Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In our 114 patients with vitreous loss during a cataract operation there were 21 cases (18.4%) which resulted in severe after-effects leading to the conclusion that vitreous loss during a cataract operation provokes a more frequent development of postoperative complications. Therefore a careful surgical procedure with exact repositioning of the vitreous-free anterior chamber, as well as regular and careful follow-up examinations are required. At our hospital we regularly carry our a three-mirror-contact lens examination after four weeks to enable us to perform a preventive treatment of the retina if necessary. In the event of incarceration of the vitreous with traction, a vitrectomy must be considered. As far as initial maculopathies are concerned we observed in a few cases a positive effect that parabulbar cortisone prevented further development of the disease. Finally, we would recommend regular IOP controls in order to recognize secondary glaucoma at an early stage.
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PMID:Complications in aphakic eyes after vitreous loss. 729 41

281 eyes out of 330 were followed during 3 to 5 1/2 years after trabeculectomy. 32 eyes were drop-outs due to death and 17 eyes due to inability to participate in the examination program. The mean age at time of surgery was 66 years. A mean pre-operative IOP of 31 mmHg dropped to a mean post-operative level of 18 mmHg. In 57% a single trabeculectomy was considered enough to control the glaucoma. Post-operative medical treatment was considered necessary in 35%. In 87% the pre-operative progress of the field defect was arrested. A reoperation was performed in 8%. The early complications were very few, but in 25% slowly developing cataract was observed. A cataract extraction was performed in 29 eyes post trabeculectomiam with a favourable visual outcome. This study confirms the opinion that trabeculectomy is an atraumatic and efficient surgical procedure and a necessary therapeutic measure when the tolerable combination of antiglaucoma drugs proves insufficient to control the glaucoma.
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PMID:330 trabeculectomies. A long time study (3-5 1/2 years). 733 81

In an observational study 19 eyes with cataract and coexisting primary open angle glaucoma were scheduled to undergo combined procedure with ECCE-IOL and trabeculectomy. The aim of the present study was to investigate the results and the efficacy of combined surgery, when we extended the indication for surgery. Thus the surgical decision making was not based solely upon IOP readings, but also involved social/psychological factors. Median decrease in IOP (IOPpost-IOPpre) was significant through a 12-month observation period, p < 0.001. The number of medications dropped from 1.74 to 0.21, p < 0.01. Complication rate during operation and in the postoperative follow-up period was low. We conclude that it seems justified to extend the indication for combined surgery in cataract patients with coexisting open angle glaucoma in case of uncontrolled IOP, poor compliance, inability of sufficient medical care, or unacceptable medication. We recommend careful monitoring of the early postoperative IOP, even if hypotensive agents are given prophylactically.
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PMID:Indications and efficacy of combined trabeculectomy and extracapsular cataract extraction with intraocular lens implantation in cataract patients with coexisting open angle glaucoma. 749 44

It is suspected that PE+PCL will often lower IOP. IOP was measured by Goldmann applanation tonometry in 50 consecutive patients (12 males and 38 females) who were unliterally pseudophacic (28 right and 22 left eyes n.s.). They had an intact posterior capsule and were not suffering from glaucoma. Mean age was 76 +/- 10 years. Time intervals since cataract surgery ranged from 2 to 68 months (mean 15 +/- 17 months). Seventy-four percent (99% confidence interval: 61% < P < 87%) of the patients showed lower IOP (less than 90% of reference value) in the pseudophacic eye. Median IOP in pseudophacic eye was 12 mmHg vs 14 mmHg in phacic control eyes (P < 0.01). These results are in accordance with the hypothesis that PE+PCL usually leads to a long-term reduction in IOP.
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PMID:[Lowering intraocular pressure by phacoemulsification and posterior chamber lens implantation]. 754 48

A new method of small incision cataract surgery is presented which allows sutureless wound closure with a fistulating aperature for regulating IOP. After in-the-bag pcIOL implantation, a triangular opening is made into the posterior scleral valve and combined with a peripheral iridectomy. Sufficient regularization of the IOP and good visual results could be observed in the majority of all 61 eyes operated on using this method.
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PMID:No-stitch combined glaucoma cataract-surgery. 783 88

We evaluated the prophylactic effect of 0.25% Clonidine HCl on the increase of intraocular pressure after Nd: YAG laser therapy. IOP of 150 eyes using Clonidine and 119 eyes without Clonidine were measured before and 0.5, 1, 2, 24 hours after Nd: YAG application. Various stages of angle-closure glaucoma and after cataract were both included in the treated and control groups and were compared respectively. Overall, the incidence of increase of IOP in the Clonidine-treated group was significantly less (9.3%) than the group without Clonidine (63.0%); the incidence of marked increase (> 1.06kPa) was also significantly less (2.0%) than those without Clonidine (18.5%). The peak value of IOP after laser therapy in the treated group did not exceed 3.06 kPa. Therefore, topical Clonidine is recommended as an effective and safe procedure to prevent the intraocular hypertension in Nd: YAG laser therapy.
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PMID:[Topical clonidine in prevention of intra-ocular hypertension after Nd: YAG laser therapy]. 784 98

