Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149520 (acute cholecystitis)
 2,784 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To determine the feasibility of the use of Medicaid data to study drug-induced acute liver disease, we reviewed the medical records of 414 patients receiving Medicaid, age 20 or older, with an ICD-9-CM inpatient billing code consistent with acute hepatitis. Of the patients whose records were reviewed, 15.9% were alcoholics, 31.9% had acute hepatitis A or B, 13.5% were intravenous drug users, 8.2% had acute cholecystitis or choledocholithiasis, and 4.1% had received a blood transfusion within the previous 6 months. No diagnosis of liver disease was found in 10.6% of the patients, and 5.7% had chronic liver disease. Of the 169 patients with idiopathic acute liver disease identified, many had very mild liver disease and were hospitalized for reasons other than liver disease. We conclude that Medicaid billing data has high reliability and validity for the diagnosis of acute liver disease. However, primary medical records are essential for the study of drug-induced hepatitis, to be able to exclude other causes of liver disease, and to obtain information not included in the computer data.
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PMID:The feasibility of studying drug-induced acute hepatitis with use of Medicaid data. 150 56

Hospital admission rates for many gastrointestinal, hepatobiliary and pancreatic diseases were much higher in Aboriginals aged 15 to > 65 years than among the rest of the population of that age in Western Australia in 1989-91. Alcohol-related conditions were particularly prominent: the relative rate (RR) for alcoholic gastritis was > 30; for acute alcoholic hepatitis in young adults > 20; for alcoholic cirrhosis at 30-64 years the RR was about 4 to > 10; the RR for haematemesis and melaena was > 3; for acute pancreatitis at 30-64 years the RR ranged from about 3 to 20. Admissions for cholelithiasis in Aboriginal males were 1.5-2 times as frequent as in other males; for Aboriginal females the RR was > 2; acute cholecystitis was much commoner in Aboriginal patients from 30 to 64 years of age than in other patients of the same age. Illnesses coded as 'non-infectious enteritis and colitis' were the commonest diagnostic category in the International Classification of Diseases (ICD 9) classification of digestive system disorders among Aboriginal patients; admissions for these conditions occurred at double to more than seven times the rates that occurred in the same age groups in non-Aboriginal patients. Many of these illnesses were probably due to undetected gastrointestinal infections and parasitic infestations. This study shows that Aboriginal adults have disproportionately high rates of morbidity from many diseases of the digestive system. The findings have important implications for clinical services as well as for the development of preventive and promotional health strategies for Aboriginal people.
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PMID:Hospitalization of Aboriginal adults for digestive disorders in Western Australia, 1989-91. 754 9