Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0151744 (
myocardial ischemia
)
31,282
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
2021
Mol
905
insulin
710
ATP
619
creatine kinase
555
lactate dehydrogenase
397
caspase-3
345
superoxide dismutase
339
HDL
323
fibrinogen
295
calcium channel
280
Bcl-2
271
renin
268
collagen
238
TNF
221
cytokine
216
tumor necrosis factor
208
Pol
206
C-reactive protein
195
albumin
191
vascular endothelial growth factor
182
ACE
178
nitric oxide synthase
178
angiotensin II
173
myeloperoxidase
168
hemoglobin
166
IL-6
163
bradykinin
163
Mal
162
thrombin
159
natriuretic peptide
158
PI3K
154
She
149
catalase
144
ADP
144
cardiac muscle
140
LAD
136
LDH
134
ATPase
128
MRI
128
Cor
118
p38
115
endothelin-1
111
troponin I
110
GSH
107
chronic renal failure
105
ERK1
103
endothelial nitric oxide synthase
101
CAD
96
glutathione peroxidase
95
ROS
94
SOD
94
cardiac troponin I
92
vascular endothelium
92
inducible nitric oxide synthase
91
Men
90
endoplasmic reticulum
89
eNOS
88
troponin T
88
MAPK
85
phosphodiesterase
82
interleukin-6
82
VEGF
80
beta 1
79
mTOR
77
cytochrome c
77
xanthine oxidase
76
Ang II
76
von Willebrand factor
75
AMP-activated protein kinase
74
myoglobin
74
PLA
72
AKT
71
JNK
71
NMR
71
NADH
70
TNF-alpha
69
AMP
69
Lp(a)
68
ERK
68
erythropoietin
67
cyclooxygenase
67
cardiac troponin T
66
factor VII
65
LDL receptor
63
CO2
63
p53
62
glycoprotein
61
P-selectin
61
AMPK
60
apolipoprotein
60
IL-10
60
serum albumin
59
TLR4
58
Gen
58
ICD
58
aspartate aminotransferase
57
COPD
56
CPK
55
atrial natriuretic peptide
54
CHD
54
reserved
54
BNP
54
prothrombin
54
heme oxygenase-1
51
PKC
50
NAD
50
apolipoprotein B
50
adiponectin
50
plasminogen activator inhibitor-1
49
CRP
48
adenosine receptor
48
IL-8
47
STAT3
47
intercellular adhesion molecule-1
47
protein kinase B
46
angiotensin receptor
46
Angiotensin-converting enzyme
45
ACS
45
kit
45
angiotensin II receptor
45
caspase-9
45
p65
44
Nrf2
44
myosin
43
A-I
42
GPIIb
42
phosphatidylinositol 3-kinase
42
RCM
41
GSK
41
tissue plasminogen activator
41
beta-endorphin
41
PARP
41
phospholipase A2
40
AT1
39
ASA
39
tyrosine kinase
39
opioid receptor
39
heat shock protein
39
HDL2
38
matrix metalloproteinase
38
glucagon
38
LC3
37
proteasome
37
ubiquitin
37
adhesion molecule
37
Endothelin-1
36
PCI
36
antithrombin III
36
HO-1
36
polypeptide
36
plasminogen activator inhibitor
35
peroxisome proliferator-activated receptor
35
vasopressin
35
reductase
34
cTnT
34
ET-1
34
lipopolysaccharide
34
chemokine
34
adenylyl cyclase
34
more...
