Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152169 (renal colic)
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Human Gene/Protein
PRPS1 9.6
lok 9.4
Hil 9.1
Mevalonate kinase 8.9
CDC73 8.5
HM3 8.3
homogentisate 1,2-dioxygenase 8.0
Rho-associated protein kinase 1 7.9
parafibromin 7.9
XDH 7.8
NOVA 7.6
P2X2 6.9
P2X3 6.9
von Hippel-Lindau tumor suppressor 6.6
CCK-B 6.6
CCK-4 6.6
pancreatic secretory trypsin inhibitor 6.5
sulfite oxidase 6.5
xanthine oxidoreductase 6.3
MEN1 6.1
CCK-A 5.8
MAG 5.7
aldehyde oxidase 5.6
FDP 5.5
EFS 5.5
PGL 5.4
ECL 5.4
MPL 5.4
panhypopituitarism 5.2
PID 5.2
neutrophil gelatinase-associated lipocalin 5.1
hypoxanthine-guanine phosphoribosyltransferase 5.0
P15 5.0
trypsinogen 5.0
OFQ 5.0
STING 4.9
DLD 4.9
Wilson disease 4.9
UTI 4.8
CD138 4.7
SOX9 4.6
MIM 4.4
parathormone 4.4
T11 4.3
non-functional 4.3
MDP 4.3
X-linked recessive 4.3
parathyroid hormone 4.2
STS 4.1
Factor VIII 4.1
T10 4.0
serine protease inhibitor 4.0
HCG 3.9
hemophilia A 3.8
CFTR 3.8
reserved 3.8
CAT 3.7
FVIII 3.7
calcium channel 3.7
She 3.6
Smad3 3.4
neuron-specific enolase 3.3
protease inhibitor 3.3
Albumin 3.3
ceruloplasmin 3.2
GFR 3.2
NLRP3 3.2
chronic renal failure 3.1
collecting duct 2.9
CHOP 2.9
PSA 2.8
ankylosing spondylitis 2.8
lacrimal 2.7
tissue plasminogen activator 2.6
Mil 2.6
muscarinic receptor 2.6
PTH 2.5
arginine vasopressin 2.5
Boc 2.5
carbonic anhydrase 2.4
more...
Disease
Acute renal disease 14.3
Early cirrhosis 14.3
Ovarian vein syndrome 12.9
fourth disease 12.7
Ureteritis cystica 12.6
Hereditary chronic pancreatitis 12.1
Splenic lymphoma 11.9
Medullary nephrocalcinosis 11.8
ureterolithiasis 11.6
Aortoduodenal fistula 11.6
Xanthinuria 11.5
Retroperitoneal sarcoma 11.5
ureterectasis 11.0
Cystitis glandularis 11.0
Idiopathic hypercalciuria 10.9
Urogenital tuberculosis 10.8
Renal infarction 10.7
metastatic hypernephroma 10.6
periappendicitis 10.4
gouty nephropathy 10.2
Ruptured abdominal aortic aneurysm 10.1
sponge kidney 10.1
Obstructive nephropathy 10.1
APRT deficiency 9.9
urolithiasis 9.8
nephrolithiasis 9.7
ovarian endometrioid adenocarcinoma 9.6
podagra 9.4
Parathyroid adenoma 9.4
Splenic artery aneurysm 9.3
Fungal endocarditis 9.2
paraphimosis 9.2
urinary tract obstruction 9.1
staghorn calculus 9.0
Mesenteric panniculitis 8.8
renal papillary necrosis 8.7
hydroureteronephrosis 8.7
ureter 8.7
tophi 8.7
nephroptosis 8.7
biliary colic 8.6
renal glycosuria 8.6
Munchausen syndrome 8.6
hydronephrosis 8.6
pyonephrosis 8.6
chronic urinary tract infection 8.6
Ureteral obstruction 8.6
Abdominal compartment syndrome 8.6
hemoglobinemia 8.4
HRPT2 8.4
uricosuria 8.4
cystinuria 8.3
Acute generalized exanthematous pustulosis 8.3
uropathy 8.3
Asymptomatic bacteriuria 8.2
hyperoxaluria 8.2
radiculitis 8.2
pyelonephritis 8.1
pyelitis 8.1
ureteritis 8.0
hypercalciuria 8.0
Boerhaave's syndrome 8.0
ureterocele 7.9
mesenteric thrombosis 7.8
Xanthogranulomatous pyelonephritis 7.8
hypoactive sexual desire disorder 7.7
mesenteric lymphadenitis 7.6
anuria 7.6
pyuria 7.6
Diaz 7.6
Opiates 7.5
adenomatoid tumor 7.5
adnexitis 7.4
sickle cell crisis 7.4
diverticulitis 7.4
nephrocalcinosis 7.3
hypoaldosteronism 7.2
metastatic bladder cancer 7.1
appendicitis 7.1
hypermagnesemia 6.9
more...
