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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We have done two argon-laser iridotomies 24 and 72 hours before cataract surgery, to study ocular inflammation. We have taken aqueous samples to study IgA, IgG, C3 and AAT by laser immunonephelometry. All the proteins raised in the first 24 hours (P less than or equal to 0.01) except IgA in aqueous humor, taken with control levels, but only AAT (P less than or equal to 0.05), albumine at 72 hours (P less than or equal to 0.01) in aqueous humor. We tried to understand the observed gap by immunomodulation of released mediators.
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PMID:[Humoral immunity and the argon-laser]. 225 Sep 67

The aim of the study was to calculate the corneal endothelial permeability (Pac) before, one week, and one month after planned extracapsular cataract extraction and intraocular posterior chamber lens implantation in two groups with axial myopes (8 eyes) and normal eyes (6 eyes): in patients aged 60-75 years. Patients with minimal endothelial disorders have been found to have abnormal endothelial permeabilities. Each operated eye was submitted to fluorophotometry of the anterior segment with measurement of corneal endothelial permeability (Fluorotron Master, Coherent), the day before surgery, 1 week and 1 month afterwards. The measuring of cornea thickness measurement and endothelial cell counting was done by specular microscopy with pachymeter. Corneal permeability clearly increased 1 week after surgery in both groups; 1 months after surgery Pac was normalized in both groups, except for all pseudophakic myopic eyes (axial length: 25-27 mm) with longer surgical procedures (> 20 min), those associated with a greater increase in corneal endothelial permeability. No changes in corneal thickness and endothelial cell density were noted as a result of surgery. Myopic eye with longer surgical procedures was found as a risk factor for an increase in corneal endothelial permeability.
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PMID:[Fluorometric estimation of corneal endothelium functions in emmetropic and myopic eyes in pseudophakia]. 853 50

Accumulated evidence from experimental and epidemiological studies indicates that there is a low risk of degenerative diseases, cardiovascular disease, hypertension, cataract, stroke and, in particular, cancers in people with a high intake of fruit and vegetables. This protective effect is assumed to be associated mainly with the antioxidant activities of either individual or interacting bioactive components present in the fruits and vegetables, and with other biochemical and physical characteristics of the identified and unknown bioactive components. The implicated bioactive components present in citrus fruits include vitamin C, beta-carotene, flavonoids, limonoids, folic acid, and dietary fibre. A high intake of citrus fruits may reduce the risk of degenerative diseases.
Asia Pac J Clin Nutr 2002
PMID:Anticancer and health protective properties of citrus fruit components. 1189 Jun 43

Cataracts induced by atopic dermatitis rarely occur in adolescent and young adult patients suffering from this problem. Lenticular opacity is an important ocular complication in atopic dermatitis. Although the cause of atopic dermatitis and its ocular complications are unknown, cataracts have been observed to develop and progress during periods of exacerbation of the dermatitis. We report the case of a 16-year-old boy with atopic dermatitis who abruptly developed cataracts in both eyes while suffering from severe skin itching which began 2 months before the initial examination. His peroxidation test result was very high, and we postulate the retinal peroxidation might play a key role in cataractogenesis. Lens aspiration and intraocular artificial lens implantation were performed smoothly with restoration of visual acuity in both eyes.
Asian Pac J Allergy Immunol 2000 Mar
PMID:Atopic cataracts in a child with atopic dermatitis: a case report and review of the literature. 1254 60

The objective of this study is to evaluate the relationship between reproductive exposures and age-related cataract among women. This was a hospital based case-control study. The study population included female patients, aged 50 years and above who attended the Eye clinic at the University of Malaya Medical Centre. The outcome measurement was based on ophthalmologic examination by an ophthalmologist. The data on exposure was obtained from face to face interview using a structured questionnaire. In order to reduce the recall bias, patients' medical records were used to substantiate the exposure status. Multiple logistic regression was used to assess the association of age-related cataract with exogenous estrogen usage (HRT and OCP) and duration of menses. Important confounders such as age, history of diabetes, cigarette smoking and steroids usage were controlled for in the analysis. Females with 29 years or less of endogenous estrogen exposure of, have almost three times the risk of developing age related cataract (adjusted OR 3.42: 95% CI: 1.28, 9.16), similarly among those with exposure of 30-32 years (adjusted OR 3.64: 95% CI: 1.08, 12.26). Hormone Replacement Therapy used for more than three years was found to be a protective factor of age-related cataract. There is evidence that reproductive exposure may play a role in reducing the occurrence of age-related cataract among Malaysian women.
Asia Pac J Public Health 2007
PMID:Relationship between reproductive exposures and age-related cataract in women. 1805 May 60

