Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152030 (skin irritation)
 2,146 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
OR2B3 13.9
KIAA0368 12.3
ME6 11.9
KIAA0117 11.9
TRIM10 11.3
TRIM40 11.1
PAOX 10.1
ribosomal protein L17 9.7
EURL 9.6
RANTES chemokine 9.5
Protocadherin-1 9.3
TRIM31 9.3
HSP70B' 9.1
calmodulin-like skin protein 9.1
PHK 9.0
ENX 8.8
ITPR3 8.8
hyaluronan synthase 1 8.7
Skin-derived antileukoproteinase 8.6
NRU 8.5
DPK 8.5
B2A 8.4
NSD3 8.3
IER3 8.0
Che-1 7.9
PSMB9 7.8
succinate semialdehyde dehydrogenase 7.8
nuclear transporter 7.6
hairless 7.5
LD5 7.5
Dermatopontin 7.4
HLA-DPA1 7.4
CRABP2 7.4
DNA-directed RNA polymerase 7.3
PASP 7.3
CLP 7.1
Involucrin 7.1
TIS) 7.1
RHS 7.1
SIT 7.0
excision repair protein 7.0
FOSL1 7.0
Nectin-4 6.9
HED 6.9
TTD 6.9
aquaporin 3 6.8
SLS 6.8
HDS 6.8
AAA 6.8
HRI 6.7
SLN 6.7
tyrosinase-related protein 2 6.7
C15 6.7
involucrin 6.6
TAPS 6.6
SHS 6.6
TIP 6.6
EphB3 6.5
MICE 6.5
cytokeratin 1 6.5
ES1 6.4
aFGF 6.3
ST7 6.3
CEACAM6 6.3
histidase 6.3
aquaporin-3 6.3
psoriasis-associated 6.2
CIR 6.1
TSD 6.1
SP4 6.1
peroxiredoxin 1 6.1
HMGIC 6.1
ASK 6.1
MEA 6.0
adipose differentiation-related protein 6.0
HSP70-1 5.9
Cyclophilin 5.9
HMT 5.9
fra-1 5.9
TCH 5.8
more...
Disease
Bacterial folliculitis 13.9
Harara 13.9
Comedonal acne 12.3
Cumulative irritant contact dermatitis 12.3
Nodulocystic acne 11.5
Gastrocutaneous fistula 11.5
photoallergy 11.2
Irritant contact dermatitis 10.5
Demodex folliculitis 10.5
MRSA wound infection 10.3
Rebound hypertension 10.3
Primary focal hyperhidrosis 9.6
Occupational dermatitis 8.9
Parastomal hernia 8.4
Phototoxicity 8.4
oxyuriasis 8.3
pseudofolliculitis barbae 8.2
Hand eczema 8.1
melasma 7.9
photokeratitis 7.8
Anal canal 7.8
chafing 7.8
acne vulgaris 7.7
Harley 7.7
adult HD 7.6
skin hypersensitivity 7.5
sick building syndrome 7.3
Myrmecia 7.3
venous stasis ulcers 7.1
Dermal 7.1
RHS 7.0
Contact Dermatitis 7.0
acne 7.0
EEC 6.9
Metabolic bone disease 6.9
SLS 6.9
SLS 6.8
pompholyx 6.8
AAA 6.8
Photosensitization 6.7
mallet finger 6.7
SGS 6.6
guttate psoriasis 6.6
head lice 6.6
SHS 6.6
SHS 6.5
hypervitaminosis 6.5
dermatitis 6.3
SGS 6.3
rosacea 6.3
macromastia 6.3
claustrophobia 6.2
eye infection 6.2
iritis 6.2
pruritus 5.9
vaginal atrophy 5.9
LAD2 5.8
MDI 5.7
Mastocytosis 5.6
occupational disease 5.6
pityriasis versicolor 5.6
Spraying 5.6
DIA 5.6
eczema 5.6
Horner syndrome 5.5
larva migrans 5.5
hypohidrosis 5.5
psoriasis 5.5
body lice 5.5
ST8 5.5
EPI 5.4
ERS 5.3
ICH 5.3
tinea pedis 5.3
Hyperplasia 5.2
abdominal aortic aneurysm 5.2
Overactive bladder 5.2
hyperkeratosis 5.2
herpes labialis 5.2
Papilloma 5.1
more...
