Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0086543 (cataract)
29,165 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1917
crystallin 714
lamp 408
Mol 300
aldose reductase 232
GSH 190
insulin 188
strabismus 186
She 176
collagen 175
ATPase 115
catalase 99
superoxide dismutase 99
calpain 92
aniridia 87
ATP 87
X-linked 86
glutathione peroxidase 86
vascular endothelial growth factor 81
ferritin 79
SRK 76
OCT 75
SDS 72
NMR 70
Pseudomonas 68
polypeptide 63
CAE 58
glutathione reductase 56
hole 54
albumin 53
MRI 52
lacrimal 51
vimentin 50
corneal dystrophy 50
hemoglobin 49
major intrinsic protein 49
connexin 48
alphaA-crystallin 47
hyaluronidase 47
endoplasmic reticulum 46
Cx46 46
fibronectin 42
tap 42
caspase-3 42
Aldose reductase 41
VEGF 40
HNE 39
cytokine 37
NADPH 35
reserved 34
alpha B-crystallin 33
smooth muscle actin 33
PAX6 31
LOCS 31
IL-6 30
heat shock protein 30
PCC 30
galactokinase 30
Bcl-2 29
membrane protein 29
sky 29
p53 29
serum albumin 28
HLA 28
UTR 27
MIP 27
CRYAA 27
transferrin 26
glucose-6-phosphate dehydrogenase 26
reductase 26
HSF4 25
SOD 25
Pol 25
ERG 24
proteasome 24
MYH9 23
SMA 23
asymmetrical 22
ASA 22
TGF-beta 22
more...
Disease
cataract 29165
glaucoma 2265
intraocular pressure 1220
blindness 1024
cornea 971
diabetes 938
retinal detachment 811
endophthalmitis 690
astigmatism 655
uveitis 653
myopia 616
IOL 536
aqueous humor 479
diabetic retinopathy 442
macular degeneration 419
cystoid macular edema 383
retinopathy 318
lens opacity 305
strabismus 302
cancer 288
keratitis 270
keratopathy 269
hypertension 255
amblyopia 238
corneal edema 234
macular edema 228
refractive error 219
eye disease 204
prolapse 199
conjunctiva 197
GSH 190
keratoconus 187
Anterior 181
tumor 167
neuropathy 155
sclera 150
anterior uveitis 139
Posterior 131
diabetic cataract 131
nystagmus 128
Alzheimer's disease 127
mental retardation 124
mental retardation 122
hyperopia 116
open angle glaucoma 114
retinitis pigmentosa 110
hyperglycemia 107
Age-related macular degeneration 102
melanoma 101
presbyopia 101
bilateral cataracts 98
ocular hypertension 96
proliferative diabetic retinopathy 96
diplopia 95
trachoma 93
iritis 91
renal disease 91
Posterior capsule opacification 91
conjunctivitis 89
DM1 88
depression 87
optic atrophy 86
osteoporosis 85
retinoblastoma 84
stroke 84
proliferative vitreoretinopathy 83
hypopyon 82
deafness 81
neovascular glaucoma 80
pulmonary tuberculosis 79
Best 77
akinesia 76
atherosclerosis 76
dysplasia 74
SDS 72
retinopathy of prematurity 71
iridocyclitis 71
arthritis 70
obesity 69
systemic disease 69
more...
Symptom
anesthesia 627
pain 332
weakness 129
dry eye 105
thinning 94
blurred vision 85
photophobia 71
discomfort 69
discomfort 67
hypotonia 56
diarrhea 54
seizures 52
ataxia 51
analgesia 40
headache 36
vomiting 34
erythema 30
collapse 27
cerebellar ataxia 25
aniseikonia 25
nausea 21
fatigue 20
ophthalmoplegia 20
eye pain 19
paresis 19
cough 15
hepatomegaly 15
polyuria 15
pallor 14
sleepiness 14
polydipsia 14
hepatosplenomegaly 13
Flare 12
angina 12
tremor 12
iridodonesis 12
metamorphopsia 11
spasticity 10
overweight 10
myalgia 10
hypertonia 9
respiratory distress 8
vertigo 8
agitation 7
splenomegaly 7
functional recovery 7
dyspnea 7
dystonia 7
dysarthria 7
dizziness 7
blepharospasm 6
numbness 6
anorexia 6
paresthesia 6
tinnitus 6
asthenia 6
ENT 6
Postoperative nausea and vomiting 5
tense 5
constipation 5
memory loss 5
Kayser-Fleischer ring 5
spasm 5
syncope 5
arthralgia 5
insomnia 5
Sedation 4
Macula 4
Floppy 4
abiotrophy 4
apathy 4
abdominal pain 4
starvation 4
muscle stiffness 4
joint stiffness 3
clubbing 3
polyopia 3
hyperoxia 3
back pain 3
carpopedal spasm 3
more...
