Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0149958 (
complex partial seizures
)
2,563
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 42-year-old man with human
immunodeficiency
virus (HIV) infection and a history of
complex partial seizures
developed severe anemia after the addition of valproic acid to his stable antiretroviral regimen of zidovudine, lamivudine, and abacavir. The inhibition of zidovudine glucuronidation by valproic acid and the resultant zidovudine hematologic toxicity is the proposed mechanism of the interaction.
...
PMID:Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid. 1498 71
