Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152169 (renal colic)
 811 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Forty cases of primary hyperparathyroidism presenting over a 15 year period, have been reviewed. The disease was equally prevalent in both sexes with highest incidence in the sixth decade. Most patients presented with renal colic or calculi (73 percent) and skeletal disease was found in only 13 percent. A single parathyroid adenoma was found in 32 cases and hyperplasia was diagnosed in only two cases. Follow-up questionnaires were sent to 32 patients, and in 27 of these a full clinical and laboratory assessment was undertaken. Of 26 patients with renal colic preoperatively only six continued to experience colic one year after parathyroid surgery. Thirty percent of all patients were hypertensive preoperatively, and in only two patients did blood pressure normalise after surgery. Fourteen of 27 patients followed-up were found to be hypertensive. A highly significant fall was noted in serum calcium, chloride, alkaline phosphatase and urine calcium excretion postoperatively. Recurrence of the disease was low and less than 8 percent in this series. The low incidence (1 per 10 000 population per year) suggests that primary hyperparathyroidism is under diagnosed in the Christchurch community.
 ...
PMID:Primary hyperparathyroidism in a New Zealand community: a review of 40 cases. 29 Aug 84

There were 204 patients in one specific district with renal colic who were studied to determine the relationship of the condition to climatic conditions. It was found that stones were prone to cause colic on warm days when air pressure was falling.
 ...
PMID:Weather and the incidence of urinary stone colic. 43 Jun 25

Data from the Hospital In-patient Enquiry were used to define the regional patterns of hospital discharge rates for upper urinary tract stones and renal colic in England and Wales. By combining the rates for stones and colic, and by distinguishing emergency from planned admissions, the biases produced by repeated admissions of the same patient and by regional variations in diagnosis and coding may be reduced. There are regional variations in incidence of upper urinary tract stones: Wales and the southern regions of England have a generally higher incidence than northern regions. These variations may be related to regional differences in diet or occupation; or they may partly depend on associations between stone incidence and atmospheric temperature, exposure to ultraviolet irradiation, and hardness of drinking water.
 ...
PMID:Regional variations in the incidence of upper urinary tract stones in England and Wales. 62 Feb 1

Stone mass is a fundamental parameter that determines the approach to reno-ureteral lithiasis. Reference to stone size based on a single diameter gives us an imprecise idea about stone volume. For this reason, we recommend using the term "stone surface" to express stone mass. Stone surface is obtained by multiplying the longitudinal by the transversal diameter expressed in millimeters, using the plain film for radiopaque and the urogram for radiolucent calculi. Stone surface is a parameter which can be determined easily and is a more reliable way to determine stone volume. In 1,500 renal units with reno-ureteral calculi treated by ESWL and percutaneous techniques, we corroborated that the surface of calculus is directly associated with the number of shock waves required for fragmentation. Thus, as stone surface increases, more shock waves will be required to achieve fragmentation. The surface area of the calculus correlates very significatively with urinary tract obstruction post-ESWL. As the surface of the fragmented stone increases, there exists a higher incidence of obstruction. Obstruction is more severe and more ancillary maneuvers to remove obstruction are warranted. The incidence of renal colic post-ESWL is significantly influenced by the surface area of the calculus. There is a higher incidence of reno-ureteral colic following fragmentation of large stones. Furthermore, stone surface significantly determines the rate at which fragments are passed, and the persistence of stone sand at 3 months. Thus, as stone surface increases, there will be more fragments that can and cannot be spontaneously passed following treatment with ESWL. Finally, it must be emphasized that stone surface is a fundamental parameter that determines the combination of ancillary techniques prior to ESWL and significantly influences the efficacy of the approach in the treatment of reno-ureteral calculi.
 ...
PMID:[Influence of the lithiasic surface on the strategy: complications and results in the treatment of kidney calculi]. 269 47

We report a case of spontaneous rupture of the ureter from an impacted calculus, paradigm of diagnostic and therapeutic difficulties of these uncommon pathologic conditions. Spontaneous rupture of the ureter from an impacted calculus should be considered in cases of persistent renal colic and atypical presentation. Diagnosis is based on urographic evidence of urinary extravasation. This should be differentiated from nephric colic from urinary extravasation arising from the renal fornices which is relatively common in nephric colic. Treatment must always include drainage of the urinoma, ureteroraphy, and urinary diversion. However, a controversy exists on the advantages and disadvantages of nephrostomy versus ureteral splinting.
 ...
PMID:[Spontaneous rupture of the ureter caused by an impacted stone]. 281 94

