Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0151744 (myocardial ischemia)
 31,282 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In patients with ischemic heart disease (IHD), neurocirculatory dystonia (NCD) and acute myocardial infarction (AMI), we observed significant, positive, linear correlations between total concentration of non-etherified fatty acids (NEFA) as well as between the percentage of individual fatty acids in arterial and coronary sinus blood. Correlation analysis of the results demonstrated that in patients with IHD and NCD there is significant myocardial NEFA extraction which is highly reduced by electrically induced myocardial ischemia in patients with IHD and by increased myocardial load in patients with NCD. These changes are more evident in patients with IHD. Patients with AMI exhibited minor myocardial NEFA extraction, similar to that in patients with IHD after stimulation, but much higher NEFA concentration in arterial and coronary sinus blood. Determination of NEFA levels in arterial and coronary sinus blood in patients with AMI and their temporal dynamics may be helpful for evaluation of the degree of the disease severity and can also be of prognostic value.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Effect of ischemic state on myocardial utilization of nonesterified fatty acids]. 342 22

Parameters of haemodynamic and myocardial oxygen supply under effect of 1.0-2.0 vol.% Halothane and Enfluran were studied under conditions of surgical stress in 12 patients with IHD of the III-IV functional classes. It was found out that the heart work and oxygen demand decreased in parallel to increase in dose of anesthetics and were adequately provided by the coronary blood flow. No signs of myocardial ischemia were determined.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Comparative evaluation of the effect of halothane and enflurane on the myocardial function and metabolism in patients with ischemic heart disease]. 342 25

Results of 408 cases of anesthesia in patients with IHD, arterial hypertension, disturbances of heart rate and conduction are analysed. Medical treatment up to the day of operation, use of anesthetics which have moderate depressive effect on the myocardial contractility and work, administration of vasodilators and beta-blockers made it possible to avoid severe disturbances of hemodynamics during the perioperative period. Perioperative myocardial infarction was observed in 5% cases of myocardial revascularization and in 0.3% of all the other operations.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1987
PMID:[Anesthetic tactics in surgical interventions in patients with cardiovascular diseases]. 342 26

Ten patients with ischemic heart disease and stable angina of effort have been examined for the possibility of tolerance development to verapamil antianginal effect, which was assessed using bicycle ergometry. Antianginal effect after the course of treatment with 80 mg of verapamil 3-4 times per day, and 120 mg of verapamil 3-4 times per day, was significantly more pronounced than after single administration of 80 and 120 mg of the drug. Thus, no tolerance to verapamil antianginal effect was observed during the course of treatment with verapamil, moreover the effect was enhanced.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1984
PMID:[Possibility of developing tolerance to the antianginal effect of verapamil]. 650 32

The work presents the results of the study of tolerance to exercise test in 677 men aged 40-59, carried out during a cross-sectional epidemiologic study. Persons with positive electrocardiographic results of the test were shown to be characterized by a diminished tolerance to exercise, the duration of the test and cardiac index being informative indicators together with such IHD risk factors as blood serum cholesterol level and age.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1983
PMID:[Physical load tolerance examined in epidemiological studies]. 686 Apr 82

A total of 60 patients with coronary heart disease were examined and divided into 2 groups: (I)53 patients with classical angina pectoris at rest and of effort; (II)7 patients with variant angina pectoris. The results of 24-hour ECG monitoring, bicycle exercise test and coronary angiography were studied. By giving an objective ECG pattern during myocardial ischemia attack. 24-hour ECG monitoring enabled one to differentiate various clinical forms of angina pectoris, establish their connection with heart rhythm disturbances, thus forming the basis for the differential approach to the treatment.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1983
PMID:[24-hour ECG monitoring of patients with different clinical forms of stenocardia]. 686 Apr 84

A total of 27 patients were examined: 12 of them had non-coronarogenic cardialgias and 15 had ischemic heart disease. Prostaglandin E2 intravenous infusion followed the coronary angiography and ventriculography against the background of stabilized pressure in the left ventricle. The infusion lasted 10 minutes, then ventriculography was repeated. The total dose of prostaglandin E2 was 0.5-1.5 mg. Prostaglandin E2 had positive chronotropic and inotropic effects, as well as hypotensive and venodilatative ones. Stroke volume was decreased in most observations. Prostaglandin E2 eliminated the attacks of cardiac asthma and angina pectoris, caused by the increase of the left ventricle cavity.
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR 1982
PMID:[Effect of intravenous prostaglandin E2 administration on central hemodynamics in ischemic heart disease patients]. 695 70


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