Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0152030 (skin irritation)
 2,146 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 177
hairless 44
cytokine 37
collagen 23
AAA 22
C15 18
DSC 18
all-trans 17
IL-8 16
tyrosinase 15
IL-6 14
keratin 14
SDS 14
NMR 13
hemoglobin 13
lactate dehydrogenase 12
Mol 12
ATR 11
ACS 11
tap 9
insulin 9
serum albumin 9
IgE 9
involucrin 9
tumor necrosis factor 8
Pseudomonas 8
scratch 7
TEM 7
IL-1 7
TNF-alpha 7
TNF 7
C17 7
substance P 6
albumin 6
CO2 6
EPI 6
acetylcholinesterase 6
ANOVA 5
esterase 5
monocyte chemoattractant protein-1 5
PDI 5
interleukin-6 5
alanine aminotransferase 5
FSH 5
CLP 5
thymus 5
C18 5
granulocyte 5
PVA 5
aspartate aminotransferase 5
SLN 5
TPA 5
interleukin-1 receptor antagonist 4
superoxide dismutase 4
acid phosphatase 4
filaggrin 4
TIS) 4
GSH 4
glucosamine 4
ornithine decarboxylase 4
ESI 4
NRU 4
p38 4
COX-2 4
SLS 4
xenobiotic 4
inducible nitric oxide synthase 4
IL-1 alpha 4
CAS 4
EPA 4
matrix metalloproteinase 4
lipoxygenase 4
glucan 4
LPS 4
kit 4
PEG 3
myeloperoxidase 3
SIT 3
K10 3
glycoprotein 3
prostate-specific antigen 3
CD1a 3
SPF 3
proliferating cell nuclear antigen 3
HPRT 3
TGA 3
HSP27 3
butyrylcholinesterase 3
Pol 3
mast cell 3
rat) 3
San 3
patched 3
lipase 3
Mil 3
MCM 3
MET 3
SAR 3
Che-1 3
calcineurin 3
olfactory 3
ASC 2
castor 2
IL-18 2
catalase 2
P40 2
microsomal 2
heat shock protein 27 2
PBS 2
aFGF 2
fatty acid binding protein 2
Boc 2
CD4 2
ERK 2
CD1 2
vascular endothelial growth factor 2
CIE 2
NTP 2
TIP 2
ALA 2
intercellular adhesion molecule-1 2
heat shock protein 2
cytochrome P450 2
IL6 2
mouse) 2
HET 2
type I collagen 2
PAL 2
FVIII 2
grit 2
CAM 2
IL-10 2
p38 mitogen-activated protein kinase 2
sex hormone-binding globulin 2
AKT 2
ALP 2
MCP-1 2
MRC 2
CF2 2
PSS 2
aryl hydrocarbon receptor 2
Ki-67 2
She 2
CD45 2
Skin-derived antileukoproteinase 2
IkappaBalpha 2
COX 2
chemokine 2
PPD 2
CXCL10 2
LDH 2
API 2
RANTES 2
AST 2
c-kit 2
EGFR 2
ATP 2
MRI 2
IL-4 2
p65 2
more...