Symptom
skin irritation 13.9
Nasal discomfort 12.9
skin irritant 11.9
inflammation of the vulva 11.3
feeling faint 10.3
Breast tenderness 9.8
skin impairment 9.4
change in skin color 9.2
throat irritation 8.4
Ear swelling 7.9
unwanted hair 7.8
erythema 7.8
Skin symptoms 7.7
Urinary symptoms 7.6
skin damage 7.5
dry skin 7.3
catarrh 7.3
stump pain 7.0
frequent urination 6.4
scaly skin 6.4
prostration 6.3
nasal congestion 6.3
abnormal breathing 6.1
tingling 5.9
Burning 5.6
hot flushes 5.6
chest tightness 5.3
irregular bleeding 5.3
rhinorrhea 5.0
Respiratory symptoms 5.0
discomfort 4.9
discomfort 4.8
hot flashes 4.8
sneezing 4.5
drooling 4.5
nasal discharge 4.4
sore throat 4.4
physical appearance 4.3
dizziness 4.2
menopausal symptoms 4.2
muscle cramps 4.0
dysesthesia 4.0
otalgia 3.9
chronic cough 3.9
flushing 3.8
dysuria 3.6
chronic constipation 3.5
tonic-clonic seizure 3.5
Neuropathic pain 3.4
snoring 3.4
nausea 3.2
spasticity 3.2
abdominal discomfort 3.1
neuralgia 3.1
memory loss 3.0
cough 3.0
nausea and vomiting 2.9
blurred vision 2.8
bradykinesia 2.7
headache 2.5
sleepiness 2.5
shortness of breath 2.5
pain 2.5
shoulder pain 2.4
knee pain 2.4
hunger 2.4
lethargy 2.4
fatigue 2.4
vomiting 2.4
cancer pain 2.3
dyspnea 2.3
myalgia 2.2
constipation 2.1
chest pain 2.1
angina 2.1
cyanosis 2.0
neck pain 1.9
acute pain 1.9
hemiplegia 1.9
agitation 1.9
more...
Drug
White lotion 13.9
Heptanoic Acid 13.9
Mentha oil 11.9
Cyclomethicone 11.9
Alfuzosin hydrochloride 11.3
Adapalene 10.9
Almond oil 10.9
Stearic Acid 10.9
Tazorac 10.9
Tacalcitol 10.7
Lemon oil 10.5
Diflucortolone valerate 10.4
Dithranol 10.4
Dalacin 10.3
Glyceryl monostearate 10.2
Rupintrivir 10.2
Naphtha 10.1
Iodosorb 10.1
Tetradecane 10.0
Crotamiton 9.9
Lanolin 9.8
Calamine 9.8
Lanolin 9.8
Octocrylene 9.7
ENX 9.5
Salicylic Acid 9.5
Evra 9.5
Carbopol 940 9.4
Betamethasone valerate 9.2
Arachidonic Acid 9.2
Mycostatin 9.2
Avobenzone 9.2
Cinnamon oil 8.8
Carbopol 934P 8.8
Tween 85 8.8
Petrolatum 8.7
Clobetasol propionate 8.6
Sertaconazole 8.6
Dalacin 8.6
Encore 8.5
Span 60 8.5
Calcipotriol 8.5
Diltiazem hydrochloride 8.2
Creosote 8.2
Polysorbate 20 8.0
Lornoxicam 8.0
Profenid 7.9
Retinoic Acid 7.9
Dodecyl Sulfate 7.7
Cremophor RH40 7.7
Limonene 7.7
Xanthan gum 7.7
Velban 7.6
Catapres 7.6
Aceclofenac 7.5
Timolol maleate 7.4
Prograf 7.4
Valdecoxib 7.4
Tramal 7.2
Coconut oil 7.2
Menthol 7.1
Cinnarizine 7.0
Dutasteride 7.0
Red ginseng 7.0
Rhubarb 6.8
Hyperforin 6.8
Timolol 6.7
Vinpocetine 6.7
Acitretin 6.6
Corn oil 6.6
Lactic Acid 6.6
Bentonite 6.4
Gemzar 6.3
Camphor 6.3
Camphor 6.2
Lupron 6.2
Atomoxetine 6.1
Cremophor EL 6.1
Diclofenac sodium 6.1
Talc 6.1
more...