Extracapsular cataract extraction with IOL implantation was performed in 32 consecutive cases of glaucomatous eyes which previously had undergone trabeculectomy (group A). The only complication seen during surgery was one tear in the posterior capsule. The mean IOP on postoperative day 1 was 17.7 +/- 7.9 mmHg. After extracapsular cataract extraction in 68 glaucomatous eyes with no previous surgery (group B) the corresponding mean IOP was 21.7 +/- 7.5 mmHg (p = 0.015). However, the mean preoperative IOP level was lower in group A (group A: 14.3 +/- 4.0 mmHg, group B: 17.1 +/- 4.3 mmHg), so the increase in IOP was not significantly different in the two groups. In group A, 15.6% of the eyes had an IOP elevation exceeding 24 mmHg, compared to 30.9% of the eyes in group B. Four months postoperatively, the IOP was significantly reduced in group B and unchanged in group A (compared to preoperatively). Seventy-two percent of the eyes in group A and 79% of the eyes in group B achieved a visual acuity of 5/10 or better, respectively.
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PMID:Extracapsular cataract extraction in eyes previously operated for glaucoma. 797 54

This retrospective study was conducted to evaluate the results of Combined Surgery of Cataract and Glaucoma (triple procedure). The procedure of combined surgery were trabeculectomy and extracapsular extraction (14 eyes) versus trabeculectomy and phacoemulsification (15 eyes). The follow-up of both groups was at least 9 months and up to 16 months (mean: 12 months). The mean decrease of IOP was 12.4 mmHg and 8.9 mm Hg in the first and second group respectively. Instillation of Beta-blockers twelve months after surgery were more frequent in the first group (64.3%) than in the second (26.7%). Finally, the IOP values one year after surgery were equivalent in both groups (less than 19 mmHg in 93% of cases). The mean features to emphasize the delay of recuperation of the best corrected visual acuity: one month for phacotrabeculectomy, and three months for extracapsular with trabeculectomy. The frequency of complications was low in both groups. We observed more hyphemas but less secondary cataracts in the phacotrabeculectomy group. Phacotrabeculectomy could become a reference procedure for combined glaucoma and cataract surgery.
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PMID:[Combined cataract-glaucoma operations. Extracapsular extraction and trabeculectomy versus phacoemulsification and trabeculectomy]. 798 53

Thirty-four eyes undergoing phacoemulsification and trabeculectomy (PHACO + TRAB) were followed prospectively for 1 year postoperatively. The results of surgery were compared with those, obtained retrospectively, of the previous 34 extracapsular cataract extractions with trabeculectomy (ECCE + TRAB) performed by the same surgical team. All eyes received posterior chamber intraocular lens implants. Preoperatively, the two groups did not differ significantly in terms of age, gender distribution, or degree and duration of glaucoma and cataract. Mean postoperative follow up for the ECCE+TRAB group was 13.6 months; for the PHACO + TRAB group, 12.6 months (P = .1). As compared with the ECCE + TRAB group, the PHACO + TRAB group had earlier visual rehabilitation, less postoperative astigmatism (P < .001), and improved long-term intraocular pressure control (P = .04). Early postoperative pressure spikes occurred in 32% of the ECCE + TRAB eyes and in 23.5% of the PHACO + TRAB eyes (P = .2). Other postoperative complications occurred more commonly in the ECCE + TRAB group: hyphema (P < .001), fibrinous iritis (P < .01), choroidal detachment (P < .05), and hypotony (P < .05). Posterior capsular opacification was significantly more common in the ECCE + TRAB group (P < .02). These major differences probably are attributable primarily to the small incision used in phacoemulsification, which is associated with sustained IOP control during the operation, a small stable wound with low postoperative astigmatism, and early stabilization of refraction.
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PMID:Combined cataract extraction and trabeculectomy: phacoemulsification compared with extracapsular technique. 811 95

Cataract progression after trabeculectomy was investigated in a study of 47 eyes with exfoliative glaucoma (ExG) and in 20 eyes with primary open-angle glaucoma (POAG). Cataract progression was assessed from the need for cataract extraction, deterioration of visual acuity by > or = 2 Snellen lines, myopic change in the refraction and increase in the lens opacity value, measured with a Lens Opacity Meter 701. Measurements were made 6 and 12 months after trabeculectomy and at the follow-up visit at 26 +/- 11 months. ExG, age, hypotony (IOP < or = 5 mm Hg) lasting > or = 5 days and early postoperative IOP rise > 30 mm Hg were observed to be risk factors for cataract progression. In pairwise analysis of 14 patients, in which the unoperated eye served as the control, a myopic change of refraction was the most frequent indicator for a change in the structures of anterior segment, possibly indicating cataract progression.
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PMID:Development of cataract after trabeculectomy. 815 52


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