Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical and immunological studies in 170 patients with senile cataracts carried out before and during the first 7 days after cataract extraction with implantation of intraocular lenses helped define the risk factors for development of an early exudative reaction: patients' age under 60 years, clinical signs of secondary immune deficiency presenting as infection syndrome, increased levels of nonspecific immunity factors with deterioration of the phagocytic component, T-lymphopenia, CD4/CD8 imbalance, and increased levels of interleukin-1 beta and tumor necrosis factor in the serum and lacrimal fluid.
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PMID:[Clinical and immunological factors in predicting an early exudative reaction after extraction of senile cataracts with implantation of elastic IOL]. 1037 70

Results of crystallographic analysis of the lacrimal fluid in patients with glaucoma combined with cataract are analyzed. The characteristic features of lacrimal crystallograms of such patients consist in changed ratio of the crystallization zones with disappearance of the intermediate zone and appearance of stellate structures on crystallograms of patients with progressing cataracts. The method of lacrimal crystallography is suggested to be used in examinations of patients with glaucoma.
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PMID:[Crystallography of the lacrimal fluid as a method for predicting the risk of developing cataract in patients with primary glaucoma]. 1058 8

The degenerative processes of the lens, combined with the deficiency lacrimal secretion syndrome duct to the old age and high sensitivity, often need the use of drops containing potassium and iodum, drops Known as anticataractogen drugs. Independent of the patient psychological balance status the decrease of visual acuity caused by the decrease of visual acuity caused by the senile cataracts, could be late with a time factor of 1.8-2.5 studied on a selected group of patients. We can conclusion that some forms of senile cataracts are associated with the deficiency of lacrimal substances which are essential in the lens metabolism. With the progression of time there isn't important improvement neither in congenital cataract nor in the traumatic cataract which progresses fast to opacification caused by direct or indirect lesion of the lens. The patients presenting senile cataracts at incipient stage or advanced are good responsive at the anticataractogen drugs. For a therapeutic successful is important to begin the treatment as early is possible, and to do this with regularity.
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PMID:[The specialist contribution--cataract]. 1064 Nov 20

Analysis of the lacrimal fluid of normal subjects and patients after cataract extraction and with penetrating wounds of the eyeball showed fluctuations of the R protein concentration, which depended on the type of the injury and its complications. The authors propose using measurements of R protein in the lacrimal fluid as a prognostic criterion predicting the development of infectious complications in penetrating wounds of the eyeball.
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PMID:[Prediction of infectious complications of eye penetrating wounds by R protein concentration in lacrimal fluid]. 1066 84

Rubinstein-Taybi syndrome is a constellation of clinical findings characterized by mental and motor retardation, broad thumbs and broad first toes, typical facies. Ocular and adnexal abnormalities are quite common and include antimongoloid slant of the palpebral fissures, epicanthal folds, congenital obstruction of the lacrimal excretory system, ptosis, strabismus, congenital cataract and congenital glaucoma. The authors describe the case of a 1-year-old male with the Rubinstein-Taybi syndrome associated with unilateral congenital glaucoma. The case emphasizes the importance of detailed complete ocular examinations in patients with Rubinstein-Taybi syndrome, and also highlights the occurrence of ocular abnormalities rarely associated with this disease.
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PMID:[Goniodysgenesis associated with Rubinstein-Taybi syndrome]. 1093 97

The authors describe effective surgical rehabilitation of a female patient with corneal perforation and subsequent complicated cataract developing against the background of chronic deficiency of lacrimal production associated with Sjogren's syndrome which developed in the presence of rheumatoid arthritis. Treatment with artificial tears during complex pre- and postoperative therapy prevented serious complications and made unnecessary the preliminary interventions aimed at inhibition of lacrimal production. Long remission of the underlying disease and stability of visual functions during 2 years evidence the efficiency of rehabilitative measures.
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PMID:[Surgical rehabilitation of a patient with corneal perforation in keratoconjunctivitis sicca syndrome]. 1133 45

