Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152031 (swollen joints)
 535 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ASAH 12.4
CARF 10.1
SLCO2A1 9.9
IL-12B 9.7
HPGD 9.6
PAD3 9.6
CCP 9.6
FLIR 9.4
PAD2 9.3
DLT 9.3
rheumatoid factor 8.9
Fez 8.9
CCP2 8.8
ESR 8.7
HAS1 8.4
ACR 8.3
matrix metalloproteinase 3 8.2
psoriasis-associated 8.2
HAS3 8.2
Neutral endopeptidase 8.2
stromelysin 8.1
HLA-DRB 8.0
cystatin A 7.9
synaptojanin 7.9
aquaporin 1 7.8
SASP 7.8
hyaluronan synthase 7.8
PAD4 7.8
FLS 7.8
IMF 7.7
IL1A 7.7
CRP 7.7
4 domains 7.7
acid ceramidase 7.6
chitotriosidase 7.5
C-reactive protein 7.4
Rheumatoid factor 7.3
ARA 7.3
cathepsin H 7.2
CIA 7.1
Aggrecan 7.1
COMP 7.1
RCP 7.1
Interleukin-15 7.0
HAS2 7.0
PTPN22 7.0
IL-1ra 6.9
YKL-40 6.9
period 2 6.9
DBM 6.8
ankylosing spondylitis 6.7
Interferon gamma 6.7
PIP 6.6
PLT 6.6
CIC 6.6
alpha1-acid glycoprotein 6.6
MMP-3 6.5
PME 6.5
angiopoietin-2 6.5
CPM 6.4
IL1B 6.4
Patched 6.4
eosinophil peroxidase 6.4
NOS3 6.3
BPI 6.3
type II collagen 6.3
DIP 6.3
FRG 6.3
beta II 6.2
CD4 molecule 6.2
vascular cell adhesion molecule 1 6.2
B lymphocyte stimulator 6.2
DR1 6.2
CXCR5 6.1
PEF 6.1
metallopeptidase 6.0
CXCL13 6.0
B13 5.9
serum amyloid A 5.9
Smoothened 5.8
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Disease
Chlamydial polyarthritis 15.9
Periarticular calcification 14.5
Arthritis mutilans 13.1
Oligoarthritis 12.4
Hemorrhagic enteritis 11.4
Poncet's disease 11.0
Steinbrocker 10.2
Hypertrophic pulmonary osteoarthropathy 10.2
Inflammatory disease 9.8
Bone marrow edema 9.7
sialic acid storage disease 9.6
ectoparasitism 9.5
polyarticular arthritis 9.4
Larsen 9.4
Jaccoud 9.3
dactylitis 9.2
Gouty arthritis 9.2
psoriatic arthritis 9.1
Achilles tendinitis 9.0
enthesopathy 9.0
polyarthritis 8.9
rheumatism 8.8
pyelitis 8.7
rheumatoid arthritis 8.5
tophi 8.5
nasopharyngitis 8.5
monoarthritis 8.5
polyarthralgia 8.4
enthesitis 8.4
juvenile rheumatoid arthritis 8.2
synovitis 8.2
acute arthritis 8.2
onychodystrophy 8.1
Parvovirus B19 infection 8.1
nail disease 8.1
infectious arthritis 8.1
Septic arthritis 8.0
sickle cell crisis 8.0
periarthritis 7.9
CAE 7.9
spondyloarthropathy 7.7
popliteal cyst 7.7
tenosynovitis 7.7
Scheuermann's disease 7.7
autoimmune lymphoproliferative syndrome 7.6
Farber 7.5
dandruff 7.5
PDP 7.5
joint effusion 7.4
glutaric aciduria 7.4
SD1 7.3
DBM 7.3
Felty's syndrome 7.3
Still's disease 7.3
borreliosis 7.2
FFI 7.2
Brucella suis 7.2
Arthus reaction 7.2
hypertrophic osteoarthropathy 7.1
chronic tonsillitis 7.1
bursitis 7.0
osteochondrosis 6.9
periostitis 6.9
osteoarthropathy 6.9
arthritis 6.8
inflammatory joint disease 6.8
ankylosing spondylitis 6.8
PCC 6.8
ISH 6.7
laryngitis 6.6
pityriasis versicolor 6.6
aphthous stomatitis 6.5
cheilitis 6.5
localized infection 6.4
septic arthritis 6.4
microcytic anemia 6.3
rash 6.3
Rosai-Dorfman disease 6.3
anterior uveitis 6.3
molluscum contagiosum 6.3
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Symptom
swollen joints 15.9
feeling feverish 14.3
neurological pain 11.0
epigastric distress 10.3
Grimace 9.8
unwanted hair 9.8
Pain at rest 9.5
hand pain 9.2
Musculoskeletal symptoms 9.1
