Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0086543 (cataract)
 29,165 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In all, 55 eyes of 55 patients were examined prospectively in random order with the Humphrey field analyzer [central field 76 points, full threshold strategy, single-stimulus presentation, response-button control (HFA 1); central field 76 points, defect-depth strategy, response-button control (HFA 2)] and the Dicon TKS-4000 [central field 76 points, defect-depth strategy, multiple-stimulus presentation, response-button control (DIC 1); central field 76 points, defect-depth strategy, multiple-stimulus presentation, voice control (DIC 2)]. Some 26 patients (47%) had glaucomatous field defects, 7 patients (13%) had lesions of the visual pathway, 5 patients (9%) had normal fields. The other 17 patients (31%) had field defects due to vascular lesions of the retina or the optic nerve, retrobulbar neuritis, cataract, dysthyroid optic neuropathy, disorders of the macula, or human immunodeficiency virus (HIV) retinopathy. The mean testing time for the whole study population was 5.2 +/- 2.7 min for DIC 1. The difference from the mean testing time for HFA 2 (6.4 +/- 2.7 min) is statistically significant (p = 0.0013). DIC 2 reduces the mean testing time to 4.9 +/- 2.6 min. The difference from DIC 1 is not statistically significant (p = 0.8110). A multiple-stimulus presentation and voice control seem to be useful methods to reduce the testing time in automated perimetry without a loss of accuracy. Voice control, as used in the DICON TKS 4000, still has to be improved, however.
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PMID:Multiple-stimulus presentation and voice control in automated perimetry. 147 32

The purpose of the investigation is to study the impact of cataract and age-related macular degeneration (AMD) on the results of frequency-doubling technology (FDT) perimetry. Three groups of patients over 40 years of age took part in the clinical trial: 1) patients with cataract only; 2) those with cataract and glaucoma; 3) those with AMD. A control group comprised healthy individuals. Group 1 and 2 patients underwent phacoemulsification (PE) with intraocular lens implantation. Humphrey (HFA) static threshold testing (24-2) (HFA perimetry) and the authors' modified FDT perimetry were used before and 3 to 6 months after surgery. Group 3 patients also underwent microperimetry and optic coherence tomography. Cataract with visual acuity 8/ 20 or worse decreased very similar perception according to the results of FDT perimetry and HFA perimetry. FDT perimetry revealed more scotomas in patients with cataract concurrent with glaucoma. HFA II perimetry was more sensitive in detecting AMD. AMD and visual acuity of 4/20 or worse decreased contrast perception in some central squares of FDT perimetry.
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PMID:[Impact of cataract and age-related macular denegeration on the results of various perimetry techniques]. 2060 91