Drug
ascorbate 139
vitamin E 99
lysine 79
balanced salt solution 75
Dermatol 55
Fluorescein 44
Fluorescein 44
Leaf 23
SF6 22
Monit 21
ROS 19
Sodium hyaluronate 19
Glutathione 19
DM1 18
Gel 18
Meditec 18
Galactose 18
FLP 18
Indomethacin 17
Diclofenac sodium 15
Vitamin E 14
Diphenhydramine 14
lactose 14
Voltaren 13
ADM 13
Timolol 12
Indocid 12
Hyaluronidase 12
Hyaluronidase 12
NADH 12
Dexon 11
Pilocarpine 10
Spectrum 10
caffeine 10
C3F8 10
Bendazac 10
Asn 9
Bevacizumab 9
Asthma 9
Xylocaine 9
Vicryl 9
Bromfenac 8
Albumin 7
Ketorolac 7
Dakar 7
Loteprednol etabonate 7
Azithromycin 7
Latanoprost 7
Ofloxacin 6
Xylocaine 6
Diamox 6
Xylocaine 6
Bupivacaine 6
Ocufen 6
ENT 6
Cardiovasc 6
Zmax 6
Diurnal 6
DEX 6
Dial 5
niacin 5
Ranibizumab 5
Mezlocillin 5
Ketorolac tromethamine 5
Timoptol 5
Nepafenac 5
PTH 5
CSF 5
Propofol 5
AMC 4
Clonidine 4
IL-2 4
Prednisolone 4
Ringer's solution 4
Nephron 4
IL-1ra 4
Indocyanine green 4
Cortisporin 4
Iopidine 3
TMS 3
more...
Enzyme
aldose reductase 236
superoxide dismutase 122
ATPase 118
catalase 110
glutathione peroxidase 93
focal adhesion kinase 87
glutathione reductase 53
hyaluronidase 48
ERK 47
hyaluronidase 47
mitogen-activated protein kinase 41
trypsin 34
caspase-3 34
glucose-6-phosphate dehydrogenase 32
galactokinase 31
luciferase 28
MIP 27
proteasome 26
peroxidase 25
protein kinase 24
sorbitol dehydrogenase 23
alcohol dehydrogenase 23
tissue plasminogen activator 22
carbonic anhydrase 21
lactate dehydrogenase 20
m-calpain 19
lysozyme 17
transglutaminase 16
chymotrypsin 14
ceruloplasmin 14
CYP27A1 13
glyceraldehyde-3-phosphate dehydrogenase 12
cytochrome oxidase 12
glyceraldehyde-3-phosphate dehydrogenase 11
alanine aminotransferase 11
hexokinase 11
reverse transcriptase 10
aldehyde reductase 10
caspase-9 10
glutathione S-transferase 10
protein kinase C 10
glyceraldehyde-3-phosphate dehydrogenase 9
creatine kinase 9
aspartate aminotransferase 9
uridyltransferase 9
xanthine oxidase 9
CPR 9
aldehyde reductase 9
aldehyde reductase 9
acid phosphatase 9
phosphoribulokinase 8
ACS 8
alkaline phosphatase 8
oxidosqualene cyclase 8
glyceraldehyde-3-phosphate dehydrogenase 7
tyrosinase 7
phosphofructokinase 7
plasmin 7
collagenase 7
glyceraldehyde-3-phosphate dehydrogenase 7
renin 7
calpain 3 6
aldehyde dehydrogenase 6
RNA polymerase 6
gamma-glutamyl transpeptidase 6
thrombin 6
malate dehydrogenase 5
DNA polymerase 5
calpain 10 5
complex I 5
mu-calpain 5
aldehyde dehydrogenase 5
NQO1 5
aldehyde dehydrogenase 5
lipase 5
glutathione synthetase 5
lactase 5
MsrA 5
CD10 5
indoleamine 2,3-dioxygenase 5
more...
Compound
Dec 1889
Clin 740
sodium 447
water 443
DNA 371
glucose 361
oxygen 342
calcium 309
galactose 245
GSH 201
GSH 201
Adrenal 142
His 137
iron 130
cysteine 125
phosphate 116
tryptophan 110
tryptophan 109
hydrogen 105
tryptophan 104
tryptophan 104
H2O2 100
lysine 89
ATP 87
arginine 85
SDS 79
urea 76
Retinal 74
acetate 72
potassium 71
tyrosine 66
zinc 63
iodine 62
salt 55
copper 54
sulfate 52
Pac 50
selenium 48
naphthalene 47
methionine 43
ASA 43
Asp 40
nitrogen 39
nitric oxide 38
NADPH 36
serine 35
NADPH 35
proline 33
STZ 32
creatinine 31
alanine 31
hyaluronic acid 31
Phe 28
aluminum 27
CO2 27
A 3 26
phosphorus 25
GSSG 25
Ascorbic acid 25
GAL 23
silicon 23
leucine 22
ethanol 22
glutamate 21
vitamin D 21
MTT 21
Dexamethasone 20
glutamine 20
Lutein 20
HEMA 20
Collagen 18
AMD 18
Galactose 18
PEG 18
Indomethacin 17
Gly 17
aldehyde 17
Vitamin E 17
TNF 17
HCl 16
more...