Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152030 (skin irritation)
2,146 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 177
hairless 44
cytokine 37
collagen 23
AAA 22
DSC 18
C15 18
all-trans 17
IL-8 16
tyrosinase 15
keratin 14
IL-6 14
SDS 14
hemoglobin 13
NMR 13
Mol 12
lactate dehydrogenase 12
ATR 11
ACS 11
tap 9
IgE 9
insulin 9
involucrin 9
serum albumin 9
Pseudomonas 8
tumor necrosis factor 8
TNF-alpha 7
IL-1 7
C17 7
TEM 7
TNF 7
scratch 7
EPI 6
acetylcholinesterase 6
albumin 6
CO2 6
substance P 6
PDI 5
CLP 5
ANOVA 5
monocyte chemoattractant protein-1 5
PVA 5
esterase 5
granulocyte 5
thymus 5
TPA 5
FSH 5
SLN 5
C18 5
aspartate aminotransferase 5
alanine aminotransferase 5
interleukin-6 5
interleukin-1 receptor antagonist 4
EPA 4
IL-1 alpha 4
acid phosphatase 4
LPS 4
superoxide dismutase 4
GSH 4
xenobiotic 4
glucosamine 4
TIS) 4
NRU 4
ESI 4
SLS 4
lipoxygenase 4
inducible nitric oxide synthase 4
ornithine decarboxylase 4
p38 4
filaggrin 4
matrix metalloproteinase 4
CAS 4
COX-2 4
glucan 4
kit 4
mast cell 3
PEG 3
lipase 3
K10 3
MET 3
more...
Disease
Contact Dermatitis 130
dermatitis 74
psoriasis 62
pruritus 60
acne 58
cancer 50
tumor 45
acne vulgaris 37
photoallergy 31
atopic dermatitis 30
skin disease 23
abdominal aortic aneurysm 22
AAA 22
plaque 20
hypertension 19
depression 19
Dermal 19
diabetes 18
eczema 18
skin cancer 18
melanoma 17
SDS 14
SEM 12
cold 11
incontinence 11
carcinogenesis 10
melasma 10
lymphoma 10
Irritant contact dermatitis 10
stroke 9
asthma 9
EEC 9
carcinoma 8
urticaria 8
breast cancer 8
rosacea 8
hyperkeratosis 8
rash 8
Colon 7
osteoarthritis 7
osteoporosis 7
TEM 7
Colon 7
Colon 7
TEM 7
influenza 7
arthritis 7
cornea 7
sepsis 6
ICH 6
hypogonadism 6
squamous cell carcinoma 6
hypercalcemia 6
rheumatoid arthritis 6
EPI 6
Parkinson's disease 6
infestation 6
keratosis 5
skin hypersensitivity 5
prostate cancer 5
hypoglycemia 5
candidiasis 5
xerostomia 5
malaria 5
dehydration 5
tumorigenesis 5
sepsis 5
sleep disturbances 5
HIV 5
cardiovascular disease 5
incontinence 5
conjunctivitis 5
hernia 4
leukemia 4
Rectum 4
chronic bronchitis 4
decubitus 4
abortion 4
SLS 4
gynecomastia 4
more...
Symptom
skin irritation 2146
erythema 193
pain 98
skin irritant 47
discomfort 47
discomfort 44
headache 22
skin damage 19
fatigue 18
nausea 15
anesthesia 14
diarrhea 14
cough 13
dizziness 12
vomiting 11
dry skin 11
dyspnea 9
seizures 8
nasal congestion 6
angina 6
flushing 6
sleepiness 5
rhinorrhea 5
tingling 5
nausea and vomiting 5
chest pain 5
analgesia 5
throat irritation 4
sore throat 4
hot flushes 4
spasticity 4
weakness 3
back pain 3
agitation 3
sneezing 3
constipation 3
syncope 2
dysuria 2
tremor 2
Ill 2
memory loss 2
insomnia 2
ataxia 2
menopausal symptoms 2
distraction 2
thinning 2
hunger 2
overweight 2
catarrh 2
hot flashes 2
myalgia 2
chest tightness 2
snoring 2
collapse 2
physical appearance 2
shortness of breath 2
nasal discharge 2
lethargy 2
prostration 2
chronic cough 2
skin impairment 1
scaly skin 1
feeling faint 1
drooling 1
tonic-clonic seizure 1
anorexia 1
abnormal breathing 1
arthralgia 1
otalgia 1
knee pain 1
bradykinesia 1
acidity 1
blurred vision 1
Skin symptoms 1
Neuropathic pain 1
shoulder pain 1
inflammation of the vulva 1
myoclonus 1
acute pain 1
Respiratory symptoms 1
more...