Symptom
renal colic 15.3
Ureteric colic 13.3
Acute pelvic pain 11.0
urological problem 10.4
flank pain 10.4
Labor pain 10.3
loin pain 9.7
left lower quadrant pain 9.4
renal pain 9.2
colic 9.0
chyluria 8.7
prostatism 8.1
frequent urination 7.8
Lower urinary tract symptoms 7.7
dysuria 7.7
acute abdominal pain 7.3
periorbital edema 7.3
acute low back pain 7.2
right lower quadrant pain 7.0
testicular pain 6.8
oliguria 6.7
groin pain 6.7
acute pain 6.6
acute abdomen 6.5
ketonuria 6.2
urinary frequency 6.1
dental pain 6.0
polyuria 6.0
limb pain 5.9
right upper quadrant pain 5.8
analgesia 5.7
sciatica 5.7
abdominal pain 5.4
back pain 5.3
pelvic pain 5.3
night sweats 5.0
spasm 5.0
pain 4.9
Sedation 4.9
vomiting 4.8
nausea 4.7
cancer pain 4.7
bloating 4.6
epigastric pain 4.5
abdominal discomfort 4.5
stridor 4.1
nausea and vomiting 4.0
low back pain 4.0
pallor 4.0
sore throat 3.8
chest pain 3.8
bone pain 3.7
dizziness 3.6
ophthalmoplegia 3.6
arthralgia 3.4
memory loss 3.4
sleepiness 3.2
chills 3.2
hepatosplenomegaly 3.2
discomfort 3.1
discomfort 3.0
splenomegaly 3.0
hepatomegaly 2.8
cough 2.7
myalgia 2.6
anorexia 2.5
headache 2.5
anesthesia 2.4
fatigue 2.2
syncope 2.1
constipation 1.9
thinning 1.8
agitation 1.7
weakness 1.6
stigma 1.6
functional recovery 1.5
dyspnea 1.5
diarrhea 1.4
ataxia 1.3
respiratory distress 1.0
more...
Drug
Nefopam hydrochloride 11.4
Zomepirac sodium 11.3
Feldene 10.1
Ketorolac tromethamine 10.0
Indoprofen 9.9
Ketorolac 9.9
Oxycon 9.7
Parecoxib 9.5
Profenid 9.3
Ceruletide 9.1
Butorphanol 8.8
Crixivan 8.4
Dipyrone 8.4
Indinavir 8.3
Febuxostat 8.1
Cinacalcet 7.6
Diclofenac sodium 7.5
Mesalazine 7.4
Papaverine 7.4
Voltaren 7.3
Mezlocillin 7.2
Vena 7.0
Vena 7.0
Salicylate 6.1
Gastro 5.4
Prednisone 5.3
Diphenhydramine 5.2
Scopolamine 4.9
TAC 4.6
Theophylline 4.3
HCG 3.9
Albumin 3.0
Nephron 2.7
Indomethacin 2.6
PTH 2.5
lysine 2.2
Nephron 2.1
Ethanol 2.0
Dial 1.4
caffeine 0.9
Leaf 0.9
ascorbate 0.8
Dermatol -2.7
Enzyme
homogentisate 1,2-dioxygenase 7.7
adenine phosphoribosyltransferase 7.4
PRPP synthetase 7.3
PNL 6.8
prostaglandin synthetase 6.7
sulfite oxidase 6.5
sulfite oxidase 6.4
aldehyde oxidase 5.7
xanthine dehydrogenase 5.0
PAL 4.6
hypoxanthine-guanine phosphoribosyltransferase 4.0
ceruloplasmin 4.0
MDP 3.9
xanthine oxidase 3.2
aldehyde dehydrogenase 2.9
prostate-specific antigen 2.5
carbonic anhydrase 2.4
ACE 2.1
transcriptase 2.1
tissue plasminogen activator 1.8
calcineurin 1.2
catalase 1.1
phosphodiesterase 1.1
aspartate aminotransferase 0.9
alkaline phosphatase 0.7
reverse transcriptase 0.3
RNA polymerase 0.2
peroxidase -0.7
Compound
Indinavir sulfate 11.9
Benzbromarone 10.1
Tamsulosin 9.9
Ketorolac 9.8
Phloroglucinol 9.1
Phloroglucinol 9.0
Tolterodine 8.9
Butorphanol 8.9
EDAP 8.8
Indinavir 8.3
Phenacetin 8.3
MK-329 7.6
Alfentanil 7.4
Papaverine 7.4
Ketoprofen 7.3
Rosmarinic acid 6.9
Rosmarinic acid 6.9
Meperidine 6.9
Diclofenac 6.8
Xanthine 6.8
Prone 6.7
Keloid 6.6
Cystine 6.5
Acetazolamide 6.5
Aminophylline 6.2
Probenecid 6.0
Albendazole 5.9
Cystine 5.9
oxalate 5.8
Uric acid 5.8
FDP 5.3
PID 5.2
PID 5.2
Morphine 4.9
APAP 4.9
Theophylline 4.8
HPP 4.8
Nifedipine 4.7
nicotinic acid 4.7
nicotinic acid 4.7
nicotinic acid 4.6
Prednisone 4.6
Ibuprofen 4.5
T11 4.5
Prostaglandin 4.4
Prostaglandin 4.4
Salix 4.3
Piper 4.3
TCM 4.2
TCM 4.2
prostaglandin F2alpha 4.2
nicotinic acid 4.2
DHA 4.2
T10 4.0
DHA 4.0
Parenteral 4.0
SEE 4.0
creatinine 3.9
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
oxalic acid 3.8
CIT 3.8
CAT 3.7
CAT 3.7
CAT 3.6
DHA 3.6
oxalic acid 3.5
more...