Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From 1981-1982, 750 clinical specimens from patients who developed postoperative infections were processed in the ocular microbiology laboratory. Bacterial cultures were positive in 71.0%, fungal in 1.3% and another 1.4% yielded both. The remaining 26.3% were sterile. Infections were due chiefly to Gram positive organisms (63.6%); only 6.4% were due to Gram negative bacteria while 0.9% were due to both. Staphylococcus aureus (52.0%) was the most common isolate, followed by S epidermidis (37.2%). Pseudomonas aeruginosa and Acinetobacter calcoaceticus were the next frequent pathogens. Aspergillus was the most common fungus among the fungal isolates. The highest number of infections followed cataract extraction and keratoplasty. A vast majority of postoperative infections seem to be occurring with hospital acquired strains. Cloxacillin seems to be the most effective remedy for treating staphylococcal infections and polymyxin B for infections due to Pseudomonas. Chloramphenicol appears to be as effective as gentamicin for treating all infections.
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PMID:Postoperative ocular infections: an analysis of laboratory data on 750 cases. 643 98