Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0149514 (bronchitis)
6,902 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

a survey of respiratory disease among male physicians of London, Ontario, resulted in a 96.3% response.The age-standardized rates of chronic bronchitis were not very different from others reported in the recent medical literature, taking into account smoking habits, but the overall prevalence of bronchial asthma was high (7.4%), with a low prevalence in the category "obstructive lung disease". The possibility of overlap or interchange in these diagnoses is raised, although the diagnosis of bronchial asthma in this particular group is believed to be well established in every case.A history of seasonal hay fever was given by 19.4%.One of 88 (1%) non-smokers had bronchitis, whereas six of them (7%) had asthma.Rhonchi heard in the chest, on a single examination, appeared to be most closely related to current smoking habits, ventilatory function tests and also to a clinical diagnosis of chronic bronchitis or obstructive lung disease, but not to bronchial asthma.
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PMID:The prevalence of chronic respiratory disease in the male physicians of London, Ontario. 541 24

The frequencies of several factors, including major physical disease, in employed and unemployed men enrolled in the British Regional Heart Study (BRHS) have been compared. The BRHS is a prospective study of cardiovascular disease in middle-aged men selected at random from general practices in twenty-four towns. The unemployed group was subdivided into those who said they were unemployed because of ill-health and those who regarded their unemployment as not due to illness. The ill unemployed reported a much higher rate of doctor-diagnosed illnesses than the not-ill unemployed or the employed. The frequencies of bronchitis, obstructive lung disease, and ischaemic heart disease were higher in the unemployed than the employed, with the highest rates in the ill unemployed. The frequency of hypertension was the same in employed and unemployed men. Cigarette smoking and heavy drinking were apparently more common among the unemployed, but after adjustment for social class and town of residence only smoking was slightly higher among the unemployed. Use of tranquillisers was three to four times more common in the ill unemployed than in the not-ill unemployed or the employed. In this study, the unemployed had far more chronic physical illnesses than the employed, whether or not the employed men regarded themselves as ill. Studies of the health consequences of unemployment must allow for the pre-existing state of health, and evidence on the state of health cannot rely solely on self-reporting of illness.
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PMID:Health of unemployed middle-aged men in Great Britain. 612 28

Since March 1981, 19 patients have undergone heart-lung transplantation for end-stage pulmonary vascular disease, with 14 long-term survivors. In five of the survivors, obstructive airway disease has developed with the superimposition of a progressive restrictive ventilatory defect in three of them. None of these five patients showed a tendency for spontaneous improvement of flow rates. Biopsy and postmortem material was available in four of the five patients and showed obliterative bronchiolitis (OB) in three. A fourth patient showed clinical and physiologic data consistent with obliterative bronchitis, but histologic material was not available. Obstructive lung disease without restrictive features developed in a fifth patient, but no histologic evidence of OB was found at transbronchial biopsy. In addition to OB, recurrent lung infections were found in all patients, significant pleural fibrosis in two patients, and bronchiectasis in one patient. Despite these long-term sequelae of human heart-lung transplantation, ten of the 14 surviving patients are leading relatively normal lives.
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PMID:Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. 643 51

Acute respiratory failure is a common life-threatening condition in old age. Structural alterations, progressive loss of lung functional reserves and weakening of pulmonary defense mechanisms are the main factors responsible. The aging lung itself contributes only little to the increased risk, but if combined with chronic lung disease, such as bronchitis, asthma, fibrosis, tuberculosis, pneumoconiosis, severe deterioration of lung function may occur. In many cases, respiratory failure results from an accumulation of the following factors: aging lung, chronic lung disease, cor pulmonale, acute complication. Today, chronic obstructive lung disease (COLD) is one of the most important conditions leading to ventilatory failure in the elderly. Carcinoma of the lung and other manifestations of malignant diseases may also be important. Treatment of the acute respiratory failure in the elderly must include three components: 1. treatment of the acute complication triggering the crisis, 2. treatment of the underlying chronic disease, 3. treatment of concomitant extrapulmonary diseases. After recovery, special attention must be directed towards preventing repeated respiratory failure.
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PMID:[Pneumologic emergency conditions in geriatrics. With special reference to risk factors]. 650 Apr 59

Most children with a cough have recurrent acute viral bronchitis or asthma. For both, the natural history is progressive improvement through childhood. An unrelenting cough with purulent sputum suggests suppurative lung disease and must not be dismissed lightly. In most cases the cause of cough can be determined by careful clinical history, physical examination and chest X-ray. Other laboratory investigations can be useful when underlying asthma is suspected.
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PMID:Children with cough. 673 39