The author examined 753 adults from 5 atolls that form a part of "Outer Islands" region of Republic of Marshall Islands (RMI), during his supervisory tour (July -Nov 2002); the visit aimed at providing primary health care services to the communities of outer islands region. Only the pterygia are highlighted in the following text. Each individual had a detailed interrogation followed by physical examination and glucometer assay of fasting blood. The dominant ocular pathologies included pterygia (14.5%), cataract (12%) and aphakia (1.5%). Of these 109 cases of clinically asymptomatic pterygia, 95 (92%) were bilateral; the disease prevailed more among women (62%). Interestingly, residents of these atolls (esp. women) attended to daily chores on grounds (adjoining their dwellings) covered with brightly shining coral stones. There was no causal association of diabetes mellitus (DM) pterygium when compared with non- diabetics. It is likely that the atoll residents were exposed not only to atmospheric ultra violet radiation (UVR), but also to ultra violet reflections from such bright coral stones beds accentuating the total effect comparable to the role of sandy beaches.
Pac Health Dialog 2005 Mar
PMID:Coral stone landscape and pterygia; is there an association? 1818 68

India has been recognized all over the world for spices and medicinal plants. Both exhibit a wide range of physiological and pharmacological properties. Current biomedical efforts are focused on their scientific merits, to provide science-based evidence for the traditional uses and to develop either functional foods or nutraceuticals. The Indian traditional medical systems use turmeric for wound healing, rheumatic disorders, gastrointestinal symptoms, deworming, rhinitis and as a cosmetic. Studies in India have explored its anti-inflammatory, cholekinetic and anti-oxidant potentials with the recent investigations focusing on its preventive effect on precarcinogenic, anti-inflammatory and anti atherosclerotic effects in biological systems both under in vitro and in vivo conditions in animals and humans. Both turmeric and curcumin were found to increase detoxifying enzymes, prevent DNA damage, improve DNA repair, decrease mutations and tumour formation and exhibit antioxidative potential in animals. Limited clinical studies suggest that turmeric can significantly impact excretion of mutagens in urine in smokers and regress precancerous palatal lesions. It reduces DNA adducts and micronuclei in oral epithelial cells. It prevents formation of nitroso compounds both in vivo and in vitro. It delays induced cataract in diabetes and reduces hyperlipidemia in obese rats. Recently several molecular targets have been identified for therapeutic / preventive effects of turmeric. Fenugreek seeds, a rich source of soluble fiber used in Indian cuisine reduces blood glucose and lipids and can be used as a food adjuvant in diabetes. Similarly garlic, onions, and ginger have been found to modulate favourably the process of carcinogenesis.
Asia Pac J Clin Nutr 2008
PMID:Traditional Indian spices and their health significance. 1829 52

The objective of this study was to establish the prevalence of cataract and measure vision related quality of life among elders in Sri Lanka. The 4-part study consisted of a survey to establish cataract prevalence, a case control study of risk factors, an assessment of the National Eye Institute Visual Functional Questionnaire (NEI-VFQ), and a comparison of quality of life among elders with and without cataract. Cataract prevalence was 56%. Significant risk factors were age, being female, occupational exposure, lower social class, presence of chronic illnesses, and smoking. The NEI-VFQ was validated for use in Sri Lanka and quality of life of elders with cataract was significantly lower on the NEI-VFQ and 2 other standard measures. The findings inform the development of public health strategies for treatment and prevention of cataract in Sri Lanka where the impact of cataract is increasingly being felt with rapid population aging and are applicable to other developing countries.
Asia Pac J Public Health 2009 Jul
PMID:Vision-related quality of life among elders with cataract in Sri Lanka: findings from a study in Gampaha District. 1944 77

Carotenoids, especially lutein and beta-carotene, offer benefits to human health in general and to eye health in particular. However, more data on the contribution of plant foods to carotenoid intake is of importance for developing strategies for promoting eye health in regions where cataract is highly prevalent such as in South India. The most frequently consumed 5 uncultivated and 5 commercially grown South Andhra Pradesh leafy vegetables were selected based on interviews with 100 local women. The lutein and beta-carotene contents of fresh and cooked samples were determined using reversed-phase high performance liquid chromatography. Lutein values ranged from 53 to 143 microg/g and 58 to 175 microg/g in fresh and cooked samples, respectively. beta-carotene contents were found to range from 45 to 119 microg/g in fresh samples and from 40 to 159 microg/g in cooked samples. No significant difference was observed between the carotenoid contents of wild and commercially grown species. According to their reported frequency of consumption, the 10 species considered in this study contribute 40% of the daily recommended intake of beta-carotene. This is the first report of lutein content in fresh samples of Celosia argentea L., Rumex vesicarius L., Digera muricata (L.) Mart., and Amaranthus cruentus L. as well as in cooked samples of all species included in this study.
Asia Pac J Clin Nutr 2010
PMID:Contribution of selected wild and cultivated leafy vegetables from South India to lutein and beta-carotene intake. 2080 87

Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.
Asia Pac Allergy 2011 Jul
PMID:Current status of atopic dermatitis in Japan. 2205 99


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