Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149514 (bronchitis)
 6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In patients with chronic obstructive bronchitis, the rheological blood properties progressively deteriorate as the pulmonary insufficiency increases. These disorders are mainly caused by enhancement of red cell aggregation. The most remarkable disorders of the blood viscosity, e. g. the pathologically high viscosity syndrome, are recorded in patients with associated decompensated cor pulmonale and secondary erythrocytosis because of the hemoconcentration effect. Besides, the increase in the blood viscosity is dependent on the reduction in the propulsive capacity of the myocardium and acid-base unbalance. The role of the disorders of the blood viscosity in the pathogenesis of pulmonary hypertension is discussed.
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PMID:[Mechanisms of blood rheological disorders and their role in the progression of chronic obstructive bronchitis]. 400 59

Fluorometric analysis was carried out of the blood plasma content of free histamin (FH) and free serotonin (FS) in 27 patients with chronic non-obstructive bronchitis (ChNB), 52 patients with chronic obstructive bronchitis (ChOB) presenting with symptomatic erythrocytosis (SE) and in 29 normal subjects. Comparative analysis of the results obtained showed that in SE caused by ChOB the FH and FS content is significantly higher (p < 0.001) than in ChNB and in normal subjects. The FH content increases in SE with the augmentation in erythrocytosis. Positive dynamics was noted of FH and FS during the course of the disease treatment (p < 0.001).
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PMID:[Free histamine and free serotonin in the blood plasma in symptomatic respiratory erythrocytosis]. 783 11

Free histamine (FH) and free serotonin (FS) were studied fluorometrically in blood serum of 26 patients with genuine polycythemia (GP), 52 patients with chronic obstructive bronchitis (COB) associated with secondary erythrocytosis (SE) and 29 healthy subjects. On the grounds of the results of the study criteria of GP and COB-related SE were suggested. Diagnosis of GP can be considered valid if content of FH is no more than 3.1 times, FS content no less than 3 times and FH/FS ratio is no more than 2.65 times as much as normal. Levels of FH and FS and FH/FS ratio in SE related to COB are characterized by 4-fold and more, 2.9 and less and 4.64 and more increase respectively.
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PMID:[Biogenic amines in the differential diagnosis of erythrocytes]. 806 17