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Query: UMLS:C0149738 (neurological pain)
 30 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Painful neurological syndromes in cancer patients require comprehensive clinical assessment for their accurate diagnosis. Early diagnosis of the painful neurological syndromes in cancer patients allows the clinician to target his therapy toward preventing escalating pain, disability, and further neurological morbidity. Active rehabilitation is critically important in the management of these patients with neurological pain syndromes. Rehabilitation helps prevent further pain due to the development of secondary problems of immobility or disuse, helps the individual patient achieve his maximal level of functioning and helps each patient adapt to his/her neurological deficits.
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PMID:Neurologic pain syndromes in cancer patients. 2457 97

Pain is a common symptom in cancer patients. Thirty to fifty percent of patients will experience pain while undergoing cancer treatment, and 70 to 90% of patients with advanced disease report pain.1-7 In addition, greater than 50% of patients state their pain is incompletely controlled. In part, this is due to the difficulty physicians have in accurately assessing the patient's level of pain and response to treatment, as well as utilizing a treatment approach that is agreeable to the patient. It is common that patients underreport the severity of the pain that they are experiencing, as well as their inability to achieve pain control. There are many possible reasons for this, including their wish to appease the physician; the fear of confirming progression of their disease by admitting to having increased pain; and the concern of possible narcotic addiction. To address these problems, the World Health Organization, the American Pain Society, and the American Society of Clinical Oncology's Ad Hoc Committee on Cancer Pain have published guidelines for assessing and treating pain.8-10Pain is one of the most disabling conditions experienced by cancer patients.7,11-14 This disabling effect is exacerbated by the patient's fear of the loss of control of both the ability to regulate his/her pain and loss of control of his physical mobility due to the pain. Therefore, it affects the patient both physically and emotionally and further compromises the ability of the patient and family to deal with the disease.The perceived intensity of the pain as well as the level of disability experienced by the patient can be influenced by many variables such as family support and cultural background of the patient. These influences in the patient's life can magnify or diminish his/her perception of pain and disability. Therefore, in the same way that patients tolerate pain differently, the treatment approach must to some extent be appropriately individualized, periodically reviewed, and frequently altered to change with the needs of the patient. This is one reason why those involved with cancer rehabilitation use an individualized interdisciplinary approach to the patients' needs, including pain control. In addition to the traditional use of analgesics, chemotherapy, radiation therapy, surgery, and nerve blocks to palliate pain, cancer rehabilitation employs a wide range of other modalities, both physical and cognitive behavioral, in its treatment approach. Physical and occupational therapy utilize positioning, strengthening, transcutaneous electrical nerve stimulation (TENS), and other electrical stimulation modalities, orthotics, and other assistive devices to alleviate pain and maximize function. In addition, psychological support in its various forms, with both patient and family counseling, affords better handling of the disease. In some cases biofeedback and/or hypnosis can be utilized as an adjunct to pain control. Since the pathophysiology of cancer pain and its pharmacologic, surgical, and radiation treatments were dealt with in a previous issue, they will not be addressed further. This article will focus primarily on the more unique aspects of cancer rehabilitation, and the physical, nonpharmacologic, and behavioral approaches to pain management that practitioners commonly use in relation to neurological pain syndromes in cancer.
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PMID:Cancer rehabilitation approaches to neurologic pain syndromes in malignancy. 2457 42

Kidney cancer is the 9th most common cancer in men and the 14th most common in women worldwide. Renal cell carcinoma (RCC) constitutes 90% of all malignancies of the kidney. RCC, is known to be highly vascular and relatively radioresistant. Bone metastases are one of the most common metastatic sites and occur in around 30% of RCCs. They significantly impact the quality of life of patients causing pain and pathological fractures. Spinal metastases represent a particular case with regard to symptoms and treatment. Indeed, neurological pain is often added to the nociceptive pain caused by metastases. More importantly, neurological impairment can be seen, caused by spinal cord or nerve root compression (MSCC). Due to close contact with the spinal cord, the treatment of spinal bone metastases is challenging and requires a multidisciplinary approach. Specific treatment is currently focused on 4 main avenues which are surgery, radiotherapy, interventional radiology and systemic treatment. In June 2017 we carried out an extensive search on PubMed, Web of Science, and Cochrane Library to review the various treatment options and to establish a treatment strategy. This article presents the result of our critical review of the literature, given our expertise in the field.
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PMID:Treatment of spinal metastases in renal cell carcinoma: A critical review. 2965 Feb 72