Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149514 (bronchitis)
 6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Total hydroxyproline excretion in 24-hour urine was determined in 20 cases of systemic lupus erythematosus (SLE) before and during treatment. Additionally the excretion of hydroxyproline was determined in 14 patients receiving steroids for various other diseases (endocarditis, thrombocytopenia, acute leukemia, apofocal polyarthritis, ischialgia, spastic bronchitis, pleuritis and Dressler's post-infarction syndrome). The normal hydroxyproline value was established in 40 healthy persons. The normalization of pathologically increased hydroxyproline excretion in patients with SLE during treatment with prednisone in doses from 1.0 to 1.35 mg/kg/daily was associated with remission of clinical symptoms. Large doses of prednisone in pathological processes not primarily affecting connective tissue increased the 24-hour excretion of hydroxyproline and small doses of prednisone had no effect on hydroxyprolinuria.
Pol Med Sci Hist Bull
PMID:Effect of antiphlogistic steroids on urinary hydroxyproline excretion in systemic lupus erythematosus. 95 50

Concentration of alpha-fetoprotein (AFP) may be increased in some type of lung cancer. In the study concentration of AFP was evaluated in serum and broncho-alveolar lavage fluid (BALF) in patients with lung cancer. The values of concentration were compared with results obtained from patients with other diseases of the respiratory tract. Examinations were performed in 14 patients with lung cancer, 12 with sarcoidosis, 23 with chronic obstructive bronchitis and 16 with acute bronchitis. Liver pathology was excluded according to biochemical analytical tests. In all patients bronchofibroscopy was performed and BALF was obtained in routine way. Concentration of AFP in serum and BALF was determined by immuno-assay technique. In performed examinations non significant increase of AFP concentration was determined in serum and BALF of patients with lung cancer. However, obtained values were increased twice than in patients with acute bronchitis. Moreover, it was noticed that in patients with chronic obstructive bronchitis the AFP concentration was the highest, especially in the group treated by steroids. The study indicates that evaluation of AFP concentration is out of value in diagnosis and differentiation of lung cancer. It seems to be necessary to continue the examinations for explanation a role of steroids in inflammatory process and increase of AFP concentration.
Pneumonol Alergol Pol 1992
PMID:[Alpha fetoprotein levels in the serum and bronchoalveolar lavage fluid in patients with lung cancer and other diseases of the respiratory system]. 128 67

The session traced the course of health hazards in livestock confinement from anticipation of an emerging health hazard in 1974 to its full recognition as a significant health hazard in 1992. The session documented the major health hazards including hydrogen sulfide toxicity, bronchitis, non-allergic asthma, organic dust toxic syndrome, and mucus membrane irritation. In regard to exposures, bioaerosols seem to be the most significant hazard, with endotoxin evident as at least one of the major specific atiologic agents. Other agents were suspected, as newly recognized agents, specifically 1,3 beta-glucan. Previous epidemiological studies have revealed mild decrements in pulmonary function, however symptoms have always been excessively prevalent relative to controls. Recent results of a longitudinal observation showed a 12% drop out of workers with profound decrement in pulmonary function. In summary, the health hazard of livestock confinement workers is now well substantiated in North America and Europe and further work regarding prevention is highly indicated.
Pol J Occup Med Environ Health 1992
PMID:Lung dysfunction in animal confinement workers--chairman's report to the Scientific Committee of the Third International Symposium: issues in health, safety and agriculture, held in Saskatoon, Saskatchewan, Canada, May 10-15, 1992. 136 81

Cell morphology of BAL- fluid and index bronchitis (by Thompson) were evaluated in 52 patients with acute and chronic bronchitis. A significant increase of index bronchitis and percentage of neutrophils in BAL were observed in acute and chronic bronchitis. There was no correlation between index bronchitis and cell in BAL- fluid.
Pneumonol Alergol Pol 1992
PMID:[Cellular analysis of bronchoalveolar lavage fluid (BAL) in patients with acute and chronic bronchitis (preliminary study)]. 149 13

