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Target Concepts:
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Query: UMLS:C0151744 (
myocardial ischemia
)
31,282
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
18
F-labeled fluorodeoxyglucose positron emission tomography (
18
F-FDG PET) is the most sensitive tool for studying brain metabolism in vivo. We investigated the image patterns of
18
F-FDG PET during reperfusion injury and correlated changes of whole brain blood flow utilizing a rat
myocardial ischemia
/reperfusion injury (MIRI) model. The results assessed by echocardiography indicated resultant cardiac dysfunction after ischemia-reperfusion in the rat heart. It was found that the average standardized uptake value (SUV
average
) of the whole brain was significantly decreased in model rats, and the glucose uptake of different brain regions including accumbens core/shell (Acb), left caudate putamen (LCPu), hippocampus (HIP), left hypothalamus (LHYP), olfactory (OLF), superior colliculus (SC), right midbrain (RMID), ventral tegmental area (VTA), inferior colliculus (IC) and left thalamus whole (LTHA) was significantly decreased in MIRI rats whereas no significant difference was found in the SUV
average
of amygdala (AMY), right CPu, RHYP, right HYP, left MID, right
THA
, pons and medulla oblongata (MO). These
18
F-FDG PET data provide a reliable identification method for brain metabolic changes in rats with MIRI.
...
PMID:Mapping Changes of Whole Brain Blood Flow in Rats with Myocardial Ischemia/Reperfusion Injury Assessed by Positron Emission Tomography. 3134 4
