Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0151814 (coronary occlusion)
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Human Gene/Protein
mitogen-activated protein kinase-activated protein kinase 3 11.1
ring finger protein 182 10.8
alpha-1B adrenergic receptor 10.3
RP30 9.5
BCL2-associated agonist of cell death 9.4
prostaglandin reductase 2 9.3
Myx 9.1
V1-4 8.8
IP3K 8.4
TNG 8.4
LAD 8.1
Mel1a melatonin receptor 8.1
UCN2 7.9
BRAVO 7.9
HSPB2 7.8
mCANP 7.8
IGF1R protein 7.7
PDHC 7.7
ms2 7.5
plasma membrane monoamine transporter 7.5
CCTA 7.2
KIP2 7.2
kallikrein 7 7.1
cardiac myosin binding protein-C 7.1
CLS 7.1
SLC29A3 7.0
ADORA2B 6.9
A3 adenosine receptor 6.9
NPPA 6.9
SOLO 6.8
TET1 6.8
organic cation transporter 3 6.8
phospholipase inhibitor 6.8
HSP10 6.7
DSS1 6.6
Rnd3 6.6
UAP 6.6
CPK 6.5
cAMP response element-binding protein 1 6.5
IKCa1 6.5
SYS 6.5
MCG 6.5
ankyrin-G 6.4
GP130 6.4
Trif 6.4
adenosine A3 receptor 6.4
pancreatic stone protein 6.3
muscarinic M2 receptor 6.3
SCAD 6.3
AHAS 6.3
ITGB2 6.3
calcium-independent phospholipase A2 6.2
ENDO 6.2
MRX 6.2
AGL 6.2
AIP1 6.2
Mi-2 6.1
Tissue kallikrein 6.1
ENT2 6.1
LDC 6.1
TBX2 6.1
IGFI 6.0
Adenylyl cyclase 6.0
Kir2.2 5.9
calcium-activated neutral protease 5.9
FH1 5.9
N-acetyl-beta-glucosaminidase 5.9
platelet collagen receptor 5.9
Kir2.3 5.9
CBX3 5.9
endocan 5.9
HSPC 5.8
heat shock protein 72 5.8
Granulocyte-colony stimulating factor 5.7
Kir1.1 5.7
Cardiac troponin I 5.7
ecto-5'-nucleotidase 5.7
cTnT 5.7
MM1 5.6
creatine kinase 5.6
more...
Disease
coronary occlusion 13.1
Right coronary artery occlusion 11.8
Myocardial hemorrhage 11.1
RP30 10.8
Stunned myocardium 10.1
Acute myocardial ischemia 10.0
Non-Q wave myocardial infarction 9.8
potassium intoxication 9.8
Coronary restenosis 9.4
Subendocardial ischemia 9.4
Stable angina 9.0
Severe hypothyroidism 8.8
Myocardial necrosis 8.6
Brodie 8.3
coronary thrombosis 8.3
LAD 8.1
ventricular fibrillation 8.0
Left ventricular aneurysm 7.7
myocardial hypoxia 7.7
Acute renal insufficiency 7.7
coronary artery rupture 7.7
VED 7.4
myocardial ischemia 7.4
Q wave MI 7.3
Stress cardiomyopathy 7.2
acute myocardial infarction 7.0
Severe depression 7.0
Acute coronary syndrome 6.9
HMR 6.9
anterolateral myocardial infarction 6.9
unstable angina 6.8
myocardial infarction 6.7
ischemia 6.7
Takotsubo syndrome 6.6
chronic ischemic heart disease 6.5
coronary artery spasm 6.4
CLS 6.4
anterior myocardial infarction 6.3
Prinzmetal 6.3
inferior myocardial infarction 6.3
vasospastic angina 6.2
cardiosclerosis 6.1
akinesia 6.0
Hemodynamic instability 5.9
Transient ischemia 5.9
valvulitis 5.8
ventricular failure 5.8
myopericarditis 5.8
coronary insufficiency 5.8
VES 5.7
HEART 5.7
dyskinesia 5.7
Thrombus 5.7
anteroseptal myocardial infarction 5.6
renal hypertension 5.6
hyperviscosity syndrome 5.5
ventricular dilatation 5.5
Spontaneous pneumothorax 5.4
aortic valvular disease 5.4
Bezold 5.4
angioid streaks 5.3
MSF 5.3
STEMI 5.3
left ventricular failure 5.2
left bundle branch block 5.1
PIE 5.0
coronary artery disease 4.9
vascular obstruction 4.9
causalgia 4.9
Kimura's disease 4.8
anxiety state 4.7
Fibrillation 4.6
ventricular hypertrophy 4.6
MMA 4.6
chronic stable angina 4.5
Plaque 4.4
cerebrovascular insufficiency 4.4
hemopericardium 4.4
Acute Stroke 4.4
hypertensive heart disease 4.4
more...
