Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149514 (bronchitis)
 6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Medical examinations were performed of 138 pneumoconiosis (PC), 123 dust bronchitis (DB) cases and 28 pulmonary cases of non-occupational etiology. Fiber bronchoscopy with biopsy of bronchial mucosal tissue and, if necessary, transbronchial biopsy were performed in all the cases. Bronchial mucosa tattooing in persons exposed to different industrial aerosols did not depend on the forms of PC, DB and the diseases' stages. Nevertheless, it was established that, at more expressed stages of the disease and in case with complications (anthraco-tuberculosis), tattooing of the bronchial tree was more developed. In 92.3% cases, tattooing was formed in persons exposed to industrial aerosols containing more than 10% free silicon deoxide. On the tissue level, the morphologic substrate of the tattooing was lymphatic nodes obturating the coniophages and the coniotic infiltration of the bronchial mucosa connective tissue. Anthraco-tuberculosis induced specific inflammation contributed to the infiltration process due to the lymphodynamic disorders caused by lymphadenopathy.
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PMID:[Tattooing of the bronchial mucosa in patients with pneumoconiosis and dust bronchitis]. 191 5

The authors studied respiratory function in workers of wolfram-molybdenum mine where dust contains nearly 75% of silicon dioxide and considerable amounts of metals. The examinees were those with I stage silicosis and with silicosis complicated by chronic obstructive bronchitis. The respiratory disorders appeared most severe in association of the diseases.
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PMID:[Flow volume curve evaluation of respiratory function in wolfram-molybdenum miners]. 1141 20

Pneumonoultramicroscopicsilicovolcanoconiosis is fibrotic lung diseases of the pulmonary parenchyma following chronic inhalation of inorganic dusts containing crystalline silicon dioxide. The acute manifestations observed after heavy ashfalls include attacks of asthma and bronchitis, with an increased reporting of cough, breathlessness, chest tightness, and wheezing due to irritation of the lining of the airways. The chronic health condition of most concern is silicosis, a diffuse nodular fibrosis of the lungs, develops slowly, usually appearing 10 to 30 years after first exposure. A 35 years old male was admitted to Sardjito Hospital, Yogyakarta with complaints of progressive dyspnoea, right side chest pain since last 3 month and periodic episodes of dry cough. He had history of exposure to volcanic ash at the location around volcano eruption for about 10 month. Examination revealed hyperresonant note, diminished vesicular breath sounds in lower right side of the chest. The chest X-ray presence leads to bleb. Based on the clinical and radiological suspicion of pneumoconiosis the patient was submitted to computed tomography of the chest and revealed bilateral multiple bullae mainly at the right lung field. The biopsy specimen verified the diagnosis of anthrocosilicosis. There is no proven specific therapy for any form of silicosis. Symptomatic therapy should include treatment of airflow limitation with bronchodilators, aggressive management of respiratory tract infection with antibiotics, and use of supplemental oxygen (if indicated) to prevent complications of chronic hypoxemia.
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PMID:Traumatic Inhalation due to Merapi Volcanic Ash. 2658 90

(1) Background: Dermanyssus gallinae, a hematophagous ectoparasite, adversely affects the health status of laying hens, leading to reduced egg production and significant economic losses in commercial farms. The aim of this study was to determine the effect of D. gallinae on the development of post-vaccination immune responses in layer hens. (2) Methods: A total of 80 blood samples were collected at four time-points (B1-B4) from 10 Hy-Line Brown hens, randomly selected from a commercial layer farm. The flock was naturally infested with D. gallinae and treated twice with Biobeck PA 910 (AI silicon dioxide). The samples were collected before and after each treatment. The percentages of IgM+ B cells, CD3+/CD4+ T cells and CD3+/CD8a+ T cells were determined by flow cytometry; the titres of antibodies against avian encephalomyelitis, infectious bronchitis virus, Newcastle disease virus, Ornithobacterium rhinotracheale, reticuloendotheliosis virus and avian reovirus were determined by the immunoenzymatic method. (3) Results: The percentage of Th cells and post-vaccination anti-IBV and anti-NDV antibodies decreased significantly at the second infestation peak when the number of parasites was twice higher than at the first infestation peak. Non-significant negative correlations were found between the number of mites and the percentage of B cells (R = -0.845, p > 0.05) and between the number of mites and the percentage of Th cells (R = -0.522, p > 0.05), and a significant positive correlation was noted between the number of mites and the percentage of Tc cells (R = -0.982, p < 0.05). There were non-significant correlations between the number of mites and antibody titres. (4) Conclusion: The present findings suggested that D. gallinae might inhibit immune responses since the percentages of B cells and Th cells were negatively correlated with the number of mites. The percentage of Tc cells was positively correlated with the number of mites, which indicated that D. gallinae could stimulate cellular immune responses in infested laying hens. However, further research is needed to determine whether D. gallinae suppresses the production of vaccine-induced antibodies.
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PMID:Changes in the Percentages of B- and T-Lymphocytes and Antibody Titres in Laying Hens Infested with Dermanyssus gallinae-A Preliminary Study. 3251 4