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Query: UMLS:C0149871 (deep vein thrombosis)
 12,364 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two hundred and forty-seven phlebograms (113 bilateral and 21 unilateral) were performed in 134 patients 10--14 days after total hip replacement. Fifty-eight per cent of the patients were found to have deep vein thrombosis. The patients with DVT were significantly older than patients without DVT, but there was no difference regarding sex, type of hip prosthesis, side of operation or day of mobilization. No difference was found in the duration of operation and anaesthesia, the operative haemorrhage and the amount of bank blood transfused in patients with and without DVT. Fifty per cent of the thrombi were confined to the calf veins. Ninety-seven per cent of these thrombi were asymptomatic and were as frequent on the operated as on the non-operated side. The remaining 50 per cent of the thrombi engaged the thigh with or without simultaneous calf vein involvement. These thrombi produced symptoms in 23 per cent of the cases and were significantly more common on the operated than on the non-operated side. It is concluded that DVT after hip replacement can be of two different types: thrombosis caused by stasis and the general effects of trauma and thrombosis caused by local factors involving the thigh veins of the operated leg.
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PMID:Deep vein thrombosis after total hip replacement: a clinical and phlebographic study. 44 49

A perspective study by the Royal College of General Practitioners reported that the risk of developing deep venous thrombosis of the legs in women taking oral contraceptives was 5.66 times higher than women not on medication. Estrogen-progestogen compounds are highly potent hormones that produce alterations in metabolic and endocrine functions. Clinical examination of the leg is the most reliable method of determining the earliest indication of thrombophlebitis even with the latest diagnostic tools of venography. The key to diagnosis and treatment of pulmonary embolism, which often occurs with patients with thrombophlebitis, is a patient's complaint of leg pains. Those who have undergone surgery, especially abdominal and pelvic, are bedridden, and those who are taking oral contraceptives are at risk of thrombophlebitis. Deep thrombophlebitis of the leg is not recognized clinically in 50-80% of those with venographically documented thrombophlebitis because the signs and symptoms are so protean. Treatment with heparin and leg bandages is most common. Heparin is often followed with coumarin therapy. Some methods of diagnosis are calf tenderness, edema, skin temperature, Homan's Sign, Lowenberg's Sign, Pratt's Sign, cyanosis, systemic signs, and contrast venogram.
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PMID:A review of the birth control pill and its relationship to thrombophlebitis. 44 35

Complications are the major causes of illness and death after burning and most of them stem from the burn wound. Their origin and importance are reviewed with emphasis on problems and growing points in knowledge. Fluid leakage from the circulation into the burn is the cause of hypovolemic shock, but the underlying permeability changes in the burn are only partly understood. Other nonbacterial complications include acute cardiac failure, acute anemia, hemolytic jaundice, renal failure, encephalopathy, complex hypermetabolic effects including pseudodiabetes, gastric and duodenal ulceration, deep vein thrombosis and pulmonary embolism, pulmonary and glomerular microthrombosis, hepatic jaundice, and arterial thrombosis. Involvement of the airway in conflagrations carries special hazards like glottic edema and inhalation of irritant fumes. Nowadays, bacterial causes are dominant and these remain the main challenge. Bacterial infection and invasion of the burn are usually responsible for septicemia, bronchopneumonia, and pyelonephritis although other sources also contribute. Indirect manifestations of septicemia include paralytic ileus, acute gastric dilatation, toxic myocarditis, and some cases of renal failure. Therapeutic complications like agranulocytosis, thrombocytopenia, and colitis occur at times. High concentrations of oxygen given therapeutically can produce fatal aseptic hypoxic pneumonitis.
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PMID:A review of the complications of burns, their origin and importance for illness and death. 44 73

Doppler ultrasonography, a rapid, noninvasive and portable technique, has been available to clinicians for more than 10 years, but its accuracy in detecting deep vein thrombosis (DVT) has been questioned. A consistent and detailed method for testing venous circulation in the lower extremities is described. This method was used in a prospective study in which results of 50 phlebograms were compared with those of the Doppler test. A specificity of 92% and sensitivity of 100% were demonstrated, indicating that Doppler ultrasonography is a useful and accurate screening test for DVT.
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PMID:Doppler ultrasonography for detection of deep vein thrombosis in lower extremities. 45 21

