Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0151825 (
bone pain
)
3,118
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
alkaline phosphatase
279
Sep
190
parathyroid hormone
141
She
103
calcitonin
87
granulocyte colony-stimulating factor
87
Mol
69
MRI
54
hemoglobin
53
CSF
47
granulocyte
45
G-CSF
42
PTH
39
prostate-specific antigen
39
FDG
33
RANKL
33
cytokine
32
osteocalcin
32
chronic renal failure
31
RANK
29
non-Hodgkin's lymphoma
28
granulocyte-macrophage colony-stimulating factor
26
Walker
26
osteoprotegerin
26
interferon
25
PSA
25
osteosarcoma
25
MDP
24
type I collagen
24
parathormone
24
acid phosphatase
23
glucocerebrosidase
23
collagen
22
CD34
22
imiglucerase
22
lactate dehydrogenase
20
Calcitonin
19
aromatase
18
C-reactive protein
17
FGF23
17
parathyroid hormone-related protein
17
prostate specific antigen
17
LDH
16
OPG
16
HLA
15
lymphoid
15
GM-CSF
15
LHRH
14
prostatic acid phosphatase
14
ALP
14
somatostatin
13
granulocyte colony stimulating factor
13
TNF
12
cage
12
interleukin-6
12
albumin
12
tumor necrosis factor
12
IL-6
12
IL-1
12
growth hormone
12
IgA
12
MAPK
12
nerve growth factor
11
prolactin
11
ferritin
11
white cell
11
ALL
11
mast cell
11
erythroid
10
reserved
10
interferon-alpha
10
BRAF
10
CD4
10
all-trans
10
interferon alpha
10
macrophage colony-stimulating factor
9
PHEX
9
Men
9
M-protein
9
ATP
9
more...
Disease
cancer
824
tumor
454
bone metastases
422
metastases
383
multiple myeloma
330
hypercalcemia
326
bone disease
313
prostate cancer
289
breast cancer
278
osteoporosis
209
osteomalacia
207
carcinoma
167
anemia
160
PDB
136
hyperparathyroidism
120
spinal cord compression
118
thrombocytopenia
108
leukemia
97
pathological fracture
91
osteomyelitis
82
neutropenia
82
lymphoma
79
Gaucher disease
74
renal failure
71
pruritus
67
bone cancer
61
acute lymphoblastic leukemia
59
rash
56
rickets
56
lung cancer
53
primary hyperparathyroidism
52
lymphadenopathy
51
chronic pain
49
dysplasia
47
metastatic breast cancer
47
adenoma
46
tumor growth
43
arthritis
42
depression
41
sickle cell disease
41
osteosclerosis
39
chronic renal failure
39
wasting
38
vitamin D deficiency
37
osteoarthritis
37
Tumor-induced osteomalacia
36
adenocarcinoma
35
renal insufficiency
35
acute myeloid leukemia
34
Erdheim-Chester disease
34
osteitis
33
Prostate Cancer
32
Schnitzler syndrome
32
renal disease
32
myelodysplastic syndrome
31
leukopenia
31
non-Hodgkin's lymphoma
29
pancytopenia
28
osteosarcoma
28
paraneoplastic syndrome
28
Fanconi syndrome
27
Hodgkin's disease
27
gammopathy
26
myelosuppression
26
hypertension
26
primary tumor
26
hypercalcemia of malignancy
25
PSA
25
renal cell carcinoma
24
rare disease
24
Langerhans cell histiocytosis
24
renal osteodystrophy
24
osteogenesis imperfecta
24
prostatic adenocarcinoma
23
acute leukemia
23
hematologic malignancies
23
periostitis
23
chronic myeloid leukemia
22
proteinuria
22
Fanconi
22
more...
Symptom
bone pain
3118
pain
809
weakness
170
fatigue
131
headache
88
cancer pain
68
arthralgia
66
nausea
62
analgesia
50
myalgia
50
splenomegaly
49
diarrhea
47
back pain
43
vomiting
41
abdominal pain
33
dyspnea
33
hepatosplenomegaly
32
anorexia
25
hepatomegaly
23
collapse
21
flushing
20
Ill
20
constipation
18
nausea and vomiting
17
seizures
15
discomfort
15
discomfort
15
chest pain
15
low back pain
14
insomnia
14
night sweats
14
polyuria
14
asthenia
13
pallor
13
paresthesia
13
anesthesia
12
clubbing
12
lethargy
12
polydipsia
12
cough
12
erythema
11
chills
11
hip pain
11
dizziness
10
prostatism
9
acute pain
9
cachexia
9
fever of unknown origin
8
sleepiness
7
leg pain
7
shortness of breath
7
hemoptysis
6
breakthrough pain
6
knee pain
5
dysuria
5
epigastric pain
5
hoarseness
5
hot flashes
5
tinnitus
5
numbness
5
Neuropathic pain
4
Spots
4
muscle cramps
4
abnormal gait
4
respiratory distress
4
shoulder pain
4
thinning
4
abdominal discomfort
4
dry skin
4
hot flushes
4
paraparesis
4
paresis
4
nasal congestion
4
acidity
3
joint stiffness
3
ataxia
3
Flare
3
vertigo
3
wheezing
3
chronic cough
3
more...
