Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0151814 (coronary occlusion)
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Human Gene/Protein
mitogen-activated protein kinase-activated protein kinase 3 11.1
ring finger protein 182 10.8
alpha-1B adrenergic receptor 10.3
RP30 9.5
BCL2-associated agonist of cell death 9.4
prostaglandin reductase 2 9.3
Myx 9.1
V1-4 8.8
IP3K 8.4
TNG 8.4
LAD 8.1
Mel1a melatonin receptor 8.1
UCN2 7.9
BRAVO 7.9
HSPB2 7.8
mCANP 7.8
IGF1R protein 7.7
PDHC 7.7
ms2 7.5
plasma membrane monoamine transporter 7.5
CCTA 7.2
KIP2 7.2
kallikrein 7 7.1
cardiac myosin binding protein-C 7.1
CLS 7.1
SLC29A3 7.0
ADORA2B 6.9
A3 adenosine receptor 6.9
NPPA 6.9
SOLO 6.8
TET1 6.8
organic cation transporter 3 6.8
phospholipase inhibitor 6.8
HSP10 6.7
DSS1 6.6
Rnd3 6.6
UAP 6.6
CPK 6.5
cAMP response element-binding protein 1 6.5
IKCa1 6.5
SYS 6.5
MCG 6.5
GP130 6.4
ankyrin-G 6.4
Trif 6.4
adenosine A3 receptor 6.4
pancreatic stone protein 6.3
muscarinic M2 receptor 6.3
AHAS 6.3
SCAD 6.3
ITGB2 6.3
calcium-independent phospholipase A2 6.2
ENDO 6.2
MRX 6.2
AGL 6.2
AIP1 6.2
Mi-2 6.1
Tissue kallikrein 6.1
ENT2 6.1
LDC 6.1
TBX2 6.1
IGFI 6.0
Adenylyl cyclase 6.0
Kir2.2 5.9
calcium-activated neutral protease 5.9
FH1 5.9
N-acetyl-beta-glucosaminidase 5.9
platelet collagen receptor 5.9
Kir2.3 5.9
CBX3 5.9
endocan 5.9
HSPC 5.8
heat shock protein 72 5.8
Granulocyte-colony stimulating factor 5.7
Cardiac troponin I 5.7
Kir1.1 5.7
ecto-5'-nucleotidase 5.7
cTnT 5.7
MM1 5.6
creatine kinase 5.6
PTG 5.6
potassium ion channel 5.6
macrophage derived 5.6
BR1 5.6
ENT1 5.6
PFB 5.6
protein kinase C epsilon 5.5
kynureninase 5.5
HSP72 5.5
Fas-associated death domain protein 5.5
carboxypeptidase N 5.5
adenosine receptor 5.4
TSG 5.4
cyclin E2 5.4
Aldose reductase 5.3
DCI 5.3
MSF 5.3
CPT II 5.3
PEDF 5.2
brain-heart 5.2
EDD 5.2
ESP 5.2
CPI-17 5.2
RIP3 5.2
RAO 5.2
RR1 5.2
lactic acid dehydrogenase 5.1
Nix 5.1
TFEB 5.1
MAC-1 5.1
KLF5 5.1
Creatine kinase 5.1
DAO 5.1
Angiotensin II receptor 5.1
ABCC6 5.1
MM2 5.1
HSC70 5.1
APJ 5.1
Myeloperoxidase 5.1
alpha-tocopherol transfer protein 5.0
SPT 5.0
apelin receptor 5.0
nucleotide-binding protein 5.0
mPGES-1 5.0
CSF1 5.0
mitochondrial aconitase 5.0
neutrophil-activating peptide-2 5.0
Nav1.5 5.0
adenosine A1 receptor 5.0
beta-adrenergic receptor kinase 5.0
Factor XII 5.0
glycoprotein IIIa 5.0
apelin 4.9
DRP1 4.9
catechol O-methyltransferase 4.9
alpha-fodrin 4.9
PED 4.9
Kir2.1 4.9
cardiac troponin I 4.9
HSP40 4.9
PIM1 4.9
cardiotrophin-1 4.9
CVT 4.9
CAO 4.9
ET-2 4.9
PDK4 4.8
NRF1 4.8
EDL 4.8
MLKL 4.8
HL-1 4.8
DOB 4.8
CSF1R 4.8
classical) 4.8
STAT5B 4.8
VEGF-B 4.8
NCM 4.7
Na+/Ca2+ exchanger 4.7
PI3-kinase 4.7
gamma, delta 4.7
Cor 4.7
more...