Duration of smoking career, number of cigarettes smoked and smoke inhalation pattern seem to have a bearing on the occurrence of tobacco-related lung diseases. The authors therefore determined the smoking pattern and especially the time relation between drawing on a cigarette and inhalation in smokers with and without tobacco-related lung diseases. Based on clinical and radiological findings as well as pulmonary function tests, 91 smokers (without lung disease, with small airway disease, with simple chronic bronchitis, with obstructive bronchitis, with bronchitis and predominantly emphysema and with lung cancer) were examined. Smoking and breathing pattern were recorded using a smoke flow machine and a strain-gauge belt while smoking a cigarette. The blood level of COHb was determined before and after smoking. Of the smoking characteristics peak pressure, peak flow, time from drawing to inhalation and COHb difference varied significantly among the different groups. Drawing-to-inhalation time was lowest in smokers with chronic bronchitis and predominantly emphysema, which differed significantly from the other groups. This characteristic may be the consequence or the cause of emphysema. Regarding the latter, smokers with emphysema may perhaps lack the acute airway response to smoke inhalation and thus be able to inhale the cigarette smoke directly.
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PMID:[Does the manner of smoking affect chronic obstructive airway diseases and bronchial cancer?]. 682 40

After the May 18, 1980 volcanic eruption of Mount St. Helens, increases were observed in the number of patients who, because of asthma or bronchitis, sought medical care at emergency rooms of major hospitals in areas of ashfall. An interview study of 39 asthma and 44 bronchitis patients who became sick during the 4 wk following the eruption and who attended the emergency rooms of two major hospitals in Yakima, Washington, and of healthy matched controls indicated that a history of asthma, and possibly of bronchitis, were risk factors for contracting respiratory problems. The interview study also indicated that the main exacerbating factor was the elevated level of airborne total suspended particulates (in excess of 30,000 micrograms/m3) after the eruption. An interview study of 97 patients who had chronic lung disease and who lived in the same area as the above-mentioned patients, but who did not go to a hospital, showed that the ashfall exacerbated the condition in about one-third of these. Emergency planners and their geologist advisers should be aware that special preventive measures are justified for people with a history of asthma or chronic lung disease who live in communities at risk to volcanic ashfalls.
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PMID:Mount St. Helens eruptions: the acute respiratory effects of volcanic ash in a North American community. 687 Mar 51

Pathogen-free weaning rats of the LEW and F344 strains were caged together for two months to eliminate microbial and environmental differences, and then infected intranasally with 10-fold dilutions of viable Mycoplasma pulmonis. At necropsy 28 days post-inoculation, F344 rats had no gross lung lesions, even those given the maximum dose of 1.4 X 10(9) colony-forming units of M. pulmonis. LEW rats often had extensive gross lesions with a gross-pneumonia-dose50 of 1.1 X 10(7) colony-forming units/rat. Histological examination of the respiratory tract (nasal passages, larynges, tracheae, and lungs) and tympanic cavities showed both qualitative and quantitative differences in lesions between the two strains, particularly in the lungs. Hyperplasia of bronchus-associated lymphoid tissue occurred in both strains, but was more extensive in LEW rats. Atelectasis, alveolar consolidation (due primarily to mononuclear inflammatory cells), and suppurative bronchitis and bronchiolitis were seen only in LEW rats. Infiltrates of lymphoid cells into the lungs distal to bronchi and around blood vessels also were seen primarily in LEW rats. These differences between the two rat strains provide excellent model systems with which to dissect the role of cell responses in the pathogenesis of a naturally occurring chronic lung disease.
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PMID:Murine respiratory mycoplasmosis in LEW and F344 rats: strain differences in lesion severity. 697 66

Pulmonary mechanics, chest X-ray and the incidence of clinical lung disease were studied in 41 low birth weight infants treated with intermittent positive pressure ventilation (IPPV) in the neonatal period. Shortly after IPPV most patients, irrespective of X-ray findings, had signs of lung damage reflected in low dynamic compliance or high pulmonary resistance. Both parameters, however, had a strong tendency towards normalization during the first year of life. Overdistention on chest X-ray was common at 6--12 months of age. Pneumonia and bronchitis were common during the first two years of life but subsided later on. Development of BPD or later respiratory disease were not correlated to treatment with high inspired oxygen concentrations but commonest in patients with hyaline membrane disease. The combined findings of pulmonary mechanics and chest X-ray shortly after IPPV were correlated to later clinical lung disease.
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PMID:Pulmonary mechanics, chest X-ray and lung disease after mechanical ventilation in low birth weight infants. 701 Aug 95

Pulmonary blood volume (PBV) was measured by double injection (pulmonary artery trunk and wedged pulmonary artery) in 43 patients with chronic lung disease, at rest supine, with the legs raised, and during light exercise. At rest, PBV was reduced slightly in group 1 (eight with silicosis), but notably in groups 2 (16 bronchitis patients) and 3 (19 patients! with pulmonary vascular restriction). With the legs raised, PBV increased by 14 percent in group 1, 7 per cent in group 2, and 5 percent in group 3. From rest to exercise, the pressure increase was much greater in groups 2 and 3 than in group 1. The slope of the pressure-volume curve, delta V/delta P, was lower in groups 2 and 3, which could mean that lung vessel distensibility was reduced in these groups, or that, despite its low value, PBV was near its maximum capacity already at rest.
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PMID:Pulmonary blood volume in chronic lung disease: changes with legs raised and during exercise. 707 74


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