Disease
myocardial ischemia
31282
ischemia
6238
myocardial infarction
4648
hypertension
3519
coronary artery disease
3124
heart failure
2676
diabetes
2483
stroke
2043
atherosclerosis
1852
acute myocardial infarction
1807
cardiovascular disease
1698
depression
1438
heart disease
1099
congestive heart failure
882
coronary heart disease
767
cancer
747
cardiomyopathy
716
obesity
689
unstable angina
687
ventricular fibrillation
667
coronary occlusion
608
ventricular hypertrophy
510
plaque
483
hypercholesterolemia
442
type 2 diabetes
375
dilated cardiomyopathy
371
hyperlipidemia
345
chronic obstructive pulmonary disease
327
renal disease
300
hypertrophic cardiomyopathy
293
peripheral vascular disease
259
vascular disease
258
lung cancer
250
dyslipidemia
245
valvular heart disease
233
cold
221
mitral regurgitation
218
anemia
206
tumor
205
myocarditis
205
coronary artery spasm
199
metabolic syndrome
197
asthma
197
chronic ischemic heart disease
196
pulmonary hypertension
192
renal failure
192
essential hypertension
171
aortic stenosis
162
chronic renal failure
157
hyperglycemia
154
pneumonia
150
sepsis
147
sepsis
142
LAD
136
SEM
135
Kawasaki disease
133
arteriosclerosis
133
vasospastic angina
131
chronic stable angina
129
retinopathy
122
psychological stress
122
hypertensive heart disease
118
pulmonary embolism
118
ischemic cardiomyopathy
112
pulmonary edema
112
cirrhosis
111
atrioventricular block
111
left ventricular failure
110
cerebral ischemia
109
coronary thrombosis
108
pericarditis
108
GSH
107
coronary insufficiency
103
breast cancer
103
osteoporosis
101
cerebral infarction
100
syndrome X
98
left bundle branch block
92
rheumatoid arthritis
91
obstructive sleep apnea
91
endocarditis
90
dementia
89
rheumatic heart disease
87
glucose intolerance
87
erectile dysfunction
84
diabetic cardiomyopathy
84
NAME
83
aortic regurgitation
81
hypothyroidism
80
idiopathic dilated cardiomyopathy
80
suicide
77
abdominal aortic aneurysm
77
transient ischemic attack
76
chronic disease
75
Alzheimer's disease
74
vasculitis
74
vaccinia
73
proteinuria
72
diabetic nephropathy
72
infectious diseases
72
sleep apnea
71
brucellosis
71
West
70
hyperinsulinemia
70
hyperlipoproteinemia
70
systemic lupus erythematosus
68
migraine
68
type 1 diabetes
67
neuropathy
67
flutter
66
autonomic neuropathy
65
anterior myocardial infarction
64
tuberculosis
64
ventricular dilatation
64
aortic aneurysm
63
cardiosclerosis
62
subarachnoid hemorrhage
61
mitral stenosis
61
mitral valve prolapse
61
respiratory disease
61
arthritis
60
Parkinson's disease
58
ICD
58
hypoglycemia
58
sympathomimetic
57
malnutrition
57
peptic ulcer
56
COPD
56
intermittent claudication
55
supraventricular tachycardia
54
microalbuminuria
54
aggression
54
HIV
54
respiratory failure
53
right bundle branch block
52
dysplasia
52
liver disease
52
hyperhomocysteinemia
52
idiopathic thrombocytopenic purpura
51
lung disease
50
carcinoma
50
Evans
50
cor pulmonale
49
Endothelial dysfunction
48
renal insufficiency
47
dyskinesia
47
heart block
47
thrombocytopenia
47
hyperthyroidism
47
atherosclerotic cardiovascular disease
46
bronchitis
45
cardiovascular risk factor
45
ATM
45
bronchitis
45
AIDS
44
influenza
44
osteoarthritis
44
emphysema
43
pericardial effusion
43
emotional stress
42
more...
