Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0149514 (bronchitis)
 6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the period 1973-1982 241 children with nasal injuries were treated in ORL Clinics in Prague-Motol. The pathological septal findings were confirmed at the time by rhinoscopy in 98 cases (40%). In these cases, deviation, subluxation, or fracture were found 73 times, subperichondrial abscess 12 times, and hematoma 13 times. At the time of control examination 2-10 years after the injury, the unfavourable effects of the injury on the septum or the nasal passage were confirmed. Deviation of the septum was found in 55% of children; bad or insufficient rhinomanometric values in 62%. The septal deviation was associated with snoring in 52%, with colds in 56%, and in 37% with bronchitis and sinusitis. It was found necessary to carry out surgical correction of the nasal septum in several children of the 10-12 year age group; rhinotomy was not deemed necessary in any case.
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PMID:Late results of nasal septum injury in children. 409 52

Migraine is one of the common diseases, suffering 8.4 million patients in Japan. Recently conditions associated with chronic migraine were considered to be worse than episodic migraine in socio-economic status, health-related quality of life, and headache-related burden. Preventing the chronification, and improving treatment and management, the natural disease course could give us some clues. Several reports suggested that a population prevalence of chronic migraine is about 2% and approximately 2.5% of patients with episodic migraine develop new-onset chronic migraine each year. The risk factors for converting episodic to chronic migraine were demonstrated as follows: age, low education/socioeconomic status, head injury, attack frequency, obesity, medication overuse, stressful life events, caffeine overuse, snoring, other pain syndromes, allodynia, proinflammatory states, prothrombotic states, and specific genes. It was also focused in comobidity with chronic migraine, such as depression, anxiety, chronic pain, asthma, bronchitis, hypertension, and so on. The ratio converting in reverse was reported as a fourth in two years. We should recognize the burden of migraine patients, and improve patients' outcome under reducing risk factors and assessing the effect of treatment on headache progression.
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PMID:[Clinical course and natural history in migraine]. 2227 14