Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An analysis of 54 cases of ARD, and a PRD control group, revealed that retraction of the posterior vitreous hyaloid was more severe in the aphakic eyes. On the basis of retinal break morphology, the ARD cases could be divided into two groups: (1) detachments that had resulted from small tears situated along the posterior slope of a peripheral retinal traction ridge and (2) detachments that had resulted from breaks that resembled those encountered in the PRD group. The yearly incidence of retinal detachment, in the 38 and over age group, was calculated to be 12 times greater for an aphakic eye. That increase in risk was thought to be due to the changes in vitreous morphology which follow cataract extraction.
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PMID:Aphakic retinal detachment. 115 62

From a total of 95 children treated on a long-term basis with corticosteroids as part of a chronic dialyzation programme on account of asthma, juvenile chronic arthritis and leukaemia in 23 (24%) posterior subcapsular cataract (PSC) was diagnosed. The authors consider as the risk factor the amount of corticosteroids in relation to body weight rather than the absolute dose. The danger of PSC develops after one year's administration of 0.3 mg/kg/day Prednisone or its equivalent. This fact is documented by two case-histories indicating the chronology of development of PSC in two-year-old patients, from clear lenses to the most severe affection in the group. The absolute amount of Prednisone was 5-10 mg, i. e. 0.5 mg/kg/day. In one of the two patients the cataract of one eye had to be operated. The patients should have dispensary examinations after one year and subsequently after six-month intervals in case of continuing corticosteroid treatment. An interesting finding was the observation of the incipient stage of PSC--a double dissociation in the area of the posterior "Y" seam.
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PMID:[Steroid cataracts in children]. 152 16