Enzyme
benzophenone synthase 9.9
mutanase 8.2
histidase 6.0
succinic semialdehyde dehydrogenase 5.6
HCS 5.2
3C protease 4.9
CYP27A1 4.8
MTD 4.6
tyrosinase 4.6
HDR 4.6
MCS 4.3
PAL 4.2
GABA transaminase 4.2
phosphorylase kinase 4.1
SCS 3.9
PAL 3.8
sorbitol dehydrogenase 3.8
flavin-containing monooxygenase 3.7
arylsulfatase 3.6
cholinesterase 3.4
chalcone synthase 3.3
ornithine decarboxylase 3.2
leucine aminopeptidase 3.2
DTA 3.1
PTA 3.1
ornithine transcarbamylase 3.1
prostaglandin synthetase 3.0
adenylate kinase 2.9
DCF 2.9
lipoxygenase 2.8
acetylcholinesterase 2.8
papain 2.8
matrix metalloproteinase 9 2.7
matrix metalloproteinase 2 2.7
transglutaminase 2.6
lactate dehydrogenase 2.6
SPC 2.5
asparaginase 2.5
aspartate aminotransferase 2.5
AST 2.3
elastase 2.3
sulfatase 2.2
acid phosphatase 2.2
alanine aminotransferase 2.2
prostate-specific antigen 2.1
collagenase 2.0
thymidine kinase 2.0
MMP 1.8
CAD 1.8
aldehyde dehydrogenase 1.8
aldehyde dehydrogenase 1.8
CAD 1.7
aldehyde dehydrogenase 1.7
CAD 1.7
deaminase 1.5
aldehyde dehydrogenase 1.5
glucose oxidase 1.5
glyceraldehyde-3-phosphate dehydrogenase 1.4
calcineurin 1.4
lipase 1.3
CYP3A4 1.2
aldehyde dehydrogenase 1.2
cellulase 1.1
ACS 1.1
MAP 1.0
xanthine oxidase 0.8
ERK 0.8
plasmin 0.7
gamma-glutamyl transpeptidase 0.7
transcriptase 0.6
glutathione reductase 0.6
monoamine oxidase 0.5
chymotrypsin 0.4
phosphatidylinositol 3-kinase 0.4
RNA polymerase 0.3
superoxide dismutase 0.0
mitogen-activated protein kinase -0.1
peroxidase -0.1
DNA polymerase -0.2
ACE -0.3
more...
Compound
4-Isopropylcatechol 13.9
2-phenoxyethyl propionate 13.9
Hexadecanolide 13.9
2-heptylcyclopentanone 13.9
2-methyl-4-phenyl-2-butanol 13.9
Dihydroisojasmone 13.9
12-Oxahexadecanolide 13.9
Anisyl propionate 13.9
2-phenylethyl propionate 13.9
2,4-dimethylbenzyl acetate 13.9
Benzyl isobutyrate 13.9
2-phenylpropyl acetate 13.9
2-phenylethyl butyrate 13.9
2-phenylethyl formate 13.3
Phenoxyethyl isobutyrate 13.3
3-phenylpropyl acetate 12.9
Disperse Blue 7 12.9
3-Phenylpropyl isobutyrate 12.9
1,1-dimethyl-2-phenylethyl acetate 12.9
Cyclopentadecanolide 12.3
N-Stearoylethanolamine 12.3
C9H10O3 11.9
2-tert-butyl-5-methylphenol 11.9
Hexylcinnamaldehyde 11.9
Trithiocyanuric acid 11.9
2-(4-methylphenoxy)ethanol 11.9
p-Menth-1-ene 11.9
1-oxaspiro[2.5]octane 11.9
C10H12O2 11.9
Acid Violet 43 11.9
benzyl formate 11.9
allyl phenoxyacetate 11.9
C10H10O4 11.5
Musk T 11.3
benzyl butyrate 11.3
Anisyl alcohol 11.1
1,2-decanediol 11.1
C10H14O 11.1
cyclopentadecanone 11.0
Mebeverine hydrochloride 10.7
1-tridecanol 10.7
benzyl propionate 10.5
Orobol 10.5
cis-Jasmone 10.4
Dithranol 10.4
Daphnoretin 10.3
3-methyl-3-pentanol 10.3
Tazarotene 10.3
Dexpanthenol 10.1
TCPA 10.0
Norephedrine 10.0
Geranyl acetate 9.9
cyclohexylbenzene 9.8
Phenmetrazine 9.8
cyclohexylbenzene 9.8
9-octadecen-1-ol 9.8
1-bromohexane 9.8
tetrachloroplatinum 9.7
Diphenyl ether 9.7
2-phenyl-2-propanol 9.7
hexyl nicotinate 9.6
DEPA 9.5
1,2-pentanediol 9.5
1,2-octanediol 9.5
cyclopentanone 9.5
cyclopentanone 9.5
cyclopentanone 9.4
cyclopentanone 9.4
C6H8N2 9.4
Menthone 9.3
Methyl isocyanate 9.2
Fusarenon-X 9.2
Myristicin 9.2
DETP 9.2
3-phenyl-1-propanol 9.2
Mesoridazine 9.2
Fucosyllactose 9.1
Oxamyl 9.0
isopropyl palmitate 8.9
3-methyl-3-buten-1-ol 8.9
more...