Disease
coronary occlusion 13.1
Right coronary artery occlusion 11.8
Myocardial hemorrhage 11.1
RP30 10.8
Stunned myocardium 10.1
Acute myocardial ischemia 10.0
Non-Q wave myocardial infarction 9.8
potassium intoxication 9.8
Subendocardial ischemia 9.4
Coronary restenosis 9.4
Stable angina 9.0
Severe hypothyroidism 8.8
Myocardial necrosis 8.6
Brodie 8.3
coronary thrombosis 8.3
LAD 8.1
ventricular fibrillation 8.0
Left ventricular aneurysm 7.7
myocardial hypoxia 7.7
coronary artery rupture 7.7
Acute renal insufficiency 7.7
VED 7.4
myocardial ischemia 7.4
Q wave MI 7.3
Stress cardiomyopathy 7.2
acute myocardial infarction 7.0
Severe depression 7.0
Acute coronary syndrome 6.9
anterolateral myocardial infarction 6.9
HMR 6.9
unstable angina 6.8
myocardial infarction 6.7
ischemia 6.7
Takotsubo syndrome 6.6
chronic ischemic heart disease 6.5
coronary artery spasm 6.4
CLS 6.4
anterior myocardial infarction 6.3
Prinzmetal 6.3
inferior myocardial infarction 6.3
vasospastic angina 6.2
cardiosclerosis 6.1
akinesia 6.0
Hemodynamic instability 5.9
Transient ischemia 5.9
valvulitis 5.8
ventricular failure 5.8
myopericarditis 5.8
coronary insufficiency 5.8
VES 5.7
HEART 5.7
dyskinesia 5.7
Thrombus 5.7
anteroseptal myocardial infarction 5.6
renal hypertension 5.6
hyperviscosity syndrome 5.5
ventricular dilatation 5.5
Spontaneous pneumothorax 5.4
aortic valvular disease 5.4
Bezold 5.4
angioid streaks 5.3
MSF 5.3
STEMI 5.3
left ventricular failure 5.2
left bundle branch block 5.1
PIE 5.0
coronary artery disease 4.9
vascular obstruction 4.9
causalgia 4.9
Kimura's disease 4.8
anxiety state 4.7
Fibrillation 4.6
ventricular hypertrophy 4.6
MMA 4.6
chronic stable angina 4.5
Plaque 4.4
cerebrovascular insufficiency 4.4
hemopericardium 4.4
Acute Stroke 4.4
hypertensive heart disease 4.4
Kawasaki disease 4.4
ASAT 4.3
idiopathic cardiomyopathy 4.2
atrioventricular block 4.2
chondromalacia 4.2
HSP 4.1
bradyarrhythmia 4.1
NAME 4.0
ischemic cardiomyopathy 4.0
epicondylitis 4.0
Zinc deficiency 3.9
sympathomimetic 3.9
Bradley 3.8
right bundle branch block 3.8
SEM 3.8
aortic stenosis 3.8
heart block 3.8
Evans 3.8
Wolff-Parkinson-White syndrome 3.7
tension pneumothorax 3.7
Tic 3.6
valvular heart disease 3.6
EMD 3.6
right heart failure 3.5
idiopathic thrombocytopenic purpura 3.5
coronary heart disease 3.5
syndrome X 3.5
MAC 3.5
plaque 3.5
pseudoxanthoma elasticum 3.5
IPS 3.5
torsades de pointes 3.5
aortic regurgitation 3.5
heart failure 3.4
AMN 3.4
cardiomyopathy 3.4
MSA 3.4
mitral regurgitation 3.4
NPH 3.3
congestive heart failure 3.3
pulmonic stenosis 3.3
fat embolism 3.3
magnesium deficiency 3.3
calcinosis 3.3
PSP 3.3
AGA 3.3
Familial hypercholesterolemia 3.2
acute myocarditis 3.2
malignant hypertension 3.1
hypochondriasis 3.1
pericarditis 3.1
EPI 3.0
LDLR 3.0
Wiskott-Aldrich syndrome 3.0
arteriosclerosis 2.9
vitreous humor 2.9
bicuspid 2.9
reflex sympathetic dystrophy 2.9
rheumatic heart disease 2.9
Takayasu 2.9
adrenal mass 2.9
sick sinus syndrome 2.9
atherosclerosis 2.9
thrombophlebitis 2.8
thiamine deficiency 2.8
erythrocytosis 2.8
essential thrombocythemia 2.8
drug hypersensitivity 2.8
hypercholesterolemia 2.8
PDE 2.8
flutter 2.7
depression 2.7
coccidioidomycosis 2.6
emotional stress 2.6
myocarditis 2.6
peripheral vascular disease 2.6
Tension 2.5
Brugada syndrome 2.5
nephrosis 2.5
stuttering 2.5
more...