The management of the patient presenting to the Emergency Department with nephrolithiasis or renal colic should include evaluation of the patient for concurrent diseases, risk factors for stone formation, and possible etiologies for stones. Suspicion of ureterolithiasis is based on a cogent history and physical examination and reinforced by a finding of hematuria. Diagnosis should be based upon a promptly performed intravenous pyelogram, unless the patient is truly allergic to contrast media or has substantial risk of a contrast-induced renal failure. A solitary flat plate of the abdomen adds no useful information and is an unnecessary expense to the patient. Essential laboratory data include a urinalysis, CBC, and electrolyte, BUN, creatinine, and serum calcium levels. A urine culture should be obtained in all patients because urinalysis alone may not be sufficient to exlude a urinary tract infection. Initial treatment of the patient with an uncomplicated renal colic should include hydration, relief of pain, and reassurance. Evaluation by a consultant may be done as an outpatient on a nonemergent basis. If the colic has not resolved after 72 hours, hospitalization generally is recommended. If the patient has vomiting, dehydration, a complete obstruction, or a solitary kidney, hospitalization in indicated and urgent consultation recommended. If the patient has fever or other signs of infection, emergent consultation and immediate hospitalization are essential. Retained obstructing stones are generally managed by urologic consultants. It is in the care of the patient with the retained stone that greatest advances have been made in the past 10 years. Patients should be counseled that the retained stone no longer calls for extended hospitalization and convalescence.
 ...
PMID:Nephrolithiasis. 329 30

In view of the part played by renal prostaglandins in the mechanisms responsible for pain in renal colic, it was worth trying to find out whether nonsteroidal anti-inflammatory agents, which inhibit prostaglandin synthesis, have an analgesic effect of their own. In a double-blind trial the effects of ketoprofen 100 mg administered intravenously alone or associated with noramidopyrine were investigated in 62 patients divided at random into two equal groups. A rapid analgesic effect was observed with no significant difference between the groups. No severe side-effects were recorded. The double-blind method made it possible to confirm that ketoprofen administered alone relieved pain in 97% of the patients (with complete sedation in 45%) and acted within 5 minutes. Owing to their effectiveness and safety nonsteroidal anti-inflammatory drugs (especially ketoprofen) may be proposed as an alternative to conventional treatments of renal colic. But because of their activity they should not be prescribed until a firm diagnosis has been made. The cause of the colic should also be rapidly determined in order to treat it as well as the pain it produces.
 ...
PMID:[Treatment of renal colic with intravenous ketoprofen]. 623 15

Acute radiorenography was compared to emergency excretory urography to evaluate its diagnostic accuracy in 22 patients with clinical signs of renal colic, including erythrocytes in the urinalysis. All 16 patients with delayed excretion and/or dilated renal pelves on excretory urography had delayed excretion of radioactivity on renography. Furthermore, 6 patients with reduced renal function judged by renography had marked or slight delay in excretion on excretory urography. Small stones not causing stasis were found on excretory urography in 2 patients with normal renograms. It is concluded that acute radiorenography is simple, rapid and safe, and identifies accurately patients with abnormal renal function during attacks of colic, with less risks than excretory urography of causing renal damage or aggravating the pain of renal colic.
 ...
PMID:Acute radiorenography during attacks of renal colic. 663 89

Periappendicitis, a variant of appendicitis, is histologically diagnosed in only about 5% of appendices removed for presumptive acute appendicitis. We herein describe a boy with periappendicitis whose clinical presentation was that of left renal colic and partial left midureteral obstruction. Appendicitis not infrequently simulates right ureteral colic. However, to our knowledge appendiceal inflammation never has been reported to stimulate left ureteral colic. Also, complications of appendicitis are known to cause right ureteral obstruction (rarely bilateral) but have not been reported to cause solitary left ureteral obstruction. We found no previously reported case of solitary left ureteral obstruction from appendiceal inflammation or of periappendicitis causing a serious urologic complication.
 ...
PMID:Periappendicitis presenting as left renal colic. 744 12

The vasopressin analogue, 1-desamino-8-arginine vasopressin (desmopressin), is a potent antidiuretic without the pressor effects of vasopressin. A total of 18 patients with acute renal colic due to stone disease received 40 microgramsf1p4mopressin intranasal spray with encouraging results. There was a significant decrease in the colic pain intensity from an initial mean visual analogue score of 67 +/- 17 mm. to 39 +/- 36 mm. within 30 minutes (p < 0.001). Eight patients (44.4%) had complete pain relief within 30 minutes of administering intranasal desmopressin spray. Nine of 10 patients who required intramuscular diclofenac sodium achieved complete pain relief within another 30 minutes. In other words, when intranasal desmopressin spray was administered before diclofenac sodium, 94.4% of the patients achieved complete pain relief and were discharged home. The mechanism of analgesic action of desmopressin in renal colic is uncertain. At the peripheral level, desmopressin may alleviate the acute renal colic through its potent antidiuretic effect or by relaxing the renal pelvic and ureteral smooth muscles. The central analgesic effect of desmopressin by stimulating the release of the hypothalamic beta-endorphin is proposed. We conclude that intranasal desmopressin spray can be used successfully in the treatment of renal colic. It may also replace prostaglandin synthetase inhibitors in treating renal colic with the advantage of avoiding the potential side effects. Further studies are needed to investigate whether the combination of desmopressin with analgesics or spasmolytic drugs offers competitive results compared with those achieved by prostaglandin synthetase inhibitors in the treatment of renal colic.
 ...
PMID:Treatment of renal colic by desmopressin intranasal spray and diclofenac sodium. 771 52


1 2 3 4 5 Next >>