Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0151825 (bone pain)
3,118 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
alkaline phosphatase 279
Sep 190
parathyroid hormone 141
She 103
calcitonin 87
granulocyte colony-stimulating factor 87
Mol 69
MRI 54
hemoglobin 53
CSF 47
granulocyte 45
G-CSF 42
PTH 39
prostate-specific antigen 39
RANKL 33
FDG 33
cytokine 32
osteocalcin 32
chronic renal failure 31
RANK 29
non-Hodgkin's lymphoma 28
Walker 26
granulocyte-macrophage colony-stimulating factor 26
osteoprotegerin 26
interferon 25
PSA 25
osteosarcoma 25
MDP 24
parathormone 24
type I collagen 24
glucocerebrosidase 23
acid phosphatase 23
imiglucerase 22
CD34 22
collagen 22
lactate dehydrogenase 20
Calcitonin 19
aromatase 18
parathyroid hormone-related protein 17
C-reactive protein 17
more...
Disease
cancer 824
tumor 454
bone metastases 422
metastases 383
multiple myeloma 330
hypercalcemia 326
bone disease 313
prostate cancer 289
breast cancer 278
osteoporosis 209
osteomalacia 207
carcinoma 167
anemia 160
PDB 136
hyperparathyroidism 120
spinal cord compression 118
thrombocytopenia 108
leukemia 97
pathological fracture 91
neutropenia 82
osteomyelitis 82
lymphoma 79
Gaucher disease 74
renal failure 71
pruritus 67
bone cancer 61
acute lymphoblastic leukemia 59
rash 56
rickets 56
lung cancer 53
primary hyperparathyroidism 52
lymphadenopathy 51
chronic pain 49
dysplasia 47
metastatic breast cancer 47
adenoma 46
tumor growth 43
arthritis 42
sickle cell disease 41
depression 41
more...
Symptom
bone pain 3118
pain 809
weakness 170
fatigue 131
headache 88
cancer pain 68
arthralgia 66
nausea 62
analgesia 50
myalgia 50
splenomegaly 49
diarrhea 47
back pain 43
vomiting 41
dyspnea 33
abdominal pain 33
hepatosplenomegaly 32
anorexia 25
hepatomegaly 23
collapse 21
flushing 20
Ill 20
constipation 18
nausea and vomiting 17
chest pain 15
discomfort 15
seizures 15
discomfort 15
insomnia 14
night sweats 14
low back pain 14
polyuria 14
asthenia 13
pallor 13
paresthesia 13
anesthesia 12
polydipsia 12
lethargy 12
cough 12
clubbing 12
more...
Drug
G-CSF 63
CSF 58
Zoledronic acid 52
Zoledronic acid 47
PTH 39
EHDP 38
Clodronate 24
APD 18
Filgrastim 18
Ibandronate 16
Dermatol 14
Filgrastim 13
Denosumab 13
Aredia 13
SrCl2 11
Dial 10
CTX 10
ascorbate 9
Zoladex 8
Zoladex 8
ICI 7
CTX 7
CTX 7
MRC 6
Leaf 6
Adriamycin 6
Gallium nitrate 5
Salmon calcitonin 5
Lenograstim 5
Adefovir dipivoxil 4
Cerezyme 4
Quadramet 4
PMPA 4
Ceredase 4
Cerezyme 4
Prednisone 3
VCR 3
IFN-gamma 3
Rituximab 3
Estracyt 3
more...
Enzyme
alkaline phosphatase 279
prostate-specific antigen 36
lactate dehydrogenase 25
MDP 24
ERK 24
mitogen-activated protein kinase 23
acid phosphatase 23
glucocerebrosidase 19
focal adhesion kinase 8
cathepsin K 8
proteasome 6
CD10 6
aspartate aminotransferase 5
prostate-specific membrane antigen 5
calcineurin 5
protein kinase 5
alanine aminotransferase 4
trypsin 4
creatine kinase 4
ATPase 4
MEK 3
CaMKII 3
protein kinase C 3
luciferase 3
peroxidase 3
elastase 2
beta-glucosidase 2
MIP 2
granzyme B 2
AST 2
HOA 2
tryptase 2
gamma-glutamyl transpeptidase 2
monoacylglycerol lipase 2
beta-glucosidase 2
BMT 2
ACS 1
urokinase-type plasminogen activator 1
topoisomerase 1
SMP 1
more...
Compound
Clin 379
calcium 349
Dec 225
phosphate 190
vitamin D 158
phosphorus 99
strontium 74
creatinine 54
sodium 48
aluminum 37
EHDP 33
His 30
Pamidronate 27
acetate 27
nitrogen 27
DNA 24
Calcitonin 19
iron 19
Vitamin D 19
retinoic acid 18
water 15
ALP 14
potassium 13
iodine 13
25-dihydroxycholecalciferol 13
glutamate 12
TNF 12
oxygen 12
glucose 11
Dial 10
CTX 10
Adriamycin 9
MDA 9
urea 9
carbonate 9
ATP 9
Morphine 9
A 42 8
Alendronate 8
ICI 7
more...