Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149514 (bronchitis)
6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One of the most important characteristics of asthma is its association with non specific bronchial hyperresponsiveness. This is diagnosed by histamine bronchial challenge tests. This latter is an easy procedure but requires a precise and standardized methodology. We have analysed, in a large group of bronchial challenge tests (n = 162) the clinical correlations with bronchial response to histamine. Our conclusions are in agreement with several recent literature, and may be summarised as follows: 1. more than 10% of patients, clinically considered as asthmatics do not show bronchial hyperresponsiveness and probably will not benefit from bronchodilators; 2. several aspecific respiratory symptoms (cough, chest tightness, blocked nose and sneezing, recurrent bronchitis, etc...) are frequently associated with bronchial hyperresponsiveness and should be considered as asthmatic manifestations. To conclude, we recommend to realise a histamine non specific challenge test in all cases of clinical suspicion of asthma (with normal lung function at basal state) and in all subjects presenting chest symptoms of uncertain etiology.
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PMID:[Screening in asthma]. 292 8

Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections in infants and children throughout the world. Respiratory syncytial virus infections in the elderly represent reinfections in the hosts who have had many prior episodes. Thus, RSV infections are usually not considered serious in adults, since reinfections are generally known to result in mild disease. Nevertheless, in adults, as in children, the infection has been reported to cause altered airway resistance and exacerbation of chronic obstructive lung disease. In people over 60 years of age, RSV usually causes mild nasal congestion, but can also result in fever, anorexia, pneumonia, bronchitis, and even death. Diagnosis of RSV infection in the elderly by the standard methods used in children is not as successful as in the latter group. This may be due to a combination of factors such as shorter shedding phase, lower viral titers, and dry mucosa. An alternative, rapid, and direct viral diagnostic method, the polymerase chain reaction, has recently been introduced in the diagnosis of RSV infections.
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PMID:Respiratory syncytial virus infection in the elderly. 907 95

Continuous positive airway pressure (CPAP) is a safe therapy for the management of obstructive sleep apnea (OSA). Complications such as sinus infection, bronchitis, ear pain, nasal congestion, and dryness of mucous membranes secondary to CPAP use have been reported. To follow, we describe a rare case of alternobaric vertigo secondary to CPAP therapy. To date, there has been only one reported case of hearing loss and vertigo during CPAP treatment with complete resolution of symptoms after cessation of PAP. However, re-challenging the patient with CPAP at gradual increments was never reported.
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PMID:Alternobaric vertigo in a patient on positive airway pressure therapy. 2434 Feb 99

Lippia microphylla Cham. (Verbenaceae) is an endemic underexploited Brazilian vegetal. This work reviewed the biological potentialities of Lippia microphylla, emphasizing the properties of essential oils (EOs) and analyzed scientific indicators about genus Lippia and L. microphylla. Databases from 1948 to the present were searched and a software (vantage point 7.1) associated with Derwent Innovation Index was used to identify the indicators of the genus Lippia, and biological activities and compounds in the L. macrophylla species. Ethnopharmacological records report use of L. microphylla leaves to treat gastrointestinal disorders, influenza, bronchitis, cough, nasal congestion, and sinusitis during vaporization, whose aromatic volatile oils are rich in monoterpenes, especially cineole, terpineol, and thymol. Other EOs have larvicidal activity on Aedes aegypti larvae, and antifungal, antibacterial and cytotoxic and antitumor action on human and murine cancer cells. Brazil is the country with more articles about Lippia species, but it deposited only 9 patents since 1993. Most of the publications about L. microphylla are concentrated in food and chemical sciences. This bioprospection helps to choice areas of interest for capital investment and to give support for Brazilian Institutions to establish cooperation and improve technological impact at the point of view of creation and innovation.
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PMID:Biomedical properties and potentiality of Lippia microphylla Cham. and its essential oils. 2640 17