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Query: UMLS:C0149521 (chronic pancreatitis)
 7,199 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The etiopathogeny and clinical aspects of chronic pancreatitis were studied in 80 patients. From the etiological point of view it was observed that 75 out of the 80 patients (93,75%) had had previous intense alcohol ingestion (mean 239.95 +/- 158.34 g of pure ethanol/day) during an average period of 12.5 years. A study of their diet showed that these patients ate significantly more protein than the controls (p less than 0.001). In 2 of the remaining 5 patients, the familiar form of the disease was characterized; in 1 there was a previous history of biliar disease and no etiological factor could be detected. The pathogenic implications of the excessive consumption of alochol associated with a high protein diet, as well as the main clinical characteristics presented by these patients are discussed.
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PMID:[Etiopathogenical and clinical aspects of chronic pancreatitis in San Pablo (Brazil): observations of 80 cases]. 9 57

Total duodenopancreatectomy was performed in a 36-year-old man because of global chronic pancreatitis. Islets cells were isolated by collagenase digestion from the resected pancreas and re-implanted into the liver via the portal vein. Until the sixth postoperative day the amount of insulin required fell from 54 IU initially to 10 IU per day. Serial insulin determination demonstrated secretion by the implanted cells.
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PMID:[Autotransplantion of Langerhans islets after total duodeno-pancreatectomy in a patient with chronic pancreatitis (author's transl)]. 10 66

A picture of acute abdomen developed in a 25-year-old patient with recurrent duodenal ulcers after subcutaneous injection of pentagastrin for a gastric secretion test. Laparotomy undertaken for suspected perforated ulcer revealed an acute hemorrhagic pancreatitis. Healing and freedom from complaint occurred rapidly with drug therapy. The following are to be considered as possible causes for pancreatitis after subcutaneous application of pentagastrin: exacerbation of the ulcer, an acute exacerbation of chronic pancreatitis, a direct effect of pentagastrin on the pancreas, increased pancreatic secretion due to the stimulation of gastric acid, reflux of duodenal contents or bile, arterial hypotension with local acidosis in the pancreas. Attention must always be paid to contra-indications of gastric juice analysis.
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PMID:[Acute pancreatitis following gastric secretion analysis by pentagastrin stimulation (author's transl)]. 10 81

False aneurysms of the pancreatic and peripancreatic arteries are a well recognized complication of chronic pancreatitis due to proteolytic enzymatic digestion of the arterial wall. These false aneurysms can be a source of life-threatening hemorrhage. Three cases are reported in which attempted embolizations of these bleeding aneurysms resulted in rupture into the gastrointestinal tract. Special precautions should be taken in such a procedure because of the inherent weakness of the aneurysmal wall.
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PMID:Aneurysm rupture secondary to transcatheter embolization. 10 84

Ultrasonic visualization of normal and pathological Wirsung's ducts has become quite common, especially with the newest gray scale units. Ductal images were studied in 17 cases of quiescent chronic pancreatitis. Duct dilatation could be identified in the majority
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PMID:Ultrasonic visualization of Wirsung's duct: dream or reality? 10 97

Four of 83 patients undergoing percutaneous transhepatic cholangiography were demonstrated to have hepatic abscesses communicating with the biliary tract. The abscesses resulted from obstruction of the common bile duct. The etiologies of the obstructions were chronic pancreatitis, recurrent cholangiocarcinoma. Radiographic demonstration of suppurative cholangitis is associated with a very poor prognosis.
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PMID:Diagnosis of pyogenic hepatic abscesses by percutaneous transhepatic cholangiography. 10 69

The infrequency of reports demonstrating dilatation of the pancreatic ducts in patients with chronic pancreatitis by CT, despite its frequent demonstration on endoscopic retrograde cholangiopancreatography (ERCP), prompted a review of 500 cases performed at the University of Miami School of Medicine/Jackson Memorial Hospital for suspected pancreatic disease. Pancreatic duct dilatation was demonstrated in 10 patients. An equal occurrence was documented in patients with chronic pancreatitis and with carcinoma. Therefore, the presence of dilated pancreatic duct only confirms the presence of pancreatic disease. No etiology should be favored by the isolated finding of a dilated duct on CT scanning.
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PMID:Significance of a dilated pancreatic duct on CT examination. 11 84

125 patients were subjected to computer tomography on account of suspected pancreatic disease. 48 patients were operated on--the computer tomography (CT) diagnosis was confirmed in 85.5% of the cases. Acute pancreatitis can be detected by CT if it is accompanied by an appropriate enlargement of the organ. Chronic pancreatitis can be recognized by deformations of the organ, calcifications or formation of pseudocysts. Pancreatic carcinoma is recognizable when it is larger than 3 cm accompanied by a change in the shape of the organ or if infiltration of neighboring structures has occurred. Computer tomography offers patients a safe, non-invasive method of performing follow-up examinations at short intervals.
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PMID:[Computer tomography on the pancreas. A diagnostic extension from the surgical aspect (author's transl)]. 11 64

Twenty three patients with acute pancreatitis were studied to assess the serum alpha 1-antitrypsin levels as well as the total trypsin-inhibitor capacity. These parameters were found to be normal or increased, which is not the case with patients with chronic pancreatitis. The value of protease-inhibitor treatment in acute pancreatitis is doubted.
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PMID:Alpha 1-antitrypsin and total trypsin-inhibitor capacity in acute pancreatitis. 11 90

Acid hydrolases (lysosomal enzymes) were analyzed and compared with trypsin in duodenal juice obtained after a test meal (Lundh test). The possible diagnostic role of acid hydrolases in pancreatic disease was investigated. In all patients with chronic pancreatitis normal values of acid hydrolases but subnormal trypsin activities were found. In pancreatic cancer normal values of acid hydrolases and normal trypsin values were seen in three patients with small tumors, whereas five patients with more advanced cancer of the pancreas had decreased trypsin activity and three of them high activities of acid hydrolases in duodenal juice. In five patients operated on with a gastroenteroanastomosis acid hydrolases were markedly increased. Five patients had no activity of acid hydrolases in the aspirate, probably reflecting technical failure with dislodgement of the catheter from the duodenum to the stomach. In conclusion the assay of acid hydrolases does not seem to increase the diagnostic value of the conventional Lundh test (trypsin).
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PMID:Intestinal lysosomal enzymes in the diagnosis of pancreatic disease. 11 5


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