Disease
Contact Dermatitis 130
dermatitis 74
psoriasis 62
pruritus 60
acne 58
cancer 50
tumor 45
acne vulgaris 37
photoallergy 31
atopic dermatitis 30
skin disease 23
abdominal aortic aneurysm 22
AAA 22
plaque 20
depression 19
Dermal 19
hypertension 19
eczema 18
diabetes 18
skin cancer 18
melanoma 17
SDS 14
SEM 12
incontinence 11
cold 11
carcinogenesis 10
Irritant contact dermatitis 10
lymphoma 10
melasma 10
asthma 9
EEC 9
stroke 9
rash 8
hyperkeratosis 8
rosacea 8
urticaria 8
breast cancer 8
carcinoma 8
osteoarthritis 7
influenza 7
Colon 7
TEM 7
Colon 7
TEM 7
Colon 7
osteoporosis 7
arthritis 7
cornea 7
hypercalcemia 6
ICH 6
sepsis 6
Parkinson's disease 6
hypogonadism 6
rheumatoid arthritis 6
squamous cell carcinoma 6
EPI 6
infestation 6
sepsis 5
HIV 5
sleep disturbances 5
tumorigenesis 5
malaria 5
conjunctivitis 5
prostate cancer 5
incontinence 5
skin hypersensitivity 5
hypoglycemia 5
cardiovascular disease 5
keratosis 5
candidiasis 5
dehydration 5
xerostomia 5
GSH 4
peripheral neuropathy 4
Rectum 4
leukemia 4
infertility 4
photosensitivity 4
sleep apnea 4
SLS 4
Rectum 4
chronic bronchitis 4
Rectum 4
papilloma 4
hernia 4
prolapse 4
SLS 4
gynecomastia 4
Rectum 4
head lice 4
decubitus 4
Phototoxicity 4
leishmaniasis 4
occupational disease 4
abortion 4
mole 3
mole 3
rheumatism 3
epilepsy 3
addiction 3
respiratory failure 3
iritis 3
lung cancer 3
thrombocytopenia 3
infectious diseases 3
allergic rhinitis 3
erectile dysfunction 3
dementia 3
forgetting 3
agranulocytosis 3
chronic disease 3
sick building syndrome 3
type 2 diabetes 3
chronic pain 3
aggression 3
cataract 3
multiple sclerosis 3
endometrial hyperplasia 3
warts 3
hypervitaminosis 3
hay fever 3
MDI 3
Klebsiella 3
vitiligo 3
cellulitis 3
schizophrenia 3
lice 3
immunotoxicity 3
scoliosis 3
bladder cancer 3
AIDS 3
pneumonia 3
pneumoconiosis 3
uterus 3
colon cancer 3
tuberculosis 3
SAR 3
chronic obstructive pulmonary disease 2
essential hypertension 2
Nose 2
nosocomial infection 2
leprosy 2
nocturia 2
PAL 2
major depressive disorder 2
coronary artery disease 2
rhinitis 2
toxic shock syndrome 2
fits 2
complex partial seizures 2
coronary heart disease 2
TCP 2
Best 2
folliculitis 2
herpes simplex 2
confusion 2
bronchospasm 2
conjunctiva 2
parkinsonism 2
herpes 2
more...
Symptom
skin irritation 2146
erythema 193
pain 98
skin irritant 47
discomfort 47
discomfort 44
headache 22
skin damage 19
fatigue 18
nausea 15
diarrhea 14
anesthesia 14
cough 13
dizziness 12
dry skin 11
vomiting 11
dyspnea 9
seizures 8
flushing 6
nasal congestion 6
angina 6
sleepiness 5
rhinorrhea 5
tingling 5
analgesia 5
chest pain 5
nausea and vomiting 5
throat irritation 4
sore throat 4
hot flushes 4
spasticity 4
weakness 3
sneezing 3
agitation 3
constipation 3
back pain 3
syncope 2
dysuria 2
tremor 2
Ill 2
memory loss 2
insomnia 2
ataxia 2
collapse 2
myalgia 2