The plasma concentrations of free fatty acids were estimated at intervals before, during and after total hip arthroplasty in seven patients. Each patient underwent examination for deep vein thrombosis with iodine-125 leg scanning, impedance plethysmography and contrast venography. Substantially higher concentrations of free fatty acids were found in the plasma of patients shown to have thrombosis than in those without thrombosis.
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PMID:Thrombosis and free fatty acids in patients subjected to total hip arthroplasty. 45 67

The prevalence of pelvic phleboliths was compared in 359 Melanasian patients and 169 white patients in Port Moresby, Papua New Guinea, and was found to be 12% and 51% respectively. The number and the size of phleboliths were also greater in white patients. These findings are similar to the data available from other parts of the world. The lower prevalence of pelvic phleboliths (and deep vein thrombosis) in Papua New Guineans may be related to their high fibre content diet, to their more active fibrinolytic system, or to both.
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PMID:Pelvic phleboliths: a study of 528 melanesian and white patients in papua new guinea. 46 23

Deep venous thrombosis is associated with increased heat emission from involved muscle groups and deviation of blood flow from the deep to the superficial venous system. Both of these features can be documented by thermography. An appreciation of the muscular and venous anatomy of the lower limb allows recognition of predictable thermographic images reflecting involvement of various muscle groups in the leg. It is expected that these anatomically based criteria will improve the diagnostic accuracy of thermography and offer a noninvasive, easily repeatable modality of examination for the diagnosis of deep venous thrombosis.
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PMID:Thermographic diagnosis of deep venous thrombosis: anatomically based diagnostic criteria. 46 87

In 173 legs with crural ulcers and postthrombotic syndrome proved by phlebography the frequency of involvement of the 4 levels of deep venous system was assessed. The results were compared with those obtained from a group of patients with acute or subacute deep vein thrombosis. The partly very distinct discrepancies may probably be explained by long lasting dynamics of the venous changes (spontaneous lysis, recurrent thrombosis). For the development of severe signs of venous insufficiency the involvement of the lower leg level may be the only cause in many instances.
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PMID:[The localization of postthrombotic changes in the different levels of the venous system of the leg (author's transl)]. 46 57

From 1973 to 1977 a total of 63 patients with thrombosis of the deep veins in leg and pelvis and in the V. cava inferior was treated by operative thrombectomy. Prior to the operation all patients were submitted to phlebography. The mean age of all was 52 years. One patient died from pulmonary embolism during thrombectomy, there was no further hospital mortality. Because of low mortality incidence and rarely postthrombotic complications we prefer the operative treatment of deep vein thrombosis. The preoperative cavography helps to avoid pulmonary embolism during thrombectomy.
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PMID:[Operative treatment of deep vein thrombosis (author's transl)]. 46 96

Four low-dose heparin regimens were compared with respect to the postoperative frequency of deep venous thrombosis (DVT) diagnosed with the 125I-fibrinogen method and other thrombosis variables as well as to peroperative and postoperative bleeding. The study comprised 204 patients undergoing gastrointestinal surgery who received 5,000 IU of either calcium heparin or sodium heparin (Vitrum AB) subcutaneously 2 hours before the operation and either every 8 or every 12th hours afterwards for 6--8 days. DVT was diagnosed in 17 and 16% of the patients who received calcium heparin every 8th or 12th hour respectively and in 11 and 10% respectively of those given sodium heparin every 8th or 12th hour. The differences in the incidence of DVT between the four groups were not statistically significant. An 8-hourly regimen was not accompanied by more bleeding incidents than a 12-hourly regimen. Sodium heparin was associated with a significantly increased number of patients who required blood transfusion and had more bruising at the injection site. It is concluded that the safest, most practical and still effective of the four investigated low-dose heparin regimens is calcium heparin 5,000 IU/ml administered 2 hours before the operation and every 12 hours afterwards for the first postoperative week.
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PMID:Optimal regimen of low-dose heparin prophylaxis in gastrointestinal surgery. 46 44


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