Drug
Dermatol 152
Dithranol 14
Adapalene 10
nitroglycerin 9
Retinoic acid 8
EE2 7
lysine 6
Retinoic Acid 6
Triclosan 6
Encore 6
EPI 6
vitamin E 5
caffeine 5
Leaf 5
Limonene 5
Carbopol 940 4
Aloe 4
ZnO 4
Span 60 4
Clobetasol propionate 4
Calcipotriol 4
Gel 3
Carbopol 934P 3
EPA 3
Clonidine 3
Menthol 3
Capsicum 3
Cremophor EL 3
Diphenhydramine 3
Timolol 3
Ethanol 3
MAP 3
Tacrolimus 3
ascorbate 2
TES 2
MRC 2
ADM 2
Tacalcitol 2
Salicylate 2
MEA 2
Tween 85 2
Indomethacin 2
AZT 2
ROC 2
lactose 2
ROS 2
Imiquimod 2
AZT 2
ENT 2
Xanthan gum 2
ALA 2
Apomorphine 2
Photofrin 2
ETA 2
IPM 2
CAM 2
Prograf 2
Vitamin E 2
Diclofenac sodium 2
ampicillin 2
Tazorac 2
Evra 1
PMPA 1
Valdecoxib 1
Crotamiton 1
Check 1
Salicylic Acid 1
Corn oil 1
Asn 1
Glycyrrhiza 1
Acacia 1
Naphtha 1
Taxol 1
Alliance 1
Camphor 1
Velban 1
Atomoxetine 1
Miltefosine 1
Zein 1
Betamethasone valerate 1
more...
Enzyme
tyrosinase 15
acetylcholinesterase 13
lactate dehydrogenase 12
ACS 11
ERK 11
cholinesterase 9
alanine aminotransferase 8
aspartate aminotransferase 8
mitogen-activated protein kinase 6
collagenase 5
ornithine decarboxylase 4
acid phosphatase 4
superoxide dismutase 4
peroxidase 4
lipoxygenase 4
papain 3
elastase 3
calcineurin 3
lipase 3
RNA polymerase 3
trypsin 2
catalase 2
focal adhesion kinase 2
thymidine kinase 2
protein kinase C 2
transglutaminase 2
PAL 2
AST 2
PAL 2
prostate-specific antigen 2
phosphorylase kinase 1
CAD 1
aldehyde dehydrogenase 1
glutathione S-transferase 1
glyceraldehyde-3-phosphate dehydrogenase 1
aldehyde dehydrogenase 1
matrix metalloproteinase 9 1
CYP3A4 1
phosphatidylinositol 3-kinase 1
leucine aminopeptidase 1
prostaglandin synthetase 1
3C protease 1
ACE 1
aldehyde dehydrogenase 1
transcriptase 1
MCS 1
chalcone synthase 1
aldehyde dehydrogenase 1
glucose oxidase 1
thrombin 1
benzophenone synthase 1
proteasome 1
alkaline phosphatase 1
phosphodiesterase 1
SPC 1
CYP27A1 1
xanthine oxidase 1
asparaginase 1
CAD 1
arylsulfatase 1
CAD 1
ornithine transcarbamylase 1
glutathione reductase 1
monoamine oxidase 1
plasmin 1
ATPase 1
DCF 1
sulfatase 1
aldehyde dehydrogenase 1
flavin-containing monooxygenase 1
cellulase 1
GABA transaminase 1
HDR 1
adenylate kinase 1
MMP 1
creatine kinase 1
PTA 1
matrix metalloproteinase 2 1
SCS 1
DNA polymerase 1
more...
Compound
water 314
Dec 194
sodium 165
ethanol 118
Clin 92
sulfate 85
acetate 69
MTT 58
retinoic acid 41
carbonate 38
DNA 38
phosphate 36
benzene 31
PEG 30
propylene glycol 28
SDS 27
propylene glycol 26
oxygen 24
glucose 23
acetone 22
AAA 22
silver 21
Tween 80 21
cyclopentanone 20
cyclopentanone 20
cyclopentanone 20
cyclopentanone 20
cyclopentanone 20
salt 20
calcium 18
glycerol 17
urea 17
toluene 15
nitrogen 14
formaldehyde 14
titanium 14
Dithranol 14
CO2 13
hyaluronic acid 13
hydroquinone 13
bromide 12
isopropanol 12
hydrogen 12
salicylic acid 12
DMSO 12
nitrate 11
isopropyl myristate 11
aldehyde 11
formaldehyde 11
ACS 11
ACS 11
iodine 11
zinc 11
phenol 11
ammonium 11
methanol 10
copper 10
PEG 10
tetradecane 9
acetic acid 9
phosphoric acid 9
aluminum 9
Pluronic 9
Off 9
Sodium 9
nickel 9
chromium 9
Tazarotene 9
vinyl 9
Testosterone 8
aldehyde 8
acrylic acid 8
arginine 8
stearic acid 8
HCl 8
retinol 8
APV 8
dodecane 7
dichloromethane 7
betaine 7
more...