prostration 2
overweight 2
hot flashes 2
thinning 2
chest tightness 2
distraction 2
hunger 2
snoring 2
physical appearance 2
lethargy 2
shortness of breath 2
nasal discharge 2
catarrh 2
menopausal symptoms 2
chronic cough 2
skin impairment 1
scaly skin 1
feeling faint 1
drooling 1
tonic-clonic seizure 1
anorexia 1
abnormal breathing 1
arthralgia 1
otalgia 1
knee pain 1
bradykinesia 1
acidity 1
blurred vision 1
Skin symptoms 1
change in skin color 1
Neuropathic pain 1
shoulder pain 1
hemiplegia 1
frequent urination 1
cancer pain 1
myoclonus 1
acute pain 1
Respiratory symptoms 1
Breast tenderness 1
unwanted hair 1
inflammation of the vulva 1
functional recovery 1
hypothermia 1
irregular bleeding 1
wheezing 1
stump pain 1
Nasal discomfort 1
abdominal discomfort 1
low back pain 1
Urinary symptoms 1
neuralgia 1
abdominal pain 1
Burning 1
muscle cramps 1
neck pain 1
Welt 1
spasm 1
splenomegaly 1
Ear swelling 1
dysesthesia 1
chronic constipation 1
cyanosis 1
Drug
Dermatol 152
Dithranol 14
Adapalene 10
nitroglycerin 9
Retinoic acid 8
EE2 7
EPI 6
Encore 6
Retinoic Acid 6
lysine 6
Triclosan 6
Limonene 5
vitamin E 5
caffeine 5
Leaf 5
Calcipotriol 4
Span 60 4
ZnO 4
Aloe 4
Clobetasol propionate 4
Carbopol 940 4
Tacrolimus 3
Cremophor EL 3
Diphenhydramine 3
Gel 3
Menthol 3
Timolol 3
Carbopol 934P 3
Capsicum 3
MAP 3
Clonidine 3
Ethanol 3
EPA 3
Vitamin E 2
MEA 2
Indomethacin 2
Salicylate 2
ROC 2
lactose 2
Prograf 2
IPM 2
TES 2
Photofrin 2
ampicillin 2
ENT 2
ETA 2
Xanthan gum 2
ascorbate 2
Diclofenac sodium 2
Apomorphine 2
ALA 2
CAM 2
AZT 2
ADM 2
Imiquimod 2
MRC 2
Tacalcitol 2
AZT 2
Tween 85 2
ROS 2
Tazorac 2
Acitretin 1
Evra 1
CaCl2 1
Petrolatum 1
Crotamiton 1
Check 1
Posture 1
Clofibrate 1
Salicylic Acid 1
CTC 1
Bentonite 1
Corn oil 1
Doxycycline 1
Glycyrrhiza 1
Arachidonic Acid 1
ENX 1
Naphtha 1
Lanolin 1
Alliance 1
Camphor 1
Fentanyl 1
Fluorescein 1
Zein 1
Profenid 1
Atomoxetine 1
Betamethasone valerate 1
Papain 1
niacin 1
Polysorbate 20 1
Diflucortolone valerate 1
Avobenzone 1
citric acid 1
Allergen 1
Hydrochlorothiazide 1
CER 1
Timolol maleate 1
OTC 1
Catapres 1
CTC 1
Talc 1
Vinpocetine 1
Poloxamer 188 1
Octocrylene 1
Dodecyl Sulfate 1
Kaolin 1
White lotion 1
Rutin 1
Lactic Acid 1
Cinnamon oil 1
Aceclofenac 1
L-tyrosine 1
Hyperforin 1
Diltiazem hydrochloride 1
Mycostatin 1
OTC 1
Dasatinib 1
Fluorescein 1
Glyceryl monostearate 1
GEO 1
Gemzar 1
CaCl2 1
PMPA 1
Cardiovasc 1
Fluconazole 1
Tenofovir 1
Voltaren 1
Almond oil 1
Methylene blue 1
Valdecoxib 1
Atropine 1
CSF 1
IL-2 1
Monit 1
Nimesulide 1
Vitamin A 1
Dalacin 1
Asn 1
Lanolin 1
Acacia 1
Camphor 1
Taxol 1
Tetradecane 1
FLP 1
Rupintrivir 1
Velban 1
Cremophor RH40 1
Miltefosine 1
Levonorgestrel 1
Sertaconazole 1
Cyclomethicone 1
CCL 1
Heptanoic Acid 1
Tramal 1
Lornoxicam 1
Peridex 1
Red ginseng 1
Rhubarb 1
BCG vaccine 1
Iodosorb 1
more...