Drug
G-CSF
63
CSF
58
Zoledronic acid
52
Zoledronic acid
47
PTH
39
EHDP
38
Clodronate
24
Filgrastim
18
APD
18
Ibandronate
16
Dermatol
14
Filgrastim
13
Denosumab
13
Aredia
13
SrCl2
11
CTX
10
Dial
10
ascorbate
9
Zoladex
8
Zoladex
8
ICI
7
CTX
7
CTX
7
Leaf
6
MRC
6
Adriamycin
6
Gallium nitrate
5
Salmon calcitonin
5
Lenograstim
5
Cerezyme
4
PMPA
4
Ceredase
4
Adefovir dipivoxil
4
Cerezyme
4
Quadramet
4
Bortezomib
3
VCR
3
Prednisone
3
IFN-gamma
3
caffeine
3
Rituximab
3
p75
3
Estracyt
3
Docetaxel
3
SrCl2
3
lysine
3
IL-1ra
3
Estracyt
3
Lenalidomide
3
Tenofovir disoproxil fumarate
3
Lupron
2
Alliance
2
MAP
2
Taxol
2
Asthma
2
-deoxyadenosine
2
Bonefos
2
Nephron
2
ENT
2
Glucagon
2
Lanthanum carbonate
2
Anakinra
2
Cinacalcet
2
Fosamax
2
Prednisolone
2
PMEA
2
ProstaScint
2
Vinorelbine
2
Skelid
2
Ipriflavone
2
Gefitinib
2
Vindesine
2
Vindesine
2
Spectrum
2
MDS
2
IL-2
2
Skelid
2
Luteinizing
1
Bavituximab
1
Sandostatin
1
more...
Enzyme
alkaline phosphatase
279
prostate-specific antigen
36
lactate dehydrogenase
25
ERK
24
MDP
24
acid phosphatase
23
mitogen-activated protein kinase
23
glucocerebrosidase
19
focal adhesion kinase
8
cathepsin K
8
CD10
6
proteasome
6
prostate-specific membrane antigen
5
aspartate aminotransferase
5
calcineurin
5
protein kinase
5
alanine aminotransferase
4
trypsin
4
creatine kinase
4
ATPase
4
protein kinase C
3
luciferase
3
MEK
3
CaMKII
3
peroxidase
3
elastase
2
monoacylglycerol lipase
2
AST
2
beta-glucosidase
2
BMT
2
beta-glucosidase
2
granzyme B
2
MIP
2
HOA
2
tryptase
2
gamma-glutamyl transpeptidase
2
reverse transcriptase
1
urokinase-type plasminogen activator
1
LMT
1
MAT
1
SMP
1
PARP
1
glutamate dehydrogenase
1
pepsin
1
inositol 3-kinase
1
isopeptidase
1
HDR
1
protein phosphatase 2A
1
caspase-3
1
renin
1
lipase
1
legumain
1
thymidine phosphorylase
1
superoxide dismutase
1
ACE
1
IKK
1
thrombin
1
adenylate cyclase
1
lysozyme
1
ACS
1
FPS
1
tyrosine hydroxylase
1
catalase
1
plasmin
1
phosphoinositide 3-kinase
1
complex I
1
topoisomerase
1
glutamate dehydrogenase
1
ribonucleotide reductase
1
P-glycoprotein
1
MAT
1
TdT
1
ribonucleotide reductase
1
glutamate dehydrogenase
1
topoisomerase
1
DNA methyltransferase
1
carboxypeptidase G2
1
thymidine kinase
1
Compound
Clin
379
calcium
349
Dec
225
phosphate
190
vitamin D
158
phosphorus
99
strontium
74
creatinine
54
sodium
48
aluminum
37
EHDP
33
His
30
nitrogen
27
Pamidronate
27
acetate
27
DNA
24
Vitamin D
19
Calcitonin
19
iron
19
retinoic acid
18
water
15
ALP
14
iodine
13
potassium
13
25-dihydroxycholecalciferol
13
TNF
12
oxygen
12
glutamate
12
glucose
11
CTX
10
Dial
10
Morphine
9
urea
9
carbonate
9
MDA
9
ATP
9
Adriamycin
9
A 42
8
Alendronate
8
phosphoric acid
7
fluorine
7
ICI
7
NH2
7
hydroxide
7
cAMP
6
Hemoglobin
6
Risedronate
6
Alendronate
6
Mithramycin
6
Androgen
6
Paclitaxel
5
sulfate
5
salt
5
5-FU
5
Optimal
5
BMD
5
HNO3
5
tin
5
1,4,7,10-tetraazacyclododecane
5
ADR
5
Voriconazole
5
Hydroxyurea
4
AMP
4
Aminoglutethimide
4
cysteine
4
L-PAM
4
lysine
4
DTPA
4
APAP
4
tyrosine
4
Estracyt
4
nitrate
4
Parenteral
4
ACTH
4
ethanol
4
zinc
4
cadmium
4
L-PAM
4
MTT
4
DIC
4
more...