Severe pain 8.5
Flare 8.4
generalized pain 8.2
stomach pain 7.9
clubbing 7.6
Tenderness 7.3
arthralgia 7.1
arm pain 6.9
Gastrointestinal symptoms 6.7
rales 6.5
heartburn 6.4
livedo 6.1
Stiffness 5.9
dry skin 5.9
epigastric pain 5.7
decreased appetite 5.7
nasal discharge 5.4
back pain 5.3
physical appearance 5.3
pain 5.1
lethargy 5.0
fever of unknown origin 4.8
hepatosplenomegaly 4.8
hopelessness 4.7
tachypnea 4.5
dry eye 4.5
asthenia 4.5
shoulder pain 4.4
knee pain 4.4
hoarseness 4.3
dizziness 4.2
discomfort 4.0
nausea 3.9
discomfort 3.9
chills 3.8
fatigue 3.8
erythema 3.8
cough 3.6
shortness of breath 3.5
Ill 3.4
diarrhea 3.2
respiratory distress 3.2
myalgia 3.2
tinnitus 3.2
anorexia 3.1
vertigo 3.1
headache 2.7
nausea and vomiting 2.6
splenomegaly 2.6
weakness 2.2
overweight 2.2
functional recovery 2.1
dyspnea 2.1
chest pain 1.8
analgesia 1.1
abdominal pain 0.9
vomiting 0.9
Drug
Fenoprofen calcium 11.9
Indoprofen 11.5
Periactin 11.4
Pirprofen 10.8
Bucillamine 10.6
Etodolac 10.5
Fenbufen 10.3
Fenoprofen 9.9
Gold sodium thiomalate 9.5
Auranofin 9.5
Abatacept 9.2
Isoprinosine 9.1
BLyS 8.2
Anakinra 7.9
Voltaren 7.9
Clodronate 7.9
Adalimumab 7.8
FLP 7.8
Tocilizumab 7.1
Diclofenac sodium 7.1
IL-1ra 7.0
EHDP 6.9
Infliximab 6.7
Infliximab 6.7
CPM 6.6
CIA 6.2
Aprotinin 6.0
Doxycycline 5.8
Honey 5.5
Prednisolone 5.3
Check 4.9
ADR 4.9
-deoxyadenosine 4.8
DMI 4.8
Dakar 4.8
Rituximab 4.4
niacin 4.0
CTX 3.4
CTX 3.4
CAM 3.4
IL-2 2.6
CTX 2.5
lactose 1.8
Asthma 1.2
IFN-gamma 1.0
Monit 0.8
Dermatol -1.1
Enzyme
cathepsin H 7.3
interstitial collagenase 7.0
CPM 6.5
MMP-3 6.4
matrix metalloproteinase 9 5.8
cathepsin K 5.0
thioredoxin reductase 4.6
cathepsin B 3.8
MMP 3.8
IKK 3.6
ceruloplasmin 3.6
adenosine deaminase 3.5
adenosine deaminase 3.5
collagenase 3.3
thymidine kinase 3.0
beta-glucuronidase 3.0
lipoxygenase 2.8
CD10 2.6
lysozyme 2.5
phosphatidylinositol 3-kinase 2.4
phospholipase A2 2.1
alkaline phosphatase 1.9
phosphodiesterase 1.7
lactate dehydrogenase 1.0
thrombin 0.8
mitogen-activated protein kinase 0.3
peroxidase -0.1
ERK -0.7
Compound
Cyproheptadine hydrochloride 11.7
HAQ 11.4
Sinomenine 8.7
CCP 8.6
Mefenamic acid 8.3
Hearts 7.9
Etanercept 7.6
Etretinate 7.5
Meloxicam 7.5
DBM 7.3
DBM 7.3
Emery 7.3
EHDP 7.1
Sulfasalazine 7.0
Cortisone 7.0
BAS 6.9
Diclofenac 6.8
Sudan I 6.8
Naproxen 6.6
PYR 6.5
Sulforaphane 6.3
AFC 6.3
Levamisole 6.2
Pentoxifylline 6.2
IPA 6.2
Methotrexate 6.2
IPA 6.2
IPA 6.1
IPA 6.1
CAN 6.1
ANCA 6.0
Minocycline 6.0
Bromocriptine 5.8
Doxycycline 5.8
25-dihydroxycholecalciferol 5.7
APAP 5.5
Uric acid 5.4
Prednisolone 5.3
DPA 5.3
DPA 5.3
DPA 5.3
DPA 5.3
DPA 5.3
APS 4.8
Penicillin 4.8
MTX 4.8
DMI 4.7
DMI 4.7
Parenteral 4.6
Cyclosporine 4.5
Penicillin 4.5
Methicillin 4.3
COX 4.2
ASA 3.9
PMA 3.9
hyaluronic acid 3.8
ANA 3.8
ANA 3.8
PGA 3.7
TNF 3.7
hexose 3.3
hexose 3.3
hexose 3.3
PMA 3.3
ADR 3.3
propionic acid 3.2
propionic acid 3.2
Diazepam 3.2
Heparin 3.2
Vitamin D 3.2
Isoproterenol 3.1
DTPA 3.1
prostaglandin E1 3.0
PGE 2.8
hexose 2.8
Collagen 2.7
guanidine 2.7
isopropanol 2.6
Cholesterol 2.6
CTX 2.5
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