Enzyme
tyrosinase 15
acetylcholinesterase 13
lactate dehydrogenase 12
ACS 11
ERK 11
cholinesterase 9
aspartate aminotransferase 8
alanine aminotransferase 8
mitogen-activated protein kinase 6
collagenase 5
ornithine decarboxylase 4
acid phosphatase 4
lipoxygenase 4
superoxide dismutase 4
peroxidase 4
calcineurin 3
papain 3
lipase 3
elastase 3
RNA polymerase 3
trypsin 2
catalase 2
focal adhesion kinase 2
thymidine kinase 2
AST 2
protein kinase C 2
PAL 2
PAL 2
transglutaminase 2
prostate-specific antigen 2
phosphorylase kinase 1
CAD 1
aldehyde dehydrogenase 1
glutathione S-transferase 1
glyceraldehyde-3-phosphate dehydrogenase 1
aldehyde dehydrogenase 1
matrix metalloproteinase 9 1
CYP3A4 1
phosphatidylinositol 3-kinase 1
leucine aminopeptidase 1
prostaglandin synthetase 1
3C protease 1
ACE 1
aldehyde dehydrogenase 1
transcriptase 1
reverse transcriptase 1
aldehyde dehydrogenase 1
deaminase 1
histidase 1
benzophenone synthase 1
proteasome 1
MAP 1
alkaline phosphatase 1
SPC 1
renin 1
CYP27A1 1
mutanase 1
xanthine oxidase 1
asparaginase 1
CAD 1
arylsulfatase 1
CAD 1
glutathione reductase 1
ornithine transcarbamylase 1
monoamine oxidase 1
plasmin 1
ATPase 1
aldehyde dehydrogenase 1
flavin-containing monooxygenase 1
cellulase 1
GABA transaminase 1
DCF 1
sulfatase 1
creatine kinase 1
MCS 1
HDR 1
adenylate kinase 1
MMP 1
sorbitol dehydrogenase 1
chalcone synthase 1
DTA 1
glucose oxidase 1
thrombin 1
PTA 1
matrix metalloproteinase 2 1
SCS 1
phosphodiesterase 1
DNA polymerase 1
MTD 1
succinic semialdehyde dehydrogenase 1
chymotrypsin 1
HCS 1
gamma-glutamyl transpeptidase 1
Compound
water 314
Dec 194
sodium 165
ethanol 118
Clin 92
sulfate 85
acetate 69
MTT 58
retinoic acid 41
DNA 38
carbonate 38
phosphate 36
benzene 31
PEG 30
propylene glycol 28
SDS 27
propylene glycol 26
oxygen 24
glucose 23
AAA 22
acetone 22
silver 21
Tween 80 21
cyclopentanone 20
salt 20
cyclopentanone 20
cyclopentanone 20
cyclopentanone 20
cyclopentanone 20
calcium 18
glycerol 17
urea 17
toluene 15
Dithranol 14
nitrogen 14
titanium 14
formaldehyde 14
CO2 13
hydroquinone 13
hyaluronic acid 13
DMSO 12
hydrogen 12
salicylic acid 12
bromide 12
isopropanol 12
phenol 11
isopropyl myristate 11
ACS 11
aldehyde 11
nitrate 11
iodine 11
ammonium 11
formaldehyde 11
ACS 11
zinc 11
methanol 10
copper 10
PEG 10
Tazarotene 9
phosphoric acid 9
tetradecane 9
Off 9
chromium 9
Pluronic 9
nickel 9
acetic acid 9
Sodium 9
aluminum 9
vinyl 9
retinol 8
APV 8
Testosterone 8
stearic acid 8
HCl 8
aldehyde 8
arginine 8
acrylic acid 8
TEM 7
5-FU 7
hexadecane 7
PGE 7
lysine 7
His 7
hexane 7
TNF 7
dodecane 7
dichloromethane 7
betaine 7
creatinine 7
nitric oxide 6
adipate 6
G20 6
TPA 6
ethyl acetate 6
naphthalene 6
Tween 20 6
chlorine 6
PVP 6
hydroxide 6
silicon 6
potassium 6
Span 80 6
Testosterone 6
Capsaicin 6
tridecane 6
vitamin D 6
nonane 6
XPA 5
benzoic acid 5
Limonene 5
cysteine 5
TPA 5
chloroform 5
Triton X-100 5
PVA 5
XPA 5
cobalt 5
PVP-I 5
iron 5
vinyl acetate 5
mercury 5
anthracene 5
caffeine 5
Betula 5
Curcumin 5
heptanoic acid 4
Chitosan 4
DMF 4
ammonia 4
GSH 4
25-dihydroxycholecalciferol 4
galactose 4
DBA 4
ABL 4
GSH 4
heptanoic acid 4
pyrene 4
PGE2 4
TEA 4
NH2 4
2-cyclopenten-1-one 4
2-hydroxyethyl 4
Menthol 4
SPF 3
stearic acid 3
hydrazine 3
CCC 3
Dexpanthenol 3
pyrimidine 3
octyl 3
methionine 3
Glycolate 3
1,8-cineole 3
Limonene 3
propionic acid 3
diethyl phthalate 3
octanoic acid 3
Diphenhydramine 3
tyrosine 3
cinnamyl 3
more...