Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0149925 (
small cell lung cancer
)
6,491
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
392
p53
197
Mol
189
tyrosine kinase
169
EGFR
152
neuron-specific enolase
124
epidermal growth factor receptor
98
bombesin
94
P-glycoprotein
69
Bcl-2
67
NSE
67
TNM
65
Pol
63
MRI
63
somatostatin
62
gastrin-releasing peptide
62
gastrin
60
enolase
59
c-myc
57
topoisomerase I
55
receptor tyrosine kinase
54
CEA
50
She
50
carcinoembryonic antigen
48
vasopressin
47
nodal
45
CD56
45
lactate dehydrogenase
45
MYC
44
FDG
43
RB1
43
CAV
42
granulocyte colony-stimulating factor
42
caspase-3
42
vascular endothelial growth factor
42
ATP
40
substance P
40
PD-L1
39
ACTH
39
synaptophysin
39
cytokine
38
GRP
37
N-myc
37
p21
35
chromogranin A
35
granulocyte
35
ras
34
polypeptide
34
ALK
34
mTOR
34
AKT
34
PD-1
34
albumin
33
MET
33
alkaline phosphatase
32
Mal
32
interferon
32
CSF
32
L-myc
31
c-kit
31
LDH
31
calcitonin
31
glycoprotein
31
SCC
29
PARP
28
non-Hodgkin's lymphoma
28
cage
27
ASCL1
27
VEGF
27
PI3K
27
proto-oncogene
26
E-cadherin
26
stem cell factor
26
serum albumin
26
beta-endorphin
25
G-CSF
25
IFN
25
p16
25
bcl-2
24
creatine kinase
24
more...
Disease
small cell lung cancer
6491
cancer
2838
lung cancer
2075
tumor
1947
non-small cell lung cancer
1213
lung carcinoma
589
metastases
522
adenocarcinoma
470
carcinoma
398
squamous cell carcinoma
238
breast cancer
230
neutropenia
163
tumor growth
153
brain metastases
150
myelosuppression
133
melanoma
128
thrombocytopenia
120
tumorigenesis
118
primary tumor
113
lymphoma
103
ovarian cancer
102
carcinoid
97
leukemia
95
carcinogenesis
94
tumor progression
89
leukopenia
88
paraneoplastic syndrome
87
prostate cancer
81
Lambert-Eaton myasthenic syndrome
77
mesothelioma
74
pneumonia
72
anemia
71
neuroblastoma
71
neuroendocrine carcinoma
68
extensive stage SCLC
62
encephalitis
59
limited-stage small cell lung cancer
53
colorectal cancer
49
colon cancer
49
neuropathy
47
retinoblastoma
46
renal cell carcinoma
46
Hodgkin's disease
46
gastric cancer
45
squamous cell lung cancer
42
sarcoma
41
lymphadenopathy
40
bone metastases
40
neuroendocrine tumor
39
bronchogenic carcinoma
39
Thoracic
37
Small cell carcinoma
36
pancreatic cancer
36
liver metastases
35
multiple myeloma
32
encephalomyelitis
32
adenocarcinoma of the lung
32
Cushing's syndrome
31
lung disease
31
sensory neuropathy
30
non-Hodgkin's lymphoma
29
recurrent SCLC
29
stage III NSCLC
29
acute myeloid leukemia
28
sepsis
28
esophagitis
26
medullary thyroid carcinoma
26
epithelial ovarian cancer
26
glioma
26
residual disease
25
MCF
24
diabetes
24
Merkel cell carcinoma
24
bone marrow metastases
24
hepatocellular carcinoma
23
sepsis
23
aggressiveness
23
large cell carcinomas
23
tuberculosis
23
hypertension
22
more...
Symptom
vomiting
66
weakness
64
nausea
59
diarrhea
56
dyspnea
47
cough
45
fatigue
43
pain
43
nausea and vomiting
40
seizures
24
ataxia
23
anorexia
22
headache
21
myoclonus
18
abdominal pain
17
paresthesia
16
chest pain
15
cerebellar ataxia
14
hemoptysis
12
constipation
11
erythema
9
cachexia
9
dizziness
8
numbness
8
dysesthesia
8
hoarseness
8
polyuria
7
chorea
7
anesthesia
7
myalgia
7
back pain
7
lethargy
6
starvation
6
discomfort
6
shortness of breath
6
dysarthria
6
discomfort
5
arthralgia
5
asthenia
5
memory loss
5
polydipsia
5
sleepiness
4
exhaustion
4
tremor
4
overweight
4
hepatomegaly
4
vertigo
4
epigastric pain
3
low back pain
3
bone pain
3
productive cough
3
ataxic gait
3
Cushingoid
3
tingling
3
Cushingoid
3
persistent cough
3
respiratory distress
3
blurred vision
3
hemiplegia
3
chills
3
abdominal discomfort
2
muscle stiffness
2
decreased appetite
2
tonic-clonic seizure
2
hypothermia
2
forgetfulness
2
photophobia
2
angina
2
chronic cough
2
hyperesthesia
2
muscle cramps
2
HSA
2
syncope
2
hepatosplenomegaly
2
incoordination
2
flushing
2
hyperoxia
2
wheezing
2
dystonia
2
exertional dyspnea
1
more...