Symptom
asynergy 7.5
Acute chest pain 7.5
precordial pain 6.6
peau d'orange 6.6
Decreased activity 6.3
cardiovascular impairment 6.3
bigeminal 6.1
angina 6.0
sinus pressure 6.0
spasm 5.6
chest pain 5.6
functional recovery 5.2
thinning 4.7
Excitability 4.7
belching 4.4
Anoxia 4.0
muscle stiffness 3.8
atypical chest pain 3.8
exertional angina 3.5
chest tightness 3.5
Stiffness 3.1
hypothermia 3.1
pallor 2.8
despair 2.4
oliguria 2.2
regurgitation 2.1
hopelessness 1.9
anesthesia 1.8
shortness of breath 1.7
hyperoxia 1.7
collapse 1.4
exertional dyspnea 1.3
cyanosis 1.2
dyspnea 1.1
discomfort 0.9
acute stress 0.9
discomfort 0.8
flushing 0.4
exhaustion 0.3
arthralgia 0.3
hypercapnia 0.1
pain -0.0
syncope -0.1
dizziness -0.2
insomnia -0.3
back pain -0.5
starvation -0.5
sleepiness -0.6
weakness -1.1
respiratory distress -1.2
nausea -1.4
fatigue -1.6
overweight -1.6
headache -1.7
analgesia -1.7
seizures -3.2
Drug
Sprodiamide 11.5
Pirsidomine 11.1
Esberiven 10.5
Bidisomide 10.1
Ifetroban 9.9
Carperitide 9.2
Arfonad 9.1
Piriprost 9.0
SUN 1165 8.7
Arfonad 8.6
Molsidomine 8.2
Aprindine 8.2
Ilomastat 7.8
Conivaptan 7.8
Dazmegrel 7.8
Voglibose 7.7
Cicletanine 7.7
Visken 7.7
Timolol 7.5
Nisoxetine 7.3
Abciximab 7.1
Rauwolfia serpentina 7.0
Pimobendan 6.9
CLS 6.9
Streptokinase 6.5
Ancrod 6.4
Phosphoramidon 6.3
TTC 6.3
nitroglycerin 6.3
Trapidil 6.2
Amrinone 6.2
Cyanoacrylate 5.7
Inderal 5.6
APM 5.6
Fenoldopam 5.5
Cilostazol 5.4
Atenolol 5.3
Poloxamer 188 5.3
Alteplase 5.3
Rosuvastatin 5.3
Argatroban 5.2
Ranolazine 5.1
Ranolazine 5.1
Iopamidol 5.1
Alteplase 5.1
Magnesium sulfate 5.1
Levovist 5.0
Alteplase 5.0
GHRP 4.9
Levosimendan 4.8
Premarin 4.8
Exenatide 4.8
Captopril 4.7
Optison 4.6
Felodipine 4.5
Tao 4.5
CTT 4.4
Aminoguanidine 4.3
Rolipram 4.3
Liraglutide 4.3
Adenosine triphosphate 4.3
Hyaluronidase 4.3
Methylprednisolone 4.2
ETA 4.2
Papaverine 4.2
Cardiovasc 4.2
Hyaluronidase 4.1
TAK 4.1
Iloprost 4.0
Urokinase 3.8
Ouabain 3.8
Glide 3.8
Lovastatin 3.7
DMSA 3.5
ICI 3.5
MgSO4 3.5
Bupivacaine 3.5
Indomethacin 3.4
Pravastatin 3.4
PTC 3.3
more...
