Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0152169 (renal colic)
 811 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This study confirms that medullary sponge kidney (MSK) has a good prognosis, but there is a considerable morbidity in patients with renal calcification; they suffer renal colic, ureteric obstruction, and frequently need operation. There is a high incidence of urinary infection in women. On follow-up, glomerular function is well maintained, although careful testing shows a mild depression of glomerular filtration rate in at least 40%. Proximal tubular function is normal, but abnormalities of distal tubular function are often seen: acidification defects occur in 24% and are associated with nephrocalcinosis, poor urine concentrating ability, and diminished glomerular function. Urine concentration defects occur in 73% and are probably secondary to nephrocalcinosis. Hypercalciuria was present in 19% and was not related to other defects.
Proc Eur Dial Transplant Assoc 1977
PMID:Medullary sponge kidney: abnormalities of renal tubular and glomerular function, and their relationship to clinical features. 60 Sep 68

Thirty-four patients with analgesic nephropathy (AN) were investigated by realtime ultrasonography. In 11 of 14 dialysis patients and in 16 of 20 patients with renal insufficiency calcified renal papillae were documented surrounding the internal echo in a typical garland pattern. Incomplete garland pattern of papillary calcifications or development of hydronephrosis occurred in patients with a history of renal colic due to detachment of necrotic papillae. Moreover, AN was assumed in 10 patients with renal insufficiency of unknown origin after detection of typical ultrasonic signs of AN and confirmed by a hitherto unknown history of analgesic abuse.
Proc Eur Dial Transplant Assoc 1983
PMID:Ultrasonic findings in analgesic nephropathy. 665 87