The lungs have an important role in the synthesis of angiotensin I converting enzyme (ACE). In BAL fluid and serum the ACE activity was determined in 18 patients with sarcoidosis (11 with high intensity and 7 with low intensity alveolitis), 14 patients with lung cancer and 16 with acute bronchitis. The activity of ACE was examined by a reagent set produced by Boehringer Mannheim Biochemica Test-Combination ACE cat. no. 789/011. The ACE activity in the high intensity alveolitis group of sarcoidosis patients was significantly increased in BAL fluid and serum in comparison to other observed patients. On the other hand, in patients with lung cancer the ACE activity was also increased in comparison to acute bronchitis and referred norms, especially in BAL fluid. This findings suggest a role of neoplastic process in ACE secretion in the airways. Very low correlation observed between ACE activity in serum and BAL fluid indicates a separate mechanism of secretion.
Pneumonol Alergol Pol 1991
PMID:[Activity of angiotensin I converting enzyme in serum and bronchoalveolar lavage fluid of patients with sarcoidosis and lung neoplasms]. 166 48

Ambroxol (Bronchopront-Mack) was administered to 73 patients with the bronchial asthma and spastic bronchitis with expectoration disorders. The drug was given in the dosage forms of slow release capsules, syrup, drops, intramuscular injections and inhalations for about 14 days. All patients have been carefully examined clinically, PEF has been measured, and sputum physico-chemical properties have been tested prior to and 10 days after treatment. Complete disappearance of cough, liquefaction of sputum and clearance of airways have been achieved in 47% of patients. A significant improvement has been noted in 38.4% of cases. The treatment failed in 2.7% of patients. Ambroxol has been well tolerated. No adverse effects on laboratory findings have been noted. Results suggest, that ambroxol is valuable drug in the combined treatment of patients with the bronchial asthma and spastic bronchitis.
Pol Tyg Lek
PMID:[Value of ambroxol in treatment of bronchial asthma and spastic bronchitis]. 166 82

In 10 patients of chronic bronchitis culture of mononuclear cells were performed. Supernatant was applied in inhalation. Bronchospasm was not observed in spastic bronchitis patients but it was present in asthmatic patients. In 50% of chronic bronchitis patients the inhalation test to histamine was positive.
Pneumonol Alergol Pol 1991
PMID:[Pulmonary ventilation after administration of lymphocytic supernatant to patients with chronic spastic bronchitis]. 172 11

Phadiatop test was performed in 174 children aged between 1 and 16 years (mean: 9 6/12 years) referred to the hospital because of the bronchial asthma, obstructive bronchitis and perennial or seasonal allergic rhinitis. Positive results were obtained in over 93% of children with atopic allergy. Comparing with PRIST, multiple allergen assay proved more sensitive (93.5%), specific (90%), and accurate (91.4%). The same data for PRIST were: 91.7%, 80.3%, 87.4%, respectively. False negative and false positive results were also less frequent than for PRIST. Therefore, Phadiatop, is considered an appropriate screening in vitro diagnostic test for inhalant allergy which should be performed at the beginning of respiratory tract diagnosis.
Pol Tyg Lek
PMID:[The value of Phadiatop screening tests for diagnosing allergic respiratory diseases in children]. 207 32

Cases of children with obstructive bronchitis are presented, which were referred due to a suspicion of bronchial asthma, cystic fibrosis, congenital errors of the large vessels, immunological disorders, and bronchial foreign bodies. The correct diagnosis of obstructive bronchitis led to resolving of symptoms in part of the children.
Pneumonol Pol
PMID:[Difficulties in diagnosing obstructive bronchitis]. 235 80

In order to study the familial occurrence of bronchial hypereactivity (BH) the parents of infants with BH were evaluated. 47 pairs of parents of infants aged 10-33 months were studied. All infants following spastic bronchitis developed BH. All parents had bronchial reactivity assessed. All answered a questionnaire from which the following data were retrieved: family history, personal history, environmental data and smoking habits. A similar analysis was carried out on a group of 19 pairs of parents forming a control group, derived randomly from hospital personnel. In parents of children with BH a higher incidence of BH was found in comparison with the control chi 2 = 11.52; p less than 0.01). In 14 subjects a positive familial history was found. This did not differ from the control. The smoking habit was seen more often in the study group that in the control (chi 2 = 9.82; p less than 0.01). These results allow us to state that familial factors play a role in bronchial hypereactivity in early infancy.
Pneumonol Pol
PMID:[Is bronchial hypersensitivity in early childhood genetically determined?]. 239 82


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