Symptom
angina
2980
chest pain
1197
pain
634
anesthesia
562
spasm
382
dyspnea
219
functional recovery
214
syncope
158
exertional angina
140
overweight
138
hypothermia
128
headache
113
fatigue
111
discomfort
95
discomfort
95
asynergy
71
regurgitation
67
analgesia
67
dizziness
64
collapse
63
weakness
58
atypical chest pain
55
thinning
52
seizures
52
shortness of breath
51
cough
43
nausea
42
exhaustion
37
vomiting
36
respiratory distress
35
snoring
34
abdominal pain
34
sleepiness
31
exertional dyspnea
29
diarrhea
29
hypercapnia
28
flushing
24
starvation
21
nausea and vomiting
19
precordial pain
19
exertional chest pain
18
cyanosis
17
dystonia
16
vertigo
15
back pain
14
insomnia
14
acute stress
13
constipation
13
anorexia
12
myalgia
12
hemoptysis
12
presyncope
11
ataxia
10
tachypnea
10
syncopal episodes
10
epigastric pain
10
low back pain
10
acidity
10
cachexia
10
asthenia
10
Ill
10
cardialgia
9
arthralgia
9
lethargy
9
paresthesia
9
hemiplegia
9
sinus pressure
8
CSR
8
chest tightness
8
agitation
8
Anoxia
8
pallor
8
hyperoxia
8
tremor
7
erythema
7
rales
7
oliguria
7
neck pain
7
tingling
7
hepatomegaly
7
wheezing
6
ECG signs of myocardial ischemia
6
shoulder pain
6
productive cough
5
livedo
5
dysuria
5
menopausal symptoms
5
Multimorbidity
5
hypertonia
5
hopelessness
5
Decreased activity
5
paresis
5
alexithymia
5
acute pain
5
tinnitus
4
leg pain
4
jaw pain
4
orthopnea
4
colic
4
flank pain
4
Refractory angina pectoris
4
Cardiac pain
4
lightheadedness
4
cardiovascular impairment
4
giddiness
4
giddiness
4
arm pain
3
blurred vision
3
hot flashes
3
dysarthria
3
bone pain
3
hypocapnia
3
Sedation
3
hot flushes
3
acute abdominal pain
3
apathy
3
chorea
3
muscle stiffness
3
HSA
3
consciousness disturbance
3
stigma
3
night sweats
3
numbness
3
chronic constipation
3
bigeminal
3
Postoperative pain
3
heartburn
3
Depressive symptoms
3
polyuria
3
sore throat
3
memory loss
3
rundown
2
Fluctuation
2
Neurologic symptoms
2
rigors
2
hoarseness
2
dental pain
2
renal colic
2
Pain at rest
2
Cardiovascular symptoms
2
tonic-clonic seizure
2
chills
2
polydipsia
2
Gastrointestinal symptoms
2
musculoskeletal chest pain
2
Excitability
2
paraparesis
2
pleuritic chest pain
2
abdominal discomfort
2
incoordination
2
muscle cramps
2
facial pain
2
hypotonia
2
muscle rigidity
2
spasticity
2
neuralgia
2
S3 gallop
2
eds
2
No pain
2
ophthalmoplegia
2
more...
Drug
Cardiovasc
2063
Monit
703
nitroglycerin
426
ROS
94
vitamin E
86
NADH
71
ascorbate
58
Dial
57
TTC
56
Nephron
39
Ranolazine
36
Ranolazine
36
caffeine
29
Angiotensin II
28
MAP
27
ROC
27
lysine
24
ETA
24
Dermatol
23
Captopril
23
Vitamin E
22
Indomethacin
21
Clopidogrel
20
Propofol
20
ICI
20
Molsidomine
19
Adenosine triphosphate
18
Levosimendan
17
Simvastatin
14
niacin
14
Ringer's solution
13
Nephron
13
CSF
13
Albumin
13
Leaf
12
Pravastatin
12
Atenolol
12
citric acid
11
TAT
11
Heme
10
Clonidine
10
Viagra
10
Asthma
10
MRC
10
Estrogens
10
Abciximab
10
Atropine
10
Ramipril
9
Rosuvastatin
9
Felodipine
9
EE2
9
Timolol
9
Inderal
8
Glucagon
8
CPR
8
Parkin
8
CTA
8
Parkin
8
Amrinone
8
ADM
8
DNase I
8
Digitalis
8
Lovastatin
8
Clofibrate
8
Histamine
8
Fraction
7
Ginseng
7
Bezafibrate
7
Ouabain
7
Nitric Oxide
7
Rosiglitazone
7
Trapidil
7
Fentanyl
7
Phentolamine
6
Coral
6
IL-2
6
Viagra
6
Sodium nitroprusside
6
CVA
6
APD
6
Spectrum
6
EPI
6
PFA
6
EPA
6
Gel
6
Perindopril
6
Fluorescein
5
Theophylline
5
Tetrofosmin
5
Hypaque
5
Regadenoson
5
ABC
5
IFN-gamma
5
PTH
5
Antithrombin III
5
VCR
5
Enoximone
5
Isoptin
5
Iloprost
5
