investigation revealed no other primary tumour. The umbilical area was excised. Colonic malrotation was seen as well as a Meckel's diverticulum. The patient recovered completely.
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PMID:[Primary adenocarcinoma of the navel after a seemingly harmless discharge of many years' duration]. 839 13


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