Symptom
asynergy 7.5
Acute chest pain 7.5
precordial pain 6.6
peau d'orange 6.6
Decreased activity 6.3
cardiovascular impairment 6.3
bigeminal 6.1
angina 6.0
sinus pressure 6.0
spasm 5.6
chest pain 5.6
functional recovery 5.2
thinning 4.7
Excitability 4.7
belching 4.4
Anoxia 4.0
muscle stiffness 3.8
atypical chest pain 3.8
exertional angina 3.5
chest tightness 3.5
Stiffness 3.1
hypothermia 3.1
pallor 2.8
despair 2.4
oliguria 2.2
regurgitation 2.1
hopelessness 1.9
anesthesia 1.8
shortness of breath 1.7
hyperoxia 1.7
collapse 1.4
exertional dyspnea 1.3
cyanosis 1.2
dyspnea 1.1
discomfort 0.9
acute stress 0.9
discomfort 0.8
flushing 0.4
exhaustion 0.3
arthralgia 0.3
hypercapnia 0.1
pain -0.0
syncope -0.1
dizziness -0.2
insomnia -0.3
back pain -0.5
starvation -0.5
sleepiness -0.6
weakness -1.1
respiratory distress -1.2
nausea -1.4
fatigue -1.6
overweight -1.6
headache -1.7
analgesia -1.7
seizures -3.2
Drug
Sprodiamide 11.5
Pirsidomine 11.1
Esberiven 10.5
Bidisomide 10.1
Ifetroban 9.9
Carperitide 9.2
Arfonad 9.1
Piriprost 9.0
SUN 1165 8.7
Arfonad 8.6
Molsidomine 8.2
Aprindine 8.2
Ilomastat 7.8
Dazmegrel 7.8
Conivaptan 7.8
Cicletanine 7.7
Voglibose 7.7
Visken 7.7
Timolol 7.5
Nisoxetine 7.3
Abciximab 7.1
Rauwolfia serpentina 7.0
Pimobendan 6.9
CLS 6.9
Streptokinase 6.5
Ancrod 6.4
Phosphoramidon 6.3
TTC 6.3
nitroglycerin 6.3
Trapidil 6.2
Amrinone 6.2
Cyanoacrylate 5.7
Inderal 5.6
APM 5.6
Fenoldopam 5.5
Cilostazol 5.4
Atenolol 5.3
Poloxamer 188 5.3
Alteplase 5.3
Rosuvastatin 5.3
Argatroban 5.2
Ranolazine 5.1
Ranolazine 5.1
Iopamidol 5.1
Alteplase 5.1
Magnesium sulfate 5.1
Levovist 5.0
Alteplase 5.0
GHRP 4.9
Levosimendan 4.8
Premarin 4.8
Exenatide 4.8
Captopril 4.7
Optison 4.6
Felodipine 4.5
Tao 4.5
CTT 4.4
Aminoguanidine 4.3
Rolipram 4.3
Liraglutide 4.3
Adenosine triphosphate 4.3
Hyaluronidase 4.3
Methylprednisolone 4.2
ETA 4.2
Papaverine 4.2
Cardiovasc 4.2
Hyaluronidase 4.1
TAK 4.1
Iloprost 4.0
Urokinase 3.8
Ouabain 3.8
Glide 3.8
Lovastatin 3.7
DMSA 3.5
ICI 3.5
MgSO4 3.5
Bupivacaine 3.5
Indomethacin 3.4
Pravastatin 3.4
PTC 3.3
Aprotinin 3.2
Ringer's solution 3.2
Sodium nitroprusside 3.1
PFA 3.1
EPI 3.0
FLP 3.0
Clopidogrel 3.0
Phentolamine 2.9
CEC 2.9
Pronase 2.7
Vitamin K 2.6
NADH 2.6
Cimetidine 2.4
Atropine 2.4
Simvastatin 2.4
Cimetidine 2.4
Angiotensin II 2.3
Glutathione 2.3
Fructose 2.2
Theophylline 2.1
uPA 2.0
Propofol 2.0
NAG 2.0
ACT 2.0
Nitric Oxide 1.7
Histamine 1.6
Growth hormone 1.5
Growth hormone 1.5
ROS 1.4
Vitamin E 1.4
vitamin E 1.3
ROC 1.2
p75 1.2
EE2 1.1
Portal 1.0
ascorbate 0.9
MAP 0.7
G-CSF 0.7
Bifidobacterium 0.6
Nephron 0.5
PTH 0.3
Biopolymers 0.0
ENT 0.0
Monit -0.0
Ethanol -0.2