Acadesine
4
Growth hormone
4
Methylprednisolone
4
Aggrastat
4
Palmitoyl
4
Serum albumin
4
CaCl2
4
Forskolin
4
pyridoxal phosphate
4
FAD
4
SMP
4
Arbutamine
4
Isradipine
4
ENT
4
AGG
4
GHRP
4
Aliskiren
4
Growth hormone
4
BH4
4
p75
4
Valsartan
4
Perhexiline
4
Vitamin K
4
Eptifibatide
4
Ethanol
4
Fragmin
4
CTX
4
Brevibloc
3
Raloxifene
3
G-CSF
3
Levovist
3
Ulinastatin
3
PCP
3
Alteplase
3
Tacrolimus
3
Bosentan
3
CaCl2
3
Optison
3
Brevibloc
3
Aloe
3
CaCl2
3
Helium
3
Dopexamine hydrochloride
3
Fluorescein
3
lactose
3
Hypaque
3
CIA
3
Gemfibrozil
3
ADR
3
CTT
3
uPA
3
Epoetin
3
Triad
3
Nadolol
3
Cidofovir
3
Aprotinin
3
Epigallocatechin
3
Tedisamil
3
Optison
3
Vitamin B12
3
Gliclazide
3
more...
Enzyme
creatine kinase
769
superoxide dismutase
420
lactate dehydrogenase
415
ACE
300
mitogen-activated protein kinase
282
caspase-3
282
renin
268
peroxidase
194
protein kinase
179
catalase
159
protein kinase C
155
thrombin
154
ATPase
142
AMP-activated protein kinase
129
ERK
117
NO synthase
102
glutathione peroxidase
98
CAD
96
CAD
96
CAD
96
luciferase
89
phosphodiesterase
82
xanthine oxidase
81
aspartate aminotransferase
79
tissue plasminogen activator
77
AMPK
65
AMPK
60
NOS
54
phospholipase A2
52
PARP
48
NADPH oxidase
47
focal adhesion kinase
46
GSK
45
ACS
45
complex I
44
NADPH oxidase
42
phosphatidylinositol 3-kinase
42
thromboplastin
39
proteasome
39
caspase-9
37
APC
37
guanylate cyclase
36
adenylate cyclase
32
alanine aminotransferase
29
caspase-1
27
lipoxygenase
27
lipoprotein lipase
26
phosphoinositide 3-kinase
26
calcineurin
25
AST
25
urokinase-type plasminogen activator
24
succinate dehydrogenase
23
heme oxygenase
23
kallikrein
23
phospholipase C
22
plasmin
22
MEK
21
reverse transcriptase
21
MAP
21
trypsin
21
glutathione reductase
20
ATP synthase
19
caspase-8
18
alkaline phosphatase
18
pyruvate dehydrogenase
17
aldehyde dehydrogenase
17
RNase
17
RNase
17
3-hydroxy-3-methylglutaryl coenzyme A reductase
16
collagenase
16
cathepsin D
16
aldehyde dehydrogenase
15
pyruvate dehydrogenase
15
pyruvate dehydrogenase
15
aldehyde dehydrogenase
15
aldehyde dehydrogenase
15
aldehyde dehydrogenase
15
acetylcholinesterase
14
cytochrome oxidase
14
adenosine deaminase
14
IKK
14
adenosine deaminase
14
CaMKII
14
phosphorylase
13
PKG
13
neutrophil elastase
13
cholinesterase
13
5'-nucleotidase
13
lipase
12
hyaluronidase
12
hyaluronidase
12
CD10
12
CCS
12
gamma-glutamyl transpeptidase
12
CPT
11
monoamine oxidase
11
glutathione S-transferase
11
xanthine dehydrogenase
11
CPR
11
TAT
11
diaphorase
10
prolyl hydroxylase
10
arginase
10
NQO1
10
chymase
10
PDE
10
MIP
10
phosphofructokinase
10
RNA polymerase
9
KAT
9
beta-glucuronidase
9
ceruloplasmin
9
beta-galactosidase
9
tryptase
8
methylenetetrahydrofolate reductase
8
aldose reductase
8
cathepsin B
8
MMP
8
citrate synthase
8
tissue kallikrein
8
elastase
8
methylenetetrahydrofolate reductase
8
tyrosine hydroxylase
8
TdT
7
paraoxonase
7
lysozyme
7
paraoxonase
7
cholesterol acyltransferase
7
DNase
7
glucose-6-phosphate dehydrogenase
6
NADH dehydrogenase
6
transcriptase
6
SCS
6
PDK1
6
CYP3A4
6
mu-calpain
5
calcium pump
5
lysyl oxidase
5
myosin ATPase
5
acid phosphatase
5
P-glycoprotein
5
glyceraldehyde-3-phosphate dehydrogenase
5
LMT
5
E-2
5
myosin light chain kinase
5
hexokinase
5
neuropathy target esterase
5
SMP
4
GCA
4
caspase-7
4
CPT
4
matrix metalloproteinase 2
4
AMP deaminase
4
ECH
4
SPT
4
cystathionine beta-synthase
4
acyl-CoA dehydrogenase
4
caspase-7
4
alpha-glucosidase
4
malonyl-CoA decarboxylase
4
more...