Enzyme
LMT 7.3
creatine kinase 5.8
CAO 5.6
KLK7 5.6
kynureninase 5.5
3-mercaptopyruvate sulfurtransferase 5.2
SPT 5.0
SPT 4.8
endothelin-converting enzyme 4.8
CPN 4.3
lactic acid dehydrogenase 4.2
AMP-activated kinase 4.2
lactic acid dehydrogenase 4.2
Hageman factor 4.1
tissue plasminogen activator 4.1
cystathionine gamma-lyase 4.0
urokinase-type plasminogen activator 3.9
1-hydroxylase 3.9
succinic dehydrogenase 3.9
tissue kallikrein 3.8
hyaluronidase 3.7
CAD 3.6
CAD 3.6
NO synthase 3.5
CAD 3.5
lactic acid dehydrogenase 3.5
acyl-CoA dehydrogenase 3.5
CFI 3.5
NOS 3.4
m-calpain 3.4
xanthine oxidase 3.4
adenosine deaminase 3.3
GRK2 3.3
adenosine deaminase 3.3
aconitase 3.3
hyaluronidase 3.3
caspase-7 3.3
BMA 3.3
Pla 3.3
caspase-7 3.2
Rex 3.2
phosphorylase 3.2
lactate dehydrogenase 3.2
superoxide dismutase 3.2
nucleotidase 3.1
lysin 3.1
alpha-glucosidase 3.0
ACE 3.0
PDK1 2.9
3-hydroxy-3-methylglutaryl-CoA reductase 2.9
myosin ATPase 2.9
xanthine dehydrogenase 2.8
lipoxygenase 2.8
alpha-ketoglutarate dehydrogenase 2.8
phosphofructokinase 2.8
chymase 2.7
succinate dehydrogenase 2.7
acyl-CoA dehydrogenase 2.6
phosphoinositide 3-kinase 2.6
plasmin 2.5
beta-glucuronidase 2.5
protein kinase C 2.5
caspase-3 2.5
AMPK 2.5
5'-nucleotidase 2.4
dipeptidyl peptidase IV 2.4
phosphodiesterase 2.3
caspase-8 2.3
pyruvate dehydrogenase 2.3
pyruvate dehydrogenase 2.3
prostaglandin synthetase 2.2
PDE 2.2
TdT 2.2
catalase 2.2
kallikrein 2.1
MMP 2.0
guanylate cyclase 2.0
NADH dehydrogenase 2.0
peroxidase 2.0
glutathione peroxidase 2.0
more...
Compound
1,1-diphenyl-1-butanol 12.1
Corynanthine 9.8
Teprotide 9.4
Iprindole 8.9
Miglitol 8.2
N-hydroxyguanidine 8.0
6-Keto-PGF1a 8.0
Bretylium 8.0
Gallopamil 7.9
Metipranolol 7.9
Adrenochrome 7.8
Sulfinpyrazone 7.8
Nicorandil 7.6
Tiapamil 7.6
Timolol 7.5
Nitroglycerin 7.5
Encainide 7.5
Clofilium 7.5
Sparteine 7.3
hexanamide 7.3
14,15-DHET 7.3
DDMS 7.3
Monastral Blue 7.2
Sodium hydrosulfide 7.2
Cromakalim 7.2
F6P 7.1
EXP 3174 7.1
F6P 7.1
Dofetilide 7.1
CLS 7.0
Quinapril 7.0
Diltiazem 7.0
Diltiazem 7.0
Atractyloside 6.9
Practolol 6.8
Hearts 6.8
Nalmefene 6.7
Azan 6.7
4-methoxybenzaldehyde 6.7
4-methoxybenzaldehyde 6.7
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
Glibenclamide 6.5
4-methoxybenzaldehyde 6.5
Xamoterol 6.5
4-methoxybenzaldehyde 6.4
Bepridil 6.4
TTC 6.4
4-methoxybenzaldehyde 6.3
Phosphoramidon 6.3
SD 25 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Fludrocortisone 6.2
IPC 6.2
Betaxolol 6.2
Aconitine 6.2
Aconitine 6.2
Methoxamine 6.1
CoQ9 6.1
Pinacidil 6.0
DETA 6.0
Nifedipine 5.9
Isoflurane 5.9
Hearts 5.9
Glimepiride 5.9
PGG2 5.9
Enflurane 5.8
Nicardipine 5.8
Malonate 5.8
Dobutamine 5.8
Propranolol 5.8
Propranolol 5.8
Meclofenamate 5.8
Ajmaline 5.7
Verapamil 5.7
more...