citric acid -0.2
caffeine -0.3
Gel -0.8
lactose -1.0
lysine -1.2
Dial -1.8
Enzyme
LMT 7.3
creatine kinase 5.8
CAO 5.6
KLK7 5.6
kynureninase 5.5
3-mercaptopyruvate sulfurtransferase 5.2
SPT 5.0
SPT 4.8
endothelin-converting enzyme 4.8
CPN 4.3
lactic acid dehydrogenase 4.2
AMP-activated kinase 4.2
lactic acid dehydrogenase 4.2
Hageman factor 4.1
tissue plasminogen activator 4.1
cystathionine gamma-lyase 4.0
urokinase-type plasminogen activator 3.9
1-hydroxylase 3.9
succinic dehydrogenase 3.9
tissue kallikrein 3.8
hyaluronidase 3.7
CAD 3.6
CAD 3.6
NO synthase 3.5
CAD 3.5
lactic acid dehydrogenase 3.5
acyl-CoA dehydrogenase 3.5
CFI 3.5
NOS 3.4
m-calpain 3.4
xanthine oxidase 3.4
adenosine deaminase 3.3
GRK2 3.3
adenosine deaminase 3.3
aconitase 3.3
hyaluronidase 3.3
caspase-7 3.3
BMA 3.3
Pla 3.3
caspase-7 3.2
Rex 3.2
phosphorylase 3.2
lactate dehydrogenase 3.2
superoxide dismutase 3.2
nucleotidase 3.1
lysin 3.1
alpha-glucosidase 3.0
ACE 3.0
PDK1 2.9
3-hydroxy-3-methylglutaryl-CoA reductase 2.9
myosin ATPase 2.9
xanthine dehydrogenase 2.8
lipoxygenase 2.8
alpha-ketoglutarate dehydrogenase 2.8
phosphofructokinase 2.8
chymase 2.7
succinate dehydrogenase 2.7
acyl-CoA dehydrogenase 2.6
phosphoinositide 3-kinase 2.6
plasmin 2.5
beta-glucuronidase 2.5
protein kinase C 2.5
caspase-3 2.5
AMPK 2.5
5'-nucleotidase 2.4
dipeptidyl peptidase IV 2.4
phosphodiesterase 2.3
caspase-8 2.3
pyruvate dehydrogenase 2.3
pyruvate dehydrogenase 2.3
prostaglandin synthetase 2.2
PDE 2.2
TdT 2.2
catalase 2.2
kallikrein 2.1
MMP 2.0
guanylate cyclase 2.0
NADH dehydrogenase 2.0
peroxidase 2.0
glutathione peroxidase 2.0
cytochrome oxidase 2.0
phosphatidylinositol 3-kinase 2.0
thrombin 2.0
soluble epoxide hydrolase 2.0
GSK 1.9
renin 1.9
diamine oxidase 1.8
MAP 1.8
PKG 1.8
hexokinase 1.7
peroxiredoxin 1.7
monoamine oxidase 1.7
pyruvate dehydrogenase 1.7
NADPH oxidase 1.6
complex I 1.5
isocitrate dehydrogenase 1.5
AMPK 1.5
CD10 1.4
AMP-activated protein kinase 1.4
ATPase 1.4
granzyme B 1.4
aldose reductase 1.4
PARP 1.3
isocitrate dehydrogenase 1.3
beta-galactosidase 1.2
collagenase 1.2
citrate synthase 0.9
MEK 0.9
CPT 0.9
malate dehydrogenase 0.9
mitogen-activated protein kinase 0.9
adenylate cyclase 0.8
IKK 0.8
ceruloplasmin 0.8
deaminase 0.8
NADPH oxidase 0.7
aspartate aminotransferase 0.7
diaphorase 0.5
AST 0.5
caspase-1 0.5
choline acetyltransferase 0.5
acid phosphatase 0.4
thromboplastin 0.4
ATP synthase 0.3
phospholipase A2 0.3
protein kinase 0.2
caspase-9 0.2
luciferase 0.2
RNase 0.1
pepsin 0.0
RNase -0.1
gamma-glutamyl transpeptidase -0.1
transcriptase -0.1
glutathione reductase -0.1
ERK -0.1
proteasome -0.7
