Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Polyglycolic acid sutures were used in 239 cases of intraocular surgery (164,6-0 size, 75, 7-0 size). Most of these (226) were cataract extractions. The results were excellent, with minimal complications. The 6-0 suture was somewhat stiff and associated with some tissue drag. The 7-0 size overcame these deficiencies and was considered the closest approach to date to the ideal absorbable suture. In addition, these appears to be an inhibition to bacterial penetration by PGA.
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PMID:Further use of polyglycolic acid (Dexon) sutures in cataract and other intraocular surgery. 111 10

6-0 Dexon (polyglycolic acid-PGA) suture was used in 30 eyes of 25 patients in surgical procedures which included cataract extraction, strabismus surgery, and ocular plastic surgery. The suture was found to hold the wound firmly, was not absorbed prematurely, was absorbed completely at a predicted time, was relatively easy to use although the knots were large, did not cause any infection or undue tissue reaction, and did not result in any wound dehiscence or vitreous loss.
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PMID:Evaluation of Dexon suture in ophthalmic surgery. 114 1

There is little published data on the incidence of eye disease in Asian patients with psoriasis. We determined the frequency of ocular complications in Singaporean Asian patients with chronic plaque psoriasis and related these to extent and severity of psoriasis, family history, treatment and presence of arthritis. A cross-sectional prevalence investigation was carried out in 100 patients who received a comprehensive eye examination. Psoriasis extent and severity was graded by the Lattice System Physician's Global Assessment (LS-PGA). Two patients (four eyes) had uveitis, one of whom had psoriatic arthritis (2% incidence). Presence or absence of uveitis correlated with mean LS-PGA scores. Sixty-three patients had cataract unrelated to previous steroid or phototherapy treatment; in younger (<50 years) patients they were commoner than in those with higher (>5) LS-PGA scores. Three eyes in two patients (2% prevalence) had glaucomatous optic neuropathy unrelated to previous treatment, and comparable with expected population frequency. These findings, although limited by lack of data from a comparable control population, suggest that eye complications are common in Asian patients with psoriasis and eye symptoms should be elicited during history taking. Besides signs and symptoms of eye disease, an LS-PGA score of more than 5 should prompt referral for ophthalmological examination.
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PMID:Psoriasis and the eye: prevalence of eye disease in Singaporean Asian patients with psoriasis. 1807 5

Elevated plasma Homocysteine level is an independent risk factor for age related (senile) cataract. Certain nutritional deficiencies, in particular Folate, Vitamin B(12), Vitamin B(6) relate inversely with Homocysteine level. This study was undertaken to evaluate the plasma level of Vitamin B(12), Folate, and Homocysteine of cataract patients and to study the interplay between them. Serum Homocysteine level is significantly increased in cataract patients when compared with control (p< 0.001). There was a significant decrease in the level of Folate as compared with control (p<0.001). There was a negative correlation between Homocysteine vs. Vitamin B(12) (p<0.01) and Folate (p<0.01) in the Cataract patients. Our findings suggest that increased plasma Homocysteine level is associated with decreased plasma levels of Folate and VitaminB(12) in Cataract patients, which might have a possible role in the root cause of cataract pathogenesis.
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PMID:Plasma Homocysteine, Folate and Vitamin B(12) levels in senile cataract. 2310 65