The incidence of ocular lesions in midfacial fractures ranges from 4 to 67%, depending on the criteria used in the previous examination. We report a retrospective study of 219 patients (233 fractures) who were admitted to our hospital between January 1990 and June 1994. The fractures are classified according to Henderson's classification (X-ray and Computed Tomography). We present the results of the ophthalmologic evaluation, after excluding palpebral lesions, and discuss the correlation with the etiology and the kind of fracture. The ocular lesions are divided into extraocular and intraocular ones. The extraocular lesions that we found are the following: damage to the lacrimal system, cranial nerve damage, displacement of the eye, corneal erosion and corneal foreign body and conjunctival lesions (subconjunctival hemorrhages, lacerations and chemosis). The intraocular lesions studied are divided into lesions of the anterior structures (hyphema, traumatic cataract, lens dislocation and hernia of the iris) and lesions of the posterior structures (vitreous and macular hemorrhage, eyeball perforation, optic nerve damage and Berlin's edema). Our conclusion is that comminuted fractures, fractures of the orbital rim only and those of the orbital floor are the most frequently associated with ocular damage, being mainly caused by automobile accidents and assaults.
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PMID:Ocular injuries in midfacial fractures. 1204 18

Total antioxidant activity of the lacrimal fluid (TAALF) was studied by luminol-dependent iron-induced chemiluminescence in an original model system on citrate phosphate buffer. Total antioxidant activity was estimated in percent of control (light sum of the model system fluorescence). The mean decrease of the light sum of the model system fluorescence in the presence of normal human lacrimal fluid supernatant was more than 50%, in glaucoma 67.2 +/- 4.43%, in cataract 58.5 +/- 2.61%, and in uveitis 76.9 +/- 1.13% of control. Traditional therapy of uveitis was associated with an increase of TAALF. Use of the proposed method for TAALF evaluation together with clinical data allows justified and individual antioxidant treatment of patients with ocular diseases and helps monitor the treatment efficiency. The study is noninvasive, cheap, and simple, which recommends evaluation of TAALF in clinical practice as a rapid test indicating the level of free radical oxidation in ocular tissues.
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PMID:[Total antioxidant activity of the lacrimal fluid]. 1208 1

Effects of low-intensive laser and alternating magnetic field on the course of the postoperative period were studied in patients with exudative reaction after extracapsular cataract extraction with implantation of intraocular lens (IOL). The results are analyzed for 148 eyes with early exudative reaction after IOL implantation (136 patients aged 42-75 years). The patients were observed for up to 6 months. The treatment efficiency was evaluated by the clinical picture of inflammatory reaction, visual acuity, and results of biochemical analysis of the lacrimal fluid (the ratio of lipid peroxidation products to antioxidants in cell membrane). The course of the postoperative period was more benign and recovery sooner in patients of the main group in comparison with the control.
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PMID:[Laser magnetotherapy after cataract extraction with implantation of intraocular lens]. 1222 69

We have examined 87 patients with chronic diffuse liver diseases with viral etiology and 20 healthy patients with ophthalmological, immunological and biochemical methods. It was established that liver pathology produced by hepatitis B virus give exchanges in the conjunctival and perilimbic circulation of the corneal sensitivity, retinal and optic nerve dysfunctions and also complicated cataract. Clinical symptoms in ophthalmopathology are amplify with the liver pathology progression and it is associated with the autoimmune reactions development, underlined by the antigens against eye tissues, and by the biochemical seric and local (lacrimal) parameters. The changes in eye structures were found at young and middle age patients, fact which indicate the social aspect of the problem and the necessity of their observation. In the vasoactive product "Cavinton" used in the complex treatment of the liver viral pathology it was established the possibility of pharmacologic correction of the pathologic changes in the ocular microcirculation and optic system.
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PMID:[Ocular manifestations of hepatitis B]. 1532 36


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