focal adhesion kinase -0.8
reverse transcriptase -0.9
alkaline phosphatase -0.9
APC -0.9
calcineurin -1.0
phospholipase C -1.1
ACS -1.2
alanine aminotransferase -1.6
RNA polymerase -2.0
trypsin -2.3
Compound
1,1-diphenyl-1-butanol 12.1
Corynanthine 9.8
Teprotide 9.4
Iprindole 8.9
Miglitol 8.2
N-hydroxyguanidine 8.0
6-Keto-PGF1a 8.0
Bretylium 8.0
Gallopamil 7.9
Metipranolol 7.9
Adrenochrome 7.8
Sulfinpyrazone 7.8
Nicorandil 7.6
Tiapamil 7.6
Timolol 7.5
Nitroglycerin 7.5
Encainide 7.5
Clofilium 7.5
Sparteine 7.3
hexanamide 7.3
14,15-DHET 7.3
DDMS 7.3
Monastral Blue 7.2
Sodium hydrosulfide 7.2
Cromakalim 7.2
F6P 7.1
F6P 7.1
EXP 3174 7.1
Dofetilide 7.1
CLS 7.0
Quinapril 7.0
Diltiazem 7.0
Diltiazem 7.0
Atractyloside 6.9
Practolol 6.8
Hearts 6.8
Nalmefene 6.7
Azan 6.7
4-methoxybenzaldehyde 6.7
4-methoxybenzaldehyde 6.7
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
4-methoxybenzaldehyde 6.6
Glibenclamide 6.5
4-methoxybenzaldehyde 6.5
Xamoterol 6.5
4-methoxybenzaldehyde 6.4
Bepridil 6.4
TTC 6.4
4-methoxybenzaldehyde 6.3
Phosphoramidon 6.3
SD 25 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Dipyridamole 6.3
Fludrocortisone 6.2
IPC 6.2
Betaxolol 6.2
Aconitine 6.2
Aconitine 6.2
Methoxamine 6.1
CoQ9 6.1
Pinacidil 6.0
DETA 6.0
Nifedipine 5.9
Isoflurane 5.9
Hearts 5.9
Glimepiride 5.9
PGG2 5.9
Enflurane 5.8
Nicardipine 5.8
Malonate 5.8
Dobutamine 5.8
Propranolol 5.8
Propranolol 5.8
Meclofenamate 5.8
Ajmaline 5.7
Verapamil 5.7
IPC 5.7
Verapamil 5.6
Mibefradil 5.6
4-OHT 5.6
Fenoldopam 5.6
Desipramine 5.6
Ticlopidine 5.6
Esmolol 5.5
DHBA 5.5
phosphocreatine 5.5
MCE 5.5
Candesartan 5.5
Pargyline 5.4
Sotalol 5.4
Lidocaine 5.4
Amlodipine 5.3
Farnesol 5.3
11,12-EET 5.3
prostaglandin F1 5.3
Deoxycoformycin 5.3
Selectin 5.3
Argatroban 5.3
Chelerythrine 5.3
Chelerythrine 5.3
DCI 5.3
TIF 5.2
heptadecanoic acid 5.2
methanesulfonamide 5.2
methanesulfonamide 5.1
heptadecanoic acid 5.1
Nisoldipine 5.1
Disopyramide 5.1
1H-indazole 5.1
SEE 5.1
Ergot 5.1
Capecitabine 5.0
TXA2 5.0
PGH2 5.0
Pentobarbital 5.0
Thromboxane B2 5.0
Magnesium sulfate 5.0
Cyanogen bromide 5.0
Procainamide 4.9
Evans Blue 4.9
Droperidol 4.9
Magnesium sulfate 4.8
Mexiletine 4.8
Apocynin 4.8
Premarin 4.8
DDA 4.8
rubidium 4.8
Edaravone 4.8
Etomidate 4.7
Fluvastatin 4.7
DDA 4.7
20-HETE 4.7
DDA 4.7
Cardiol 4.7
Adenosine 4.7
prostacyclin 4.6
Dichloroacetate 4.6
quinuclidine 4.6
quinuclidine 4.6
MMA 4.6
Tiron 4.6
Prazosin 4.6
Nitroprusside 4.6
TFC 4.6
Quinidine 4.5
2,3-dimercaptosuccinic acid 4.5
Metoprolol 4.5
BaCl2 4.5
PCI 4.5
ISDN 4.5
Labetalol 4.5
Pioglitazone 4.4
Metoprolol 4.4
2,3-dimercaptosuccinic acid 4.4
Methylprednisolone 4.4
FFA 4.3
more...