Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0149925 (small cell lung cancer)
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Human Gene/Protein
MHC class II HLA-DR-beta 12.3
LIX1L 12.3
SAX3 12.3
GPR137C 12.3
HOXD8 protein 11.3
ZNF560 11.3
G protein-coupled receptor 19 11.3
GAGE7 11.3
IRF2 protein 10.7
ZNF512 10.7
Family with sequence similarity 46, member A 10.7
JTK5 10.7
preprogastrin-releasing peptide 10.7
semaphorin A(V) 10.3
STI2 10.3
EMLP 10.3
PTEN2 10.3
HELT 10.3
serine/threonine kinase 33 10.3
ARHGEF19 9.9
GPN3 9.9
APRG1 9.9
KIAA1432 9.9
PROSTATE 9.9
TUBA4B 9.9
Nuclear factor I/B 9.9
SLIT2 protein 9.9
CyP33 9.9
MS4A8B 9.9
L-myc protein 9.8
BEC2 9.7
Retinol dehydrogenase 12 9.7
DNAJC2 9.7
tumor necrosis factor receptor superfamily member 1A 9.7
RAB15 9.7
Neuroendocrine-specific protein 9.7
JUB 9.5
CNKSR3 9.5
TUSC5 9.5
GMPPA 9.5
more...
Disease
combined type SCLC 12.3
oat cell type lung cancer 12.3
small cell lung cancer 12.3
Paraneoplastic optic neuropathy 11.7
extensive stage SCLC 11.7
recurrent SCLC 11.7
limited-stage small cell lung cancer 11.3
Paraneoplastic neuropathy 11.3
Myasthenic syndrome 10.9
LCA3 10.7
Well-differentiated neuroendocrine carcinoma 10.7
Non-small cell carcinoma 10.7
Paraneoplastic encephalomyelitis 10.4
Paraneoplastic encephalitis 10.3
small cell lung cancer stage 10.3
cancer associated retinopathy 10.1
Atypical carcinoid tumor 9.9
Typical carcinoid 9.8
LCA2 9.8
large cell lung cancer 9.7
stage II NSCLC 9.7
Ectopic ACTH syndrome 9.4
relapsed testicular cancer 9.3
Bulbar weakness 9.3
Lambert-Eaton myasthenic syndrome 9.2
bone marrow metastases 9.1
squamous cell lung cancer 9.0
Basaloid carcinoma 8.9
Congenital Myasthenic Syndromes 8.8
DIPNECH 8.8
Opsoclonus myoclonus 8.7
Secondary adrenal insufficiency 8.7
Ocular flutter 8.7
Trichosporon beigelii infection 8.7
Neutropenic colitis 8.7
Paraneoplastic cerebellar degeneration 8.6
stage III NSCLC 8.6
stage IV NSCLC 8.4
HPC4 8.4
recurrent vulvar cancer 8.4
more...
Symptom
Truncal ataxia 8.9
stomach cramps 6.7
Cushingoid 6.1
Sister Mary Joseph's nodule 6.0
Cushingoid 6.0
Lhermitte's sign 5.9
generalized erythema 5.4
dysesthesia 5.4
bigeminal 5.3
hypalgesia 4.8
ataxic gait 4.7
arm weakness 4.7
persistent cough 4.6
myoclonus 4.4
nausea and vomiting 4.4
cerebellar ataxia 4.3
hyperesthesia 4.2
body pain 4.2
non-productive cough 4.1
chorea 4.0
right lower quadrant pain 4.0
paresthesia 4.0
forgetfulness 3.9
testicular pain 3.8
hoarseness 3.7
loss of taste 3.7
productive cough 3.7
Scratch 3.6
nausea 3.6
tingling 3.5
polyuria 3.5
polydipsia 3.5
muscle cramps 3.4
orthopnea 3.4
vomiting 3.3
syncopal episodes 3.3
hemoptysis 3.3
cough 3.2
asthenia 3.2
decreased appetite 3.1
more...
Drug
Aqupla 12.3
Depreotide 9.9
Becatecarin 9.7
Etoposide phosphate 9.6
Teniposide 9.4
Satraplatin 8.5
Alimta 8.3
Etoposide 8.2
Prinomastat 8.1
Marimastat 8.1
Sulofenur 7.9
Edatrexate 7.9
Navelbine 7.8
Paraplatin 7.7
Arachidonic Acid 7.6
Lenograstim 7.5
Aclarubicin 7.5
Pemetrexed 7.4
Vinorelbine 7.3
Menogaril 7.3
Gemzar 7.3
Tetrofosmin 7.0
Irinotecan 7.0
VCR 7.0
CPT-11 6.9
TTC 6.9
Epoetin beta 6.6
Tykerb 6.5
Genasense 6.4
Amifostine 6.3
OctreoScan 6.3
Fotemustine 6.2
Vandetanib 6.2
Taxotere 6.1
Diamminedichloroplatinum 6.1
Tarceva 6.1
Erlotinib 6.0
Gallium nitrate 6.0
VCR 6.0
Podophyllum 5.9
more...
Enzyme
EC 3.4.19.1 7.9
TUT 7.6
enolase 6.3
STK11 6.2
adamalysin 6.0
EC 2.6.1.16 5.8
methylenetetrahydrofolate dehydrogenase 5.5
LDT 5.4
amidophosphoribosyltransferase 5.3
spermidine/spermine N1-acetyltransferase 5.3
topoisomerase 5.3
topoisomerase 5.3
methylenetetrahydrofolate dehydrogenase 5.0
N-acetylglucosaminyltransferase V 4.9
GD3 synthase 4.7
P-glycoprotein 4.7
methionine synthase reductase 4.6
lambda exonuclease 4.6
choline kinase 4.5
eEF2 kinase 4.4
endo-N 4.4
esterase D 4.3
SOR 4.3
farnesyltransferase 4.2
Alternating 4.2
DOPA decarboxylase 4.2
aromatic L-amino acid decarboxylase 4.2
MTD 4.0
IMP dehydrogenase 4.0
histone demethylase 4.0
ricin 3.9
propionyl-CoA carboxylase 3.9
propionyl-CoA carboxylase 3.8
argininosuccinate synthetase 3.8
ERK 3.8
deoxycytidine kinase 3.8
CPT 3.8
ADH 3.7
squalene epoxidase 3.7
farnesyltransferase 3.7
more...
Compound
AD-143 11.3
Polyporic acid 10.7
6-chloro-1H-indole 10.7
H-69 10.2
H-82 9.9
Mordant Yellow 10 9.7
SP-G 9.1
Topotecan 8.8
Aristeromycin 8.8
Rhizoxin 8.5
Topotecan 8.3
BCME 8.2
Tetraplatin 8.1
Deoxydoxorubicin 8.1
VP-16 7.9
2-phenylnaphthalene 7.9
CBDCA 7.8
CBDCA 7.8
Rebeccamycin 7.7
4-iodobenzamide 7.5
M 14 7.5
Nitrosamine 7.3
Ifosfamide 7.3
AD 32 7.3
THP-ADM 7.3
NMHE 7.1
CPT-11 6.9
ACNU 6.9
Mesna 6.9
CCNU 6.9
MK 571 6.9
CPH 6.8
PCNU 6.8
3,4-DAP 6.7
ICRF-187 6.6
Amifostine 6.5
VM-26 6.5
SN-38 6.4
CoM 6.4
ICI 164384 6.2
more...