Compound
Cardiol
3946
oxygen
2234
Dec
2033
Clin
1897
calcium
1417
glucose
951
ATP
620
sodium
573
nitric oxide
547
potassium
522
water
327
DNA
318
acetate
276
phosphate
266
creatinine
234
prostacyclin
228
TNF
221
CO2
217
arginine
206
ADP
196
nitrate
182
hydrogen
159
His
155
Hearts
154
Hearts
154
ADP
145
ADP
144
noradrenaline
137
nitrogen
131
iron
128
salt
118
aldosterone
118
GSH
110
GSH
110
ASA
109
Adenosine
109
homocysteine
107
Insulin
99
ethanol
90
Dobutamine
85
iodine
84
dUTP
83
Dipyridamole
80
Dipyridamole
80
Dipyridamole
80
Dipyridamole
80
MDA
77
copper
76
Verapamil
75
cGMP
74
AMP
73
cysteine
72
Verapamil
71
H2O2
71
NADH
71
TTC
68
Nitroglycerin
68
sulfate
68
H2S
67
cAMP
66
Cholesterol
66
zinc
66
NAD
65
MTT
65
Mg2+
65
phosphocreatine
64
Propranolol
63
urea
63
Diltiazem
61
Diltiazem
61
Propranolol
57
Dial
57
Nifedipine
55
nicotinamide
54
Angiotensin II
54
BNP
53
tyrosine
52
alanine
50
Lactate
50
NAD
50
methionine
47
selenium
47
glutamate
46
Isoproterenol
46
serine
45
ACS
45
ACS
45
phosphorus
45
vitamin D
44
Pac
43
ammonia
42
Ang II
42
Cocaine
40
galactose
39
Melatonin
38
Fibrinogen
37
Nicorandil
37
lysine
37
bromide
36
PCI
36
Optimal
36
prostaglandin E1
36
5-HT
36
H2S
35
Amiodarone
35
CoA
35
N-acetylcysteine
35
GMP
35
Phe
33
AHA
33
L-carnitine
33
pentadecanoic acid
32
pentadecanoic acid
32
Heparin
31
coenzyme Q10
31
superoxide radical
31
Carvedilol
30
cobalt
30
threonine
30
glycerol
29
nicotinic acid
29
leucine
29
caffeine
29
NH2
28
Adrenal
28
Atorvastatin
28
TXA2
26
Diabetol
26
ICI
26
MAP
25
aldehyde
25
ISDN
25
Thyroid
25
Norepinephrine
25
manganese
25
palmitic acid
25
Vitamin E
25
PGE2
24
Sodium
24
cyanide
24
Off
24
ETA
24
ACh
24
N2O
23
Lidocaine
23
PEG
23
Sildenafil
23
Amlodipine
22
nicotinic acid
22
Thrombin
22
TSH
22
Esmolol
22
Estrogen
21
glutamine
21
nicotinic acid
21
nicotinic acid
21
Estrogen
21
fluorine
21
Salt
21
palmitic acid
20
more...