Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149871 (deep vein thrombosis)
12,364 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The usefulness and limitation of intraoperative angioscopy in the field of cardiovascular surgery were investigated based on our clinical experience. Considerable leakage of cardioplegic solution through the aortic valve due to valve regurgitation was angioscopically demonstrated when the infusion pressure in the aortic root was less than 10 mmHg. This indicates that the cardioplegia must be infused with an aortic pressure of above 20 mmHg for appropriate myocardial protection. After thromboendarterectomy on the arteriosclerosis obliterans, fixation with the edge of the residual intimal flap to the arterial wall was performed correctly under direct visualization. The status of thrombus organization in deep vein thrombosis was evaluated. Even after complete thrombectomy, iliac compression was still demonstrated. Blood in the cardiovascular lumen can be easily cleaned by saline flushing. However, careful attention to fluid overloading must be employed when the observation period is prolonged.
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PMID:[Intraoperative fiber optic angioscopy during cardiovascular surgery]. 318 96

The authors review the importance of echocardiography and duplex examination of the blood vessels of the lower extremities for early diagnosis of thromboembolic attacks. Echocardiographic examination rules out other causes of the patient's complaints such as myocardial infarction, heart defects, ischaemic heart disease and others. The main role of echocardiography is, however, detection of symptoms of an acute rise of the blood pressure in the right heart or symptoms of its failure. The most valuable symptom is dilatation of the right branch of the pulmonary artery and dilatation of the right ventricle found in as many as 75% patients. It is also useful to assess by the Doppler method the dextrolateral systolic pressure from tricuspidal regurgitation. For pulmonary embolism a regurgitation rate of 2.8-3.8 m/s is typical. The correlation coefficient is, however, lower than when the dimensions of the right and left ventricle are used. Evidence of deep venous thrombosis does not reveal pulmonary embolism but has the same therapeutic consequences. Duplex sonography has a 95-100% sensitivity and specificity in acute thrombosis. In recurrent thrombosis it is necessary to use a combination of the two methods. Concurrent echocardiography and duplex sonography of the blood vessels of the lower extremities makes it possible to start prompt treatment in 70-80% of the patients. In the remainder for diagnosis of thromboembolic attacks other methods must be used.
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PMID:[Ultrasound in the diagnosis of thromboembolism]. 814 Jul 53

Dual antiplatelet therapy is currently recommended for all patients with acute coronary syndromes, independent of whether they receive pharmacological treatment or undergo percutaneous coronary intervention. Antiplatelet agents are the cornerstone of pharmacological treatment in interventional cardiology. However, there is a clear need for randomized trials to assess the treatment strategy of dual antiplatelet therapy in patients who also need long-term antithrombotic treatment (such as those with atrial fibrillation, prosthetic heart valve, mitral valve regurgitation or stenosis, deep vein thrombosis, pulmonary embolism, or pulmonary hypertension). In this paper we discuss trials and analyses on the use of dual antiplatelet treatment in combination with antithrombotic therapy in particular diseases, with a focus on the risk of hemorrhagic events connected with this treatment, as well as recent guidelines of the European Society of Cardiology, the American College of Cardiology, and the American Heart Association.
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PMID:Dual antiplatelet therapy and antithrombotic treatment: Recommendations and controversies. 1938 70