Drug
Etoposide
67
CPT-11
47
TTC
44
CSF
44
Adriamycin
34
Taxol
34
CTX
31
G-CSF
27
Cardiovasc
22
Irinotecan
21
IL-2
20
Docetaxel
20
VCR
20
ADM
19
VCR
16
IFN-gamma
15
Vinorelbine
14
Pemetrexed
14
Gefitinib
14
ABC
13
Teniposide
13
CTX
12
CTX
12
Bevacizumab
11
Erlotinib
10
lysine
10
Taxotere
9
GEO
9
MRC
8
Navelbine
8
ADR
8
Paraffin
7
ROC
6
Gemzar
6
ROS
6
Gleevec
6
Monit
6
Amifostine
6
Herceptin
6
Alimta
5
Imatinib
5
HCG
5
Dermatol
5
Retinoic acid
4
BLM
4
DM1
4
Marimastat
4
Glutathione
4
Oxaliplatin
4
CAM
4
CTC
3
Cetuximab
3
Prednisone
3
Etoposide phosphate
3
Filgrastim
3
Sandostatin
3
Rituximab
3
DNase I
3
MAP
3
ICI
3
Tarceva
3
Mutagen
3
Arsenic trioxide
3
Serum albumin
3
CTC
3
Cremophor EL
3
vitamin E
3
Ipilimumab
3
Diamminedichloroplatinum
3
Bortezomib
3
Sandostatin
3
Podophyllum
2
Growth hormone
2
uPA
2
Satraplatin
2
Mitomycin-C
2
Leaf
2
ETA
2
nitroglycerin
2
NVP
2
more...
Enzyme
ERK
276
topoisomerase
77
topoisomerase
73
mitogen-activated protein kinase
70
P-glycoprotein
69
enolase
61
lactate dehydrogenase
51
focal adhesion kinase
41
protein kinase
37
protein kinase C
35
caspase-3
33
alkaline phosphatase
32
creatine kinase
31
PARP
29
luciferase
25
glutathione S-transferase
23
reverse transcriptase
19
phosphatidylinositol 3-kinase
18
proteasome
13
MEK
13
caspase-9
12
RNA polymerase
12
urokinase-type plasminogen activator
12
RNase
11
RNase
11
trypsin
11
ricin
10
caspase-8
10
cdc2
10
ATPase
9
MDR
9
CPT
9
thymidine kinase
9
APC
9
CPT
9
peroxidase
9
gamma-glutamyl transpeptidase
9
CPT
9
ACE
8
phosphoinositide 3-kinase
8
phospholipase C
8
thrombin
8
caspase-1
7
acetylcholinesterase
7
MMP
7
STK11
7
ACS
7
adenylate cyclase
6
alcohol dehydrogenase
6
AMPK
6
endonuclease
6
SPC
6
DNA methyltransferase
6
ADH
6
thymidylate synthase
6
AMPK
6
Alternating
6
GSK
6
AMP-activated protein kinase
6
NQO1
5
chitinase
5
glutathione reductase
5
plasmin
5
catalase
5
alanine aminotransferase
5
glutathione peroxidase
4
transcriptase
4
IKK
4
cathepsin B
4
collagenase
4
farnesyltransferase
4
DOPA decarboxylase
4
aspartate aminotransferase
4
granzyme B
4
glyceraldehyde-3-phosphate dehydrogenase
4
DNA polymerase
4
calcineurin
4
farnesyltransferase
4
IMP dehydrogenase
3
neuraminidase
3
more...
Compound
Clin
494
DNA
466
Dec
459
VP-16
152
calcium
105
DDP
96
tyrosine
74
MTT
69
TNM
65
CBDCA
64
CBDCA
64
methionine
59
sodium
49
CPT-11
47
oxygen
45
Adriamycin
45
ATP
40
glucose
40
ACTH
37
Topotecan
36
Topotecan
36
leucine
33
His
32
water
32
CTX
31
Paclitaxel
29
SCC
29
arginine
28
serine
27
acetate
26
cAMP
26
Phe
23
CCNU
22
bromide
22
GSH
22
retinoic acid
22
GSH
22
lysine
21
NH2
21
phosphate
20
ADR
20
GM1
20
SN-38
19
MSM
19
DMS
19
creatinine
19
threonine
18
iodine
17
Ifosfamide
17
VM-26
16
ACNU
16
Pac
16
H-69
15
Docetaxel
14
TNF
14
galactose
14
cysteine
14
sulfate
14
Asp
13
GAL
13
PVP
13
potassium
12
GD3
12
Gemcitabine
11
fluorine
11
PCI
11
Gemcitabine
11
DTPA
11
boron
11
GM2
11
iron
11
PEG
10
tryptophan
10
tryptophan
10
tryptophan
10
tryptophan
10
zinc
9
CPT
9
